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Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 03/2018, Volume 26, Issue 5, pp. 1026 - 1034
The TGFβ-TGFβR signaling pathway has been reported to play a protective role in the later stages of tumorigenesis via increasing immunosuppressive Treg cells... 
ALK | TGFβ | TGF | TGF-beta | TGFBR | CHEMISTRY, MEDICINAL | SERIES | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMISTRY, ORGANIC | KINASE DOMAIN INHIBITORS | REFINEMENT | OPTIMIZATION | TGF beta | SELECTIVITY
Journal Article
Molecules, ISSN 1420-3049, 10/2018, Volume 23, Issue 11, p. 2824
As new drugs for the treatment of malignant tumors, transforming growth factor-beta receptor 1 (TGF beta R1) antagonists have attracted wide attention. Based... 
TGFβ | Discovery Studio | TGF-beta | TGFBR | Antagonists | Pharmacophore | antagonists | DOMAIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | INHIBITORS | pharmacophore | TGF beta | CHEMISTRY, MULTIDISCIPLINARY
Journal Article
Journal of the American College of Cardiology, ISSN 0735-1097, 2015, Volume 65, Issue 13, pp. 1324 - 1336
Journal Article
Journal Article
Cellular Physiology and Biochemistry, ISSN 1015-8987, 11/2018, Volume 50, Issue 5, pp. 1754 - 1763
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 03/2013, Volume 168, Issue 6, pp. 1341 - 1354
Background and Purpose Fibroblast-to-myofibroblast differentiation is associated with scarring, an important issue in corneal surgery. Moxifloxacin (MOX),... 
TGFBR | fibroblast‐to‐myofibroblast differentiation | SMA | MOX | HCFs | mad2 phosphorylation | filament formation | CATARACT-SURGERY PATIENTS | OPHTHALMIC SOLUTION | ACTIVATION | MITOMYCIN-C | fibroblast-to-myofibroblast differentiation | PENETRATION | Smad2 phosphorylation | PHOTOREFRACTIVE KERATECTOMY | TGFBR1 | TGFBR2 | GROWTH-FACTOR-BETA | IN-VITRO | TRANSFORMING GROWTH-FACTOR-BETA-1 | SMA filament formation | PHARMACOLOGY & PHARMACY | EXPRESSION | Fluoroquinolones | Epithelium, Corneal - cytology | Humans | Transforming Growth Factor beta1 - metabolism | Aza Compounds - pharmacology | Endothelium, Corneal - pathology | Epithelium, Corneal - pathology | Smad2 Protein - antagonists & inhibitors | Quinolines - pharmacology | Topoisomerase Inhibitors - pharmacology | Osmolar Concentration | Protein Processing, Post-Translational - drug effects | Actin Cytoskeleton - drug effects | Cell Transdifferentiation - drug effects | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Epithelium, Corneal - drug effects | Phosphorylation - drug effects | Fibrosis - prevention & control | Wound Healing - drug effects | Protein-Serine-Threonine Kinases - metabolism | Smad7 Protein - metabolism | Recombinant Proteins - metabolism | Myofibroblasts - pathology | Endothelium, Corneal - cytology | Cells, Cultured | Smad2 Protein - metabolism | Transforming Growth Factor beta1 - genetics | Endothelium, Corneal - drug effects | Myofibroblasts - drug effects | Transforming Growth Factor beta1 - secretion | Myofibroblasts - cytology | Receptors, Transforming Growth Factor beta - antagonists & inhibitors | Receptors, Transforming Growth Factor beta - metabolism | Anti-Bacterial Agents - pharmacology | Smad7 Protein - biosynthesis | Eye | Collagen | Surgery | Bone morphogenetic proteins | Moxifloxacin | Transforming growth factors | Muscle proteins | Health aspects | Medical research | Beta | Research Papers | α-SMA filament formation
Journal Article
Journal Article
Cellular Signalling, ISSN 0898-6568, 12/2018, Volume 52, pp. 112 - 120
Journal Article
Journal Article
by You, W and Liu, Z and Zhao, J and Zheng, MN and Zheng, SY and Liu, X and Zhang, HT
JOURNAL OF THORACIC ONCOLOGY, ISSN 1556-0864, 07/2007, Volume 2, Issue 7, pp. 657 - 659
Introduction: TGFBRI *6A, a functionally polymorphic allele in the transforming growth factor beta receptor 1 gene (TGFBRI), has been hypothesized to increase... 
lung cancer | ALLELE | TGFBR 16A | susceptibility gene | case-control | TGFBR1-ASTERISK-6A | ONCOLOGY | RESPIRATORY SYSTEM | SUSCEPTIBILITY | VARIANT
Journal Article
Platelets, ISSN 0953-7104, 9/2011, Volume 22, Issue 6, pp. 452 - 460
Journal Article
15.