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1. Full Text Dietary Exposure to 2,2',4,4'-Tetrabromodiphenyl Ether (PBDE-47) Alters Thyroid Status and Thyroid Hormone: Regulated Gene Transcription in the Pituitary and Brain
by Sean C. Lema and Jon T. Dickey and Irvin R. Schultz and Penny Swanson
Environmental Health Perspectives, ISSN 0091-6765, 12/2008, Volume 116, Issue 12, pp. 1694 - 1699
Background: Polybrominated diphenyl ether (PBDE) flame retardants have been implicated as disruptors of the hypothalamic-pituitary-thyroid axis. Animals... 
Minnows | Brain | Receptors | Messenger RNA | Halogenated diphenyl ethers | Genes | Liver | Thyroid hormones | Research | Dosage | Neurogenesis | Polybrominated diphenyl ethers | Thyroid-stimulating hormone | Basic transcription element-binding protein | Endocrine disruption | Thyroid hormone | Thyrotropin | PBDE-47 | Thyroid hormone receptor | thyroid hormone | MINNOW PIMEPHALES-PROMELAS | polybrominated diphenyl ethers | basic transcription element-binding protein | ELEMENT-BINDING PROTEIN | brain | endocrine disruption | thyroid-stimulating hormone | ADULT-RAT BRAIN | XENOPUS-LAEVIS | ENVIRONMENTAL SCIENCES | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | thyroid hormone receptor | thyrotropin | BROMINATED FLAME RETARDANTS | RECEPTOR-BETA | CENTRAL-NERVOUS-SYSTEM | FATHEAD MINNOW | POLYCHLORINATED-BIPHENYLS | Pituitary Gland - metabolism | Liver - metabolism | RNA, Messenger - genetics | Male | Brain - drug effects | Brain - metabolism | Halogenated Diphenyl Ethers - toxicity | Tissue Distribution | Halogenated Diphenyl Ethers - administration & dosage | Thyroid Gland - physiology | Transcription, Genetic - physiology | Animals | Receptors, Thyroid Hormone - genetics | Diet | Radioimmunoassay | Halogenated Diphenyl Ethers - pharmacokinetics | Female | Polybrominated Biphenyls | Cyprinidae | Pituitary Gland - drug effects | Thyroid Gland - drug effects | Thyroid Hormones - physiology | Polybrominated biphenyls | Environmental aspects | Physiological aspects | Thyroid gland | Genetic aspects | Gene expression | Health aspects | Index Medicus
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2. Full Text Thyroid-stimulating hormone, thyroid hormones, and risk of papillary thyroid cancer: A nested case-control study
by Huang, Huang and Rusiecki, Jennifer and Zhao, Nan and Chen, Yingtai and Ma, Shuangge and Yu, Herbert and Ward, Mary H and Udelsman, Robert and Zhang, Yawei
Cancer Epidemiology Biomarkers and Prevention, ISSN 1055-9965, 08/2017, Volume 26, Issue 8, pp. 1209 - 1218
Background: The effects of thyroid-stimulating hormone (TSH) and thyroid hormones on the development of human papillary thyroid cancer (PTC) remain poorly... 
COMMON VARIANTS | MALIGNANCY | NODULES | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | SERUM THYROTROPIN CONCENTRATION | RADIATION-EXPOSURE | ONCOLOGY | THYROGLOBULIN | TSH | POOLED ANALYSIS | CARCINOMA | TUMOR STAGE | Carcinoma, Papillary - epidemiology | Humans | Middle Aged | Thyroid Neoplasms - epidemiology | Adult | Female | Male | Thyrotropin - metabolism | Case-Control Studies | Thyroid Cancer, Papillary | Papillary thyroid cancer | Physicians | Risk | Population studies | Thyroid gland | Hormones | Confidence intervals | Regression models | Thyroxine | Bioindicators | Triiodothyronine | Thyroid hormones | Thyroid | Medical personnel | Women | Statistical