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An Adenovirus Vector Containing the Suicide Gene Thymidine Kinase for a Broad Application in Cancer Gene Therapy, 12/2002
Treatment of cancer using gene therapy is based on adding a property to the cell leading to its elimination. One possibility is the use of suicide genes that... 
ganciclovir - adenovirus - thymidine kinase - cancer - gene therapy
Journal
03/2012
Fracture repair is a regenerative event that involves the precise coordination of a variety of cells for successful healing process. Within the microstructure... 
Chondrocyte | Gacnciclovir | Osteoblast | Endochondral Ossification | Osteoclast | Fracture repair | Herpes simplex virus thymidine kinase
Dissertation
Chemical communications (Cambridge, England), ISSN 1359-7345, 02/2017, Volume 53, Issue 16, pp. 2507 - 2510
Herein, we demonstrated a new gold nanoparticles (AuNPs)-integrated programmable triple-helix molecular switch (THMS) to realize the biosensing of multiple... 
Journal Article
Circulation. Cardiovascular imaging, 08/2018, Volume 11, Issue 8, p. e007402
Pulmonary vascular cell hyperproliferation is characteristic of pulmonary vascular remodeling in pulmonary arterial hypertension. A noninvasive imaging... 
thymidine kinase 1 | positron emission tomography | vascular remodeling | pulmonary hypertension
Journal Article
Organic Letters, ISSN 1523-7060, 12/2018, Volume 20, Issue 23, pp. 7400 - 7404
Two classes of azido-modified pyrimidine nucleosides were synthesized as potential radiosensitizers; one class is 5-azidomethyl-2'-deoxyuridine (AmdU) and... 
THYMIDINE KINASE | ABSTRACTION | ATTACHMENT | GENE | CLICK CHEMISTRY | DNA | REACTIVITY | RADIOSENSITIZERS | TRIPHOSPHATE | CHEMISTRY, ORGANIC | AZT
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 04/2005, Volume 102, Issue 15, pp. 5524 - 5529
Assessment of radiation and chemotherapy efficacy for brain cancer patients is traditionally accomplished by measuring changes in tumor size several months... 
THYMIDINE KINASE | PROGNOSTIC-FACTORS | RAT | MULTIDISCIPLINARY SCIENCES | therapeutic response | CANCER-THERAPY | MALIGNANT GLIOMA | RECTAL-CARCINOMA | WATER DIFFUSION | SPECTROSCOPY | IN-VIVO | diffusion MRI | CHEMORADIATION
Journal Article
by Li, MT and Liang, JY and Sun, YP and Jin, J and Xiong, Y and Guan, KL and Yuan, HX
BIOCHEMICAL JOURNAL, ISSN 0264-6021, 08/2019, Volume 476, Issue 15, pp. 2239 - 2254
Protein lysine acetylation is one of the major posttranslational modifications (PTMs) with several thousands of proteins identified to be acetylated in... 
THYMIDINE KINASE | PROTEIN | GENE | DEACETYLASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSCRIPTION | MUTATIONS | IDENTIFICATION | HISTONE ACETYLATION | ELONGATOR COMPLEX | PROTEOMICS
Journal Article
by Ou, M and Huang, J and Yang, XH and Quan, K and Yang, YJ and Xie, NL and Wang, KM
CHEMICAL SCIENCE, ISSN 2041-6520, 01/2017, Volume 8, Issue 1, pp. 668 - 673
The donor donor-acceptor (DD-A) FRET model has proven to have a higher FRET efficiency than donoracceptor acceptor (D-AA), donor-acceptor (D-A), and donor... 
BREAST-CANCER | THYMIDINE KINASE | PLATFORM | CELLS | FLUORESCENCE | NANOPROBE | NUCLEIC-ACID HYBRIDIZATION | DNA | RESONANCE ENERGY-TRANSFER | CHEMISTRY, MULTIDISCIPLINARY | Fretting | Efficiency | Imaging | Cells (biology) | Nanostructure | Diagnosis | Gene expression | Cancer
Journal Article
Antiviral Research, ISSN 0166-3542, 03/2018, Volume 151, pp. 20 - 23
We report the first application of ultra-deep sequencing (UDS) to varicella-zoster virus (VZV) genotypic antiviral testing in a case of acyclovir-resistant VZV... 
Minor variants | Thymidine kinase | Varicella-zoster virus | Ultra-deep sequencing | Antiviral resistance
Journal Article
Journal Article
Coordination Chemistry Reviews, ISSN 0010-8545, 10/2013, Volume 257, Issue 19-20, pp. 2689 - 2704
► Metallodrugs have various pharmacological applications in therapy or imaging. ► Proteins/enzymes are likely biological targets for metal compounds. ► The... 
Proteins | Therapeutic | Diagnostic | Mechanisms of action | Metal complexes | THYMIDINE KINASE | ION-CHANNEL FUNCTION | X-RAY-STRUCTURE | ZINC-FINGER | ORGANOMETALLIC TECHNETIUM | WATER PERMEABILITY | CHEMISTRY, INORGANIC & NUCLEAR | IN-VITRO | NITRIC-OXIDE | NUCLEAR PROTEINS | CARBONIC-ANHYDRASE INHIBITORS | Drugstores
Journal Article
Chinese Journal of Clinical Oncology, ISSN 1000-8179, 2018, Volume 45, Issue 9, pp. 445 - 448
Journal Article
Annales de Dermatologie et de Venereologie, ISSN 0151-9638, 03/2018, Volume 145, Issue 3, pp. 182 - 186
Background: Chronic HSV infection is a cause of chronic perineal ulcerations. We report a case of a chronic and refractory HSV infection revealing chronic... 
Thymidine kinase | Foscarnet | Acyclovir | Chronic ulceration | Herpes simplex virus
Journal Article
Nature, ISSN 0028-0836, 09/2011, Volume 477, Issue 7362, pp. 99 - 104
Journal Article