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thrombin-induced increase (61) 61
animals (57) 57
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Circulation Research: Journal of the American Heart Association, ISSN 0009-7330, 07/2002, Volume 91, Issue 1, pp. 70 - 76
Journal Article
Blood, ISSN 0006-4971, 01/2012, Volume 119, Issue 1, pp. 308 - 319
Increased endothelial permeability contributes to the morbidity and mortality associated with chronic inflammatory diseases, including acute lung injury.... 
PULMONARY ENDOTHELIUM | BARRIER DYSFUNCTION | RHOA ACTIVATION | IN-VIVO | P190 RHOGAP | LUNG INJURY | HEMATOLOGY | THROMBIN-INDUCED INCREASE | NF-KAPPA-B | MICROVASCULAR PERMEABILITY | VASCULAR LEAKAGE | Endothelium, Vascular - cytology | Capillary Permeability - physiology | RNA, Small Interfering - genetics | Luciferases - metabolism | Humans | Capillary Permeability - drug effects | Endothelium, Vascular - drug effects | Hemostatics - pharmacology | Promoter Regions, Genetic - genetics | Histamine - metabolism | Pulmonary Artery - metabolism | Flow Cytometry | Thrombin - pharmacology | Chromatin Immunoprecipitation | Guanine Nucleotide Exchange Factors - metabolism | Electrophoretic Mobility Shift Assay | Real-Time Polymerase Chain Reaction | Repressor Proteins - metabolism | Guanine Nucleotide Exchange Factors - genetics | Signal Transduction | Mice, Inbred C57BL | RNA, Messenger - genetics | Cells, Cultured | Gene Expression Regulation | Microvessels - drug effects | Repressor Proteins - genetics | Pulmonary Artery - drug effects | Blotting, Western | Pulmonary Artery - cytology | Cyclic AMP Response Element-Binding Protein - genetics | Animals | Endothelium, Vascular - metabolism | Cyclic AMP Response Element-Binding Protein - antagonists & inhibitors | Cyclic AMP Response Element-Binding Protein - metabolism | Lipopolysaccharides - pharmacology | Mice | Vascular Biology
Journal Article
Journal Article
JOURNAL OF CELLULAR PHYSIOLOGY, ISSN 0021-9541, 02/1996, Volume 166, Issue 2, pp. 249 - 255
We studied the postulated involvement of the protein kinase C beta(1) (PKC beta(1)) isoform in the regulation of endothelial permeability using human dermal... 
TIGHT JUNCTIONS | CELLS | SMOOTH-MUSCLE | ACTIVATION | PHYSIOLOGY | DISRUPTION | PHOSPHORYLATION | ALBUMIN PERMEABILITY | VINCULIN | THROMBIN-INDUCED INCREASE | EXPRESSION | CELL BIOLOGY
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 04/2005, Volume 280, Issue 17, pp. 17286 - 17293
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 08/2003, Volume 278, Issue 31, pp. 28793 - 28798
Heterotrimeric G-proteins of the Galpha(12/13) family activate Rho GTPase through the guanine nucleotide exchange factor p115RhoGEF. Because Rho activation is... 
ACTIVATION | P115 RHOGEF | LYSOPHOSPHATIDIC ACID | BIOCHEMISTRY & MOLECULAR BIOLOGY | BARRIER FUNCTION | RECEPTOR | SHAPE CHANGE | FOCAL ADHESION KINASE | THROMBIN-INDUCED INCREASE | EXCHANGE FACTORS | RHO/RHO-KINASE
Journal Article
Journal Article
Biomicrofluidics, ISSN 1932-1058, 03/2017, Volume 11, Issue 2, p. 024102
The inflammatory response in endothelial cells (ECs) leads to an increase in vascular permeability through the formation of gaps. However, the dynamic nature... 
LIGHT-CHAIN KINASE | FLUID SHEAR-STRESS | PHYSICS, FLUIDS & PLASMAS | THERMAL-INJURY | BIOCHEMICAL RESEARCH METHODS | ENDOTHELIAL-CELL MONOLAYERS | BARRIER FUNCTION | DIFFUSION-COEFFICIENTS | NANOSCIENCE & NANOTECHNOLOGY | THROMBIN-INDUCED INCREASE | FLUORESCENCE RECOVERY | BIOPHYSICS | CYTOSKELETAL REORGANIZATION | TNF-ALPHA
Journal Article