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Biochemical Journal, ISSN 0264-6021, 10/2006, Volume 399, Issue 2, pp. 241 - 247
Group A streptococcus (Streptococcus pyogenes) is the causative agent of severe invasive infections such as necrotizing fasciitis (the so-called 'flesh eating... 
Mammalian glycoproteins | 1,2-dideoxy-2′-methyl-α-D-glucopyranoso-[2,1-d]- Δ | β-N-acetylglucosaminidase (GlcNAcase) | thiazoline (NAG-thiazoline) | MECHANISM | GLUCOSAMINIDASE | 1,2-dideoxy-2 '-methyl-alpha-D-glucopyranoso-[2,1-d]-Delta 2 '-thiazoline (NAG-thiazoline) | Spy1600 | BIOCHEMISTRY & MOLECULAR BIOLOGY | IDENTIFICATION | O-glycoprotein 2-acetamido-2-deoxy-beta-D-glucopyranosidase (O-GIcNAcase) | substrate-assisted catalysis | beta-N-acetylglucosaminidase (GlcNAcase) | SUBSTRATE | PURIFICATION | O-GLCNACASE | CLOSTRIDIUM-PERFRINGENS | mammalian glycoproteins | RESIDUES | BINDING | O-glycoprotein 2-acetamido-2-deoxy-beta-D-glucopyranoside (O-GlcNAc) | PARTICIPATION | Thiazoles - metabolism | Hyaluronoglucosaminidase - metabolism | Histone Acetyltransferases - chemistry | Escherichia coli | Humans | beta-N-Acetylhexosaminidases | Cercopithecus aethiops | Molecular Sequence Data | Multienzyme Complexes - metabolism | Substrate Specificity | Structure-Activity Relationship | Hymecromone - metabolism | Acetylglucosamine - metabolism | Hymecromone - analogs & derivatives | Acetylglucosaminidase - metabolism | Histone Acetyltransferases - metabolism | Acetylglucosamine - analogs & derivatives | Nuclear Magnetic Resonance, Biomolecular | Hymecromone - chemistry | Catalysis | Amino Acid Sequence | Acetylglucosamine - chemistry | Multienzyme Complexes - chemistry | Hydrolysis | Sequence Homology, Amino Acid | Animals | Acetylglucosaminidase - chemistry | Streptococcus pyogenes - enzymology | Thiazoles - chemistry | Kinetics | COS Cells | O-glycoprotein 2-acetamido-2-deoxy-β-D-glucopyranoside (O-GlcNAc) | ORF, open reading frame | GlcNAcase, β-N-acetylglucosaminidase | O-GlcNAc, O-glycoprotein 2-acetamido-2-deoxy-β-D-glucopyranoside | MU-GlcNAcF3, MU-2-deoxy-2-trifluoroacetamido-β-D-glucopyranoside | MU-GlcNAc, Mu-2-acetamido-2-deoxy-β-D-glucopyranoside | MU, 4-methylumbelliferyl | NAG-thiazoline, 1,2-dideoxy-2′-methyl-α-D-glucopyranoso-[2,1-d]-Δ2′-thiazoline | O-GlcNAcase, O-glycoprotein 2-acetamido-2-deoxy-β-D-glucopyranosidase | GlcNAc, N-acetylglucosamine (2-acetamido-2-deoxy-D-glucopyranose) | 1,2-dideoxy-2′-methyl-α-D-glucopyranoso-[2,1-d]-Δ2′-thiazoline (NAG-thiazoline) | O-glycoprotein 2-acetamido-2-deoxy-β-D-glucopyranosidase (O-GlcNAcase) | Spyl600 | MGEA5, meningioma expressed antigen 5 | MU-GlcNAcF1, MU-2-deoxy-2-fluoroacetamido-β-D-glucopyranoside | MU-GlcNAcF2, MU-2-deoxy-2-difluoroacetamido-β-D-glucopyranoside
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 10/2018, Volume 140, Issue 39, pp. 12574 - 12579
Native chemical ligation (NCL) is a simple, widely used, and powerful synthetic tool to ligate N-terminal cysteine residues and C-terminal α-thioesters via a... 
