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Immunity, ISSN 1074-7613, 08/2011, Volume 35, Issue 2, pp. 260 - 272
Skin-resident dendritic cells (DCs) are well positioned to encounter cutaneous pathogens and are required for the initiation of adaptive immune responses.... 
EPIDERMAL LANGERHANS CELLS | INFECTIONS | CANDIDA-ALBICANS | POSITIVE SELECTION | IMMUNE-RESPONSES | IN-VIVO | CONTACT HYPERSENSITIVITY | HOST-DEFENSE | SELF-ANTIGENS | IMMUNOLOGY | TH17 CELLS | T-Lymphocyte Subsets - immunology | Skin - microbiology | Mannose-Binding Lectins - biosynthesis | Dendritic Cells - immunology | Antigens, Bacterial - immunology | Dendritic Cells - pathology | Lectins, C-Type - biosynthesis | Adoptive Transfer | Candidiasis - microbiology | Th17 Cells - metabolism | Candidiasis - immunology | Candidiasis - pathology | Dendritic Cells - metabolism | Skin - pathology | Disease Models, Animal | Th17 Cells - pathology | Candida albicans - pathogenicity | Lymphocyte Activation | Mice, Inbred C57BL | Antigens, Surface - biosynthesis | Cells, Cultured | Repressor Proteins - genetics | Mice, Transgenic | Basic-Leucine Zipper Transcription Factors - genetics | Candida albicans - immunology | Receptors, Antigen, T-Cell, alpha-beta - genetics | Mice, Knockout | Animals | T-Lymphocyte Subsets - parasitology | T-Lymphocyte Subsets - metabolism | Dendritic Cells - microbiology | Th17 Cells - immunology | Cross-Priming | Mice | T-Lymphocyte Subsets - microbiology | Th17 Cells - microbiology | Antigens | Dendritic cells | T cells | Analysis | Flow cytometry | Skin | Infections | Rodents | Colleges & universities | Immune system | Candida albicans | Candidiasis | Dendritic Cells | Repressor Proteins | Life Sciences | Immunology | Receptors, Antigen, T-Cell, alpha-beta | T-Lymphocyte Subsets | Mannose-Binding Lectins | Lectins, C-Type | Antigens, Bacterial | Th17 Cells | Antigens, Surface | Basic-Leucine Zipper Transcription Factors
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 01/2013, Volume 123, Issue 1, pp. 247 - 260
Journal Article
Journal Article
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 03/2009, Volume 119, Issue 3, pp. 565 - 572
Th17 cells are involved in. the pathogenesis of many autoimmune diseases, but it is not clear whether they play a pathogenic role in type I diabetes. Here we... 
ENCEPHALOMYELITIS | MEDICINE, RESEARCH & EXPERIMENTAL | INTERFERON-GAMMA RECEPTOR | NOD MICE | TGF-BETA | NONOBESE DIABETIC MICE | IN-VIVO | DIFFERENTIATION | T-HELPER TYPE-1 | EXPRESSION | CUTTING EDGE | Gene Expression - drug effects | Xenopus Proteins - genetics | Pancreas - cytology | Interleukin-17 - immunology | Th17 Cells - transplantation | Adoptive Transfer | Interferon-gamma - metabolism | Th1 Cells - immunology | Th1 Cells - transplantation | Th1 Cells - metabolism | Th17 Cells - drug effects | Th17 Cells - metabolism | Gene Expression - immunology | Receptors, Interleukin-12 - genetics | Th17 Cells - cytology | Diabetes Mellitus, Type 1 - immunology | Interferon-gamma - genetics | Macrophages - immunology | Nuclear Receptor Subfamily 1, Group F, Member 3 - genetics | Interleukin-12 - pharmacology | Basic Helix-Loop-Helix Transcription Factors - genetics | Antibodies, Monoclonal - pharmacology | Mice, Inbred C57BL | Receptors, Aryl Hydrocarbon - genetics | Interleukin-17 - genetics | Up-Regulation - genetics | Lymph Nodes - immunology | Lymph Nodes - cytology | Mice, SCID | Pancreas - immunology | Receptors, Interleukin - genetics | T-Box Domain Proteins - genetics | Down-Regulation - genetics | Cell Differentiation - immunology | Interleukin-17 - metabolism | Macrophages - metabolism | Animals | Cell Differentiation - drug effects | Diabetes Mellitus, Type 1 - blood | Interferon-gamma - immunology | Th17 Cells - immunology | Macrophages - drug effects | Mice, Inbred NOD | Mice | Th1 Cells - cytology | Blood Glucose - metabolism | Causes of | Physiological aspects | Development and progression | Research | Diabetes | Autoimmune diseases | T cells
Journal Article
NATURE IMMUNOLOGY, ISSN 1529-2908, 06/2011, Volume 12, Issue 6, pp. 560 - U248
Although the role of the T(H)1 and T(H)17 subsets of helper T cells as disease mediators in autoimmune neuroinflammation remains a subject of some debate, none... 
