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Thrombosis and Haemostasis, ISSN 0340-6245, 02/2011, Volume 105, Issue 2, pp. 371 - 378
Journal Article
Clinical Pharmacokinetics, ISSN 0312-5963, 2008, Volume 47, Issue 1, pp. 47 - 59
Objectives: To investigate the pharmacokinetic and pharmacodynamic profile of dabigatran in healthy elderly subjects; to assess the intra- and interindividual... 
Dabigatran etexilate | Thrombin inhibitors | Elderly | Research and development | Pharmacotherapy | Internal Medicine | Medicine & Public Health | Pharmacology/Toxicology | Dabigatran etexilate, pharmacokinetics | Thrombin inhibitors, pharmacokinetics | REPLACEMENT | APTT | MANAGEMENT | THERAPY | VENOUS THROMBOEMBOLISM | TOTAL HIP | DISEASE | ETEXILATE | PHARMACOLOGY & PHARMACY | Anticoagulants - administration & dosage | Area Under Curve | Humans | Thrombin - antagonists & inhibitors | Pyridines - pharmacokinetics | Biological Availability | Male | Dabigatran | Flatulence - chemically induced | 2-Pyridinylmethylsulfinylbenzimidazoles - pharmacology | Diarrhea - chemically induced | Tandem Mass Spectrometry | Hematoma - chemically induced | Capsules | Benzimidazoles - administration & dosage | Aged, 80 and over | Chromatography, Liquid | Anti-Ulcer Agents - pharmacology | Female | Benzimidazoles - blood | Pyridines - administration & dosage | Administration, Oral | Benzimidazoles - pharmacokinetics | Anti-Ulcer Agents - administration & dosage | Anticoagulants - blood | Pyridines - blood | Blood Coagulation - drug effects | Partial Thromboplastin Time | Sex Factors | Aged | Anticoagulants - pharmacokinetics | Metabolic Clearance Rate - drug effects | 2-Pyridinylmethylsulfinylbenzimidazoles - administration & dosage | Index Medicus
Journal Article
Journal of Arthroplasty, The, ISSN 0883-5403, 2009, Volume 24, Issue 1, pp. 1 - 9
Journal Article
Journal of Thrombosis and Haemostasis, ISSN 1538-7933, 11/2011, Volume 9, Issue 11, pp. 2168 - 2175
Journal Article
Journal Article
Journal of thrombosis and haemostasis, ISSN 1538-7933, 2005, Volume 3, Issue 1, pp. 103 - 111
Background: Dabigatran etexilate is an oral direct thrombin inhibitor undergoing evaluation for the prevention of venous thromboembolism (VTE) following... 
direct thrombin inhibitor | total hip replacement | dabigatran etexilate | total knee replacement | deep vein thrombosis | venous thromboembolism | Deep vein thrombosis | Dabigatran etexilate | Total hip replacement | Total knee replacement | Venous thromboembolism | Direct thrombin inhibitor | XIMELAGATRAN | MELAGATRAN | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | LEG | Arthroplasty, Replacement, Knee - adverse effects | Pyridines - chemistry | Humans | Middle Aged | Thrombin - antagonists & inhibitors | Male | Dabigatran | Benzimidazoles - chemistry | Dose-Response Relationship, Drug | Thromboembolism - prevention & control | Aged, 80 and over | Adult | Female | Odds Ratio | Postoperative Complications | Double-Blind Method | Administration, Oral | Postoperative Period | Enoxaparin - pharmacology | Arthroplasty, Replacement, Hip - adverse effects | Regression Analysis | Anticoagulants - pharmacology | Benzimidazoles - pharmacology | Aged | Pyridines - pharmacology | Index Medicus | Anticoagulants/pharmacology | Benzimidazoles/chemistry/pharmacology | Thrombin/antagonists & inhibitors | Oral | Knee/adverse effects | 80 and over | Surgery | Thromboembolism/prevention & control | Drug | Administration | Pyridines/chemistry/pharmacology | Arthroplasty | Replacement | Enoxaparin/pharmacology | Kirurgi | Hip/adverse effects | Dose-Response Relationship
Journal Article
The Journal Of Clinical Pharmacology, ISSN 0091-2700, 05/2005, Volume 45, Issue 5, pp. 555 - 563
Dabigatran etexilate is an oral low-molecular-weight direct thrombin inhibitor. Following oral administration, dabigatran etexilate is rapidly converted to its... 