ISCHEMIA-REPERFUSION INJURY | THIAZOLINE | HYDROGEN-SULFIDE RELEASE | IN-VITRO | MECHANISM | KINETICS | BIOLOGY | CHEMISTRY | O-ARYL THIONOBENZOATES | CHEMISTRY, MULTIDISCIPLINARY | INSIGHTS
Journal Article
Canadian Journal of Chemistry, ISSN 0008-4042, 2018, Volume 96, Issue 2, pp. 248 - 254
Journal Article
Current Organic Synthesis, ISSN 1570-1794, 10/2015, Volume 12, Issue 1, pp. 20 - 60
Journal Article
Synlett, ISSN 0936-5214, 07/2016, Volume 27, Issue 12, pp. 1883 - 1887
Abstract A simple and versatile microwave-assisted protocol for the synthesis of 2-aminothiazoles has been developed. The domino reaction of propargylamines... 
letter | 2-aminothiazole | isothiocyanate | propargylamine | microwave chemistry | imidazol-thione | thiazoline | CYCLIZATION REACTION | SERIES | CHEMISTRY, ORGANIC | INHIBITORS | DERIVATIVES | THIAZOLES
Journal Article
Chemical and Pharmaceutical Bulletin, ISSN 0009-2363, 2014, Volume 62, Issue 8, pp. 735 - 743
This paper describes the synthetic studies conducted on a marine natural product, cyclodepsipeptide apratoxin A. Total synthesis of the oxazoline analogue of... 
Journal Article
Synlett, ISSN 0936-5214, 12/2016, Volume 27, Issue 20, pp. 2831 - 2835
Abstract A one-pot, three-component reaction has been developed and successfully employed for the synthesis of biologically relevant, highly functionalized... 
letter | Asinger | multicomponent reactions | oxindole | Ugi-Joullié reaction | spiro compounds | thiazoline | ISATIN | PEPTIDOMIMETICS | FACILE SYNTHESIS | ANTICANCER AGENTS | CHEMISTRY, ORGANIC | INHIBITORS | Ugi-Joullie reaction
Journal Article
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, ISSN 0376-4699, 07/2013, Volume 52, Issue 7, pp. 942 - 948
Journal Article
Journal of Carbohydrate Chemistry, ISSN 0732-8303, 11/2017, Volume 36, Issue 8-9, pp. 336 - 346
Endo-β-N-acetylglucosaminidases are a class of endoglycosidases that deglycosylate N-glycans from glycoproteins. We describe here a facile synthesis of a... 
complex type N-glycan | antibody | enzyme inhibitor | endo-β-N-Acetylglucosaminidase | Oligosaccharide thiazoline | enzymatic deglycosylation | Enzyme inhibitor | Complex type N-glycan | Antibody | Enzymatic deglycosylation
Journal Article
Journal of Enzyme Inhibition and Medicinal Chemistry, ISSN 1475-6366, 01/2018, Volume 33, Issue 1, pp. 445 - 452
GH20 human β-N-acetylhexosaminidases (hsHex) and GH84 human O-GlcNAcase (hOGA) are involved in numerous pathological processes and emerged as promising targets... 
O-GlcNAcase | inhibitors | naphthalimide derivatives | β-N-acetylhexosaminidase | Thioglycosides | CHEMISTRY, MEDICINAL | UNSYMMETRICAL DYADS | BIOCHEMISTRY & MOLECULAR BIOLOGY | GM2 GANGLIOSIDOSIS | NAG-THIAZOLINE | INSIGHT | D-GLUCOSAMINIDASE | beta-N-acetylhexosaminidase | ACETYL-D-HEXOSAMINIDASES | SELECTIVE INHIBITORS | DERIVATIVES | BINDING | Index Medicus
Journal Article
Advanced synthesis & catalysis, ISSN 1615-4150, 2018, Volume 360, Issue 4, pp. 779 - 783
A metal‐free oxidative difunctionalization of N‐allylamides and N‐allylthioamides has been developed. This system features the use of a hypervalent iodine... 
hypervalent iodine | oxazoline | thioamination | aminohydroxylation | metal-free | thiazoline | ELECTRON-RICH AMINES | ALLYL AMIDES | CHEMISTRY, ORGANIC | BOND FORMATION | CHIRAL NITRIDOMANGANESE COMPLEX | HETEROCYCLES | T-BUOI | N-ALKENYLAMIDES | DIAMINATION | OLEFINS | CHEMISTRY, APPLIED | CYCLIZATION | Olefins | Amines | Alkenes | Scaffolds | Benzene | Iodine
Journal Article
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