ENCEPHALOMYELITIS | TGF-BETA | T(H)17 CELLS | COLONY-STIMULATING FACTOR | MULTIPLE-SCLEROSIS | DENDRITIC CELLS | IFN-GAMMA | FACTOR-DEFICIENT MICE | IN-VIVO | IMMUNOLOGY | TH17 CELLS | Peptide Fragments | Encephalomyelitis, Autoimmune, Experimental - metabolism | Granulocyte-Macrophage Colony-Stimulating Factor - metabolism | Interleukin-17 - immunology | Encephalomyelitis, Autoimmune, Experimental - immunology | Male | Th1 Cells - immunology | Th1 Cells - metabolism | Th17 Cells - drug effects | Flow Cytometry | Encephalomyelitis, Autoimmune, Experimental - chemically induced | Th17 Cells - metabolism | T-Lymphocytes, Helper-Inducer - immunology | Nuclear Receptor Subfamily 1, Group F, Member 3 - metabolism | Female | Interferon-gamma - genetics | Interleukins - pharmacology | Nuclear Receptor Subfamily 1, Group F, Member 3 - genetics | Interleukin-12 - pharmacology | Nuclear Receptor Subfamily 1, Group F, Member 3 - immunology | Th1 Cells - drug effects | T-Lymphocytes, Helper-Inducer - metabolism | Mice, Inbred C57BL | Cells, Cultured | Interleukin-17 - genetics | Myelin-Oligodendrocyte Glycoprotein | Mice, Transgenic | Glycoproteins | Mice, Inbred Strains | Granulocyte-Macrophage Colony-Stimulating Factor - genetics | Mice, Knockout | Animals | Granulocyte-Macrophage Colony-Stimulating Factor - immunology | Interleukin-23 - pharmacology | Interferon-gamma - immunology | Th17 Cells - immunology | Mice | Interferon-gamma - pharmacology
Journal Article
NATURE IMMUNOLOGY, ISSN 1529-2908, 06/2011, Volume 12, Issue 6, pp. 568 - U241
Interleukin 17 (IL-17)-producing helper T cells (T(H)17 cells) require exposure to IL-23 to become encephalitogenic, but the mechanism by which IL-23 promotes... 
EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | TGF-BETA | COLONY-STIMULATING FACTOR | ROR-GAMMA-T | INFLAMMATORY RESPONSES | HELPER-CELLS | REGULATORY T-CELLS | IMMUNOLOGY | IL-23 RECEPTOR | TH17 CELLS | CUTTING EDGE | Interleukin-1beta - pharmacology | Peptide Fragments | Encephalomyelitis, Autoimmune, Experimental - metabolism | Granulocyte-Macrophage Colony-Stimulating Factor - metabolism | Coculture Techniques | Encephalomyelitis, Autoimmune, Experimental - immunology | Th1 Cells - immunology | CD11c Antigen - immunology | CD11c Antigen - metabolism | CD4-Positive T-Lymphocytes - immunology | Th1 Cells - metabolism | Th17 Cells - drug effects | Flow Cytometry | Interleukin-23 - metabolism | Encephalomyelitis, Autoimmune, Experimental - chemically induced | Th17 Cells - metabolism | Nuclear Receptor Subfamily 1, Group F, Member 3 - metabolism | Antibodies - immunology | Female | Nuclear Receptor Subfamily 1, Group F, Member 3 - genetics | Nuclear Receptor Subfamily 1, Group F, Member 3 - immunology | Th1 Cells - drug effects | Mice, Inbred C57BL | CD4-Positive T-Lymphocytes - metabolism | Cells, Cultured | Myelin-Oligodendrocyte Glycoprotein | Mice, Transgenic | Glycoproteins | Interleukin-23 - immunology | Granulocyte-Macrophage Colony-Stimulating Factor - genetics | Interleukin-1 - pharmacology | Mice, Knockout | Antibodies - pharmacology | Transforming Growth Factor beta - pharmacology | Animals | Granulocyte-Macrophage Colony-Stimulating Factor - immunology | Interleukin-23 - pharmacology | Th17 Cells - immunology | Mice | CD4-Positive T-Lymphocytes - drug effects
Journal Article
Cancer Research, ISSN 0008-5472, 02/2011, Volume 71, Issue 4, pp. 1263 - 1271
The tumor microenvironment includes a complex network of immune T-cell subpopulations. In this study, we systematically analyzed the balance between cytotoxic... 
BREAST-CANCER | SURVIVAL | LUNG-CANCER | FOXP3 EXPRESSION | RECRUITMENT | ONCOLOGY | GASTRIC-CANCER | EOSINOPHILS | MACROPHAGES | CARCINOMA | LYMPHOCYTES | Th1 Cells - pathology | Th1 Cells - physiology | Prognosis | Th2 Cells - physiology | Tissue Array Analysis | Colorectal Neoplasms - genetics | Humans | Gene Expression Regulation, Neoplastic | Carcinoma - mortality | Gene Expression Profiling | Th2 Cells - immunology | Th1 Cells - immunology | Colorectal Neoplasms - diagnosis | Lymphocytes, Tumor-Infiltrating - physiology | T-Lymphocytes, Cytotoxic - pathology | Th1 Cells - metabolism | Th17 Cells - metabolism | Forkhead Transcription Factors - metabolism | Microarray Analysis | T-Lymphocytes, Helper-Inducer - immunology | Lymphocytes, Tumor-Infiltrating - metabolism | T-Lymphocytes, Helper-Inducer - pathology | Interleukin-4 - genetics | Th2 Cells - pathology | Th17 Cells - pathology | Colorectal Neoplasms - mortality | T-Lymphocytes, Cytotoxic - immunology | Th17 Cells - physiology | T-Lymphocytes, Helper-Inducer - metabolism | Carcinoma - immunology | Interleukin-4 - metabolism | Carcinoma - diagnosis | Forkhead Transcription Factors - genetics | Th2 Cells - metabolism | T-Lymphocytes, Cytotoxic - physiology | T-Lymphocytes, Helper-Inducer - physiology | Colorectal Neoplasms - immunology | Lymphocytes, Tumor-Infiltrating - pathology | T-Lymphocytes, Cytotoxic - metabolism | Survival Analysis | Th17 Cells - immunology | Carcinoma - genetics | Cohort Studies | Lymphocytes, Tumor-Infiltrating - immunology
Journal Article
Clinical & Experimental Immunology, ISSN 0009-9104, 08/2015, Volume 181, Issue 2, pp. 323 - 337
Summary Environmental factors, including microbes and diet, play a key role in initiating autoimmunity in genetically predisposed individuals. However, the... 
microbiota | segmented filamentous bacteria | systemic lupus erythematosus | immune modulation | autoimmunity | drinking water pH | Autoimmunity | Microbiota | Systemic lupus erythematosus | Drinking water pH | Segmented filamentous bacteria | Immune modulation | VITAMIN-D | CYTOKINES | INTERLEUKIN-9 | IMMUNOLOGY | ERYTHEMATOSUS | PATHOGENESIS | CELL SUBSETS | MURINE LUPUS | T-CELLS | TH17 CELLS | Plasma Cells - microbiology | Antibodies, Antinuclear - biosynthesis | Cyanobacteria - classification | Male | Gastrointestinal Tract - pathology | Plasma Cells - pathology | Clostridium - classification | Lactobacillus - classification | Plasma Cells - drug effects | Gastrointestinal Tract - immunology | Th17 Cells - drug effects | Time Factors | Female | Bacteroides - classification | Clostridium - immunology | Cyanobacteria - immunology | Lupus Nephritis - diet therapy | Drinking Water - administration & dosage | Th17 Cells - pathology | Lupus Nephritis - pathology | Lactobacillus - immunology | Genetic Predisposition to Disease | Microbiota - immunology | Bacteroides - immunology | Gastrointestinal Tract - microbiology | Lupus Nephritis - immunology | Mice, Inbred NZB | Disease Progression | Lupus Nephritis - microbiology | Animals | RNA, Ribosomal, 16S - genetics | Th17 Cells - immunology | Mice | Cytokines - biosynthesis | Th17 Cells - microbiology | Crosses, Genetic | Hydrogen-Ion Concentration | Plasma Cells - immunology | Lupus | Multiple sclerosis | Autoantibodies | Microbiota (Symbiotic organisms) | RNA | Analysis | Bacteria | Translational
Journal Article
Journal of Immunology, ISSN 0022-1767, 09/2011, Volume 187, Issue 5, pp. 2386 - 2393
Journal Article
Journal Article