Dabigatran etexilate | Total hip replacement | Pharmacokinetics | Venous thromboembolism | Direct thrombin inhibitor | ENOXAPARIN | SURGERY | dabigatran etexilate | MANAGEMENT | total hip replacement | PREVENTION | DALTEPARIN | direct thrombin inhibitor | KNEE REPLACEMENT | venous thromboembolism | pharmacokinetics | DOUBLE-BLIND | PHARMACOLOGY & PHARMACY | II RANDOMIZED-TRIAL | Area Under Curve | Humans | Middle Aged | Thrombin - antagonists & inhibitors | Pyridines - pharmacokinetics | Male | Metabolic Clearance Rate | Dabigatran | Absorption | Drug Interactions | Aged, 80 and over | Adult | Female | Omeprazole - pharmacology | Sulfoxides - pharmacology | Proton Pump Inhibitors | Administration, Oral | Food-Drug Interactions | Benzimidazoles - pharmacokinetics | Arthroplasty, Replacement, Hip | Cross-Over Studies | 2-Pyridinylmethylsulfinylbenzimidazoles | Benzimidazoles - pharmacology | Aged | Omeprazole - analogs & derivatives | Prevention | Evaluation | Thrombophlebitis | Antithrombins | Research | Index Medicus | Thrombin/antagonists & inhibitors | Oral | 80 and over | Surgery | Benzimidazoles/pharmacokinetics/pharmacology | Administration | H(+)-K(+)-Exchanging ATPase/antagonists & inhibitors | Arthroplasty | Replacement | Pyridines/pharmacokinetics | Kirurgi | Hip | Sulfoxides/pharmacology | Omeprazole/analogs & derivatives/pharmacology
Journal Article
International Journal of Stroke, ISSN 1747-4930, 12/2015, Volume 10, Issue 8, pp. 1309 - 1312
Journal Article
Thrombosis and Haemostasis, ISSN 0340-6245, 06/2019, Volume 119, Issue 6, pp. 916 - 929
Abstract The direct thrombin inhibitor (DTI) dabigatran is a non-vitamin K antagonist oral anticoagulant for the prevention of stroke and systemic embolism in... 
Cellular Haemostasis and Platelets | GLYCOPROTEIN-IB-IX | ACTIVATION | GPIb | PROTEIN | RIVAROXABAN | aggregation | VON-WILLEBRAND-FACTOR | ADP | platelets | VONWILLEBRAND-FACTOR | von Willebrand factor | BINDING-SITE | PERIPHERAL VASCULAR DISEASE | GENERATION | ECHICETIN | HEMATOLOGY | direct thrombin inhibitors
Journal Article
Journal of Thrombosis and Haemostasis, ISSN 1538-7933, 09/2004, Volume 2, Issue 9, pp. 1573 - 1580
Background:  Dabigatran etexilate (BIBR 1048) is an oral direct thrombin inhibitor undergoing evaluation for the prevention of venous thromboembolism (VTE)... 
direct thrombin inhibitor | total hip replacement | dabigatran etexilate | deep vein thrombosis | Deep vein thrombosis | Dabigatran etexilate | Total hip replacement | Direct thrombin inhibitor | TRIALS | PROPHYLAXIS | KNEE REPLACEMENT | direct | MELAGATRAN | PERIPHERAL VASCULAR DISEASE | THROMBOEMBOLISM | thrombin inhibitor | HEMATOLOGY | Prodrugs - administration & dosage | Pyridines - administration & dosage | Administration, Oral | Humans | Middle Aged | Thrombin - antagonists & inhibitors | Benzimidazoles - pharmacokinetics | Pyridines - pharmacokinetics | Male | Dabigatran | Arthroplasty, Replacement, Hip - adverse effects | Dose-Response Relationship, Drug | Pyridines - adverse effects | Benzimidazoles - administration & dosage | Prodrugs - pharmacokinetics | Thromboembolism - prevention & control | Hemorrhage - etiology | Aged, 80 and over | Adult | Female | Venous Thrombosis - prevention & control | Aged | Safety | Benzimidazoles - adverse effects | Index Medicus | Drug | Hemorrhage/etiology | Administration | Prodrugs/administration & dosage/pharmacokinetics | Benzimidazoles/administration & dosage/adverse effects/pharmacokinetics | Thrombin/antagonists & inhibitors | Arthroplasty | Replacement | Oral | Pyridines/administration & dosage/adverse effects/pharmacokinetics | Kirurgi | 80 and over | Hip/adverse effects | Surgery | Thromboembolism/prevention & control | Dose-Response Relationship | Venous Thrombosis/prevention & control
Journal Article
American journal of physiology. Lung cellular and molecular physiology, ISSN 1040-0605, 2015, Volume 309, Issue 8, pp. L768 - L775
Journal Article
British Journal of Clinical Pharmacology, ISSN 0306-5251, 11/2006, Volume 62, Issue 5, pp. 527 - 537
Journal Article