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BioEssays, ISSN 0265-9247, 2013, Volume 35, Issue 11, pp. 965 - 973
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 01/2014, Volume 124, Issue 1, pp. 367 - 384
There is a considerable resurgence of interest in the role of aerobic glycolysis in cancer; however, increased glycolysis is frequently viewed as a consequence... 
MEDICINE, RESEARCH & EXPERIMENTAL | GENE-EXPRESSION SIGNATURE | SOLUBLE ADENYLYL-CYCLASE | VIRUS-TRANSFORMED CELLS | GLUCOSE-METABOLISM | PYRUVATE-KINASE M2 | EPIDERMAL-GROWTH-FACTOR | RECONSTITUTED BASEMENT-MEMBRANE | EXTRACELLULAR-MATRIX | HUMAN BREAST CELLS | MAMMARY EPITHELIAL-CELLS | Up-Regulation | Humans | Glucose Transporter Type 3 - metabolism | Acetylglucosamine - metabolism | Breast Neoplasms - metabolism | Receptor, Epidermal Growth Factor - metabolism | Guanine Nucleotide Exchange Factors - metabolism | Female | Membrane Proteins - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Telomere-Binding Proteins - metabolism | Oncogenes | Second Messenger Systems | Cell Line | Oxygen Consumption | Biosynthetic Pathways | Glycosylation | MAP Kinase Kinase Kinases - metabolism | Adenylyl Cyclases - metabolism | Cell Transformation, Neoplastic - metabolism | Integrin beta1 - metabolism | Phenotype | Carrier Proteins - metabolism | Thyroid Hormones - metabolism | Glucose - metabolism | Glycolysis | Breast Neoplasms - mortality | Protein Processing, Post-Translational | Complications and side effects | Care and treatment | Patient outcomes | Physiological aspects | Development and progression | Research | Carcinogenesis | Risk factors | Integrins | Medical research | Dehydrogenases | Metabolites | Cloning | Breast cancer | Glucose | Metabolism | Gene expression
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/2014, Volume 111, Issue 1, pp. 279 - 284
Journal Article
Journal Article
Molecular cell, ISSN 1097-2765, 2012, Volume 48, Issue 5, pp. 771 - 784
Many types of human tumor cells have overexpressed pyruvate kinase M2 (PKM2). However, the mechanism underlying this increased PKM2 expression remains to be... 
GROWTH-FACTOR RECEPTOR | PROTEIN-KINASE-C | PYRUVATE-KINASE | UBIQUITIN LIGASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | ALPHA | BETA-CATENIN | TUMOR-GROWTH | TRANSCRIPTIONAL REGULATION | CANCER | CELL BIOLOGY | Receptor, Epidermal Growth Factor - genetics | Up-Regulation | Glioblastoma - enzymology | Humans | NF-kappa B - metabolism | Ubiquitination | Glioblastoma - genetics | RNA Interference | Cell Transformation, Neoplastic - genetics | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Signal Transduction | Membrane Proteins - genetics | Lactic Acid - metabolism | Protein Kinase C-epsilon - genetics | Brain Neoplasms - genetics | Polypyrimidine Tract-Binding Protein - metabolism | Mice, Nude | Glioblastoma - pathology | Protein Kinase C-epsilon - metabolism | Cell Line, Tumor | Glucose - metabolism | Mice | Enzyme Activation | Mutation | Neoplasm Transplantation | Phosphorylation | Prognosis | Serine | Brain Neoplasms - pathology | Gene Expression Regulation, Neoplastic | Receptor, Epidermal Growth Factor - metabolism | Neoplasm Grading | Transfection | I-kappa B Kinase - metabolism | HEK293 Cells | Female | Membrane Proteins - metabolism | Genes, Reporter | Promoter Regions, Genetic | Brain Neoplasms - enzymology | Phospholipase C gamma - metabolism | Mutagenesis, Site-Directed | Heterogeneous-Nuclear Ribonucleoproteins - metabolism | Epidermal Growth Factor - metabolism | Thyroid Hormones - genetics | Cell Transformation, Neoplastic - metabolism | Gene Expression Regulation, Enzymologic | Carrier Proteins - genetics | Animals | Carrier Proteins - metabolism | NF-kappa B - genetics | Transcription Factor RelA - metabolism | Thyroid Hormones - metabolism | Glycolysis | Cell Transformation, Neoplastic - pathology
Journal Article
Aquatic toxicology, ISSN 0166-445X, 2012, Volume 110-111, pp. 141 - 148
.... ► Bioaccumulation and metabolism of BDE-209 were evident. ► HPT axis can be used for testing endocrine disruption of THs by BDE-209, a higher PBDE congener... 
Thyroid endocrine disruption | Zebrafish larvae | Hypothalamic–Pituitary–Thyroid axis | Bioconcentration and metabolism | BDE-209 | Gene transcription | Hypothalamic-Pituitary-Thyroid axis | SPRAGUE-DAWLEY RATS | TRANSTHYRETIN | PBDES | POLYBROMINATED DIPHENYL ETHERS | HORMONE RECEPTORS | BIOACCUMULATION | PEARL RIVER DELTA | MARINE & FRESHWATER BIOLOGY | LIVER | TOXICOLOGY | DEVELOPMENTAL EXPOSURE | POLYCHLORINATED-BIPHENYLS | Up-Regulation | Thyrotropin - genetics | Embryo, Nonmammalian - metabolism | RNA, Messenger - metabolism | Zebrafish - embryology | Embryo, Nonmammalian - drug effects | Thyroid Hormone Receptors beta - genetics | Halogenated Diphenyl Ethers - toxicity | Triiodothyronine - metabolism | Triiodothyronine - genetics | Endocrine System - metabolism | Iodide Peroxidase - metabolism | Endocrine System - drug effects | Thyroid Gland - drug effects | Thyroid Hormone Receptors beta - metabolism | Endocrine Disruptors - metabolism | Thyrotropin - metabolism | Endocrine Disruptors - toxicity | Halogenated Diphenyl Ethers - metabolism | Water Pollutants, Chemical - metabolism | Animals | Water Pollutants, Chemical - toxicity | Thyroxine - metabolism | Thyroxine - genetics | Iodide Peroxidase - genetics | Thyroid Gland - metabolism | Corticotropin releasing hormone | Pituitary hormones | Genes | Physiological aspects | ACTH | Glycoproteins | Genetic transcription | Thyroid hormones | Hormones
Journal Article
Science (American Association for the Advancement of Science), ISSN 1095-9203, 2013, Volume 342, Issue 6155, pp. 1242454 - 1242454
Journal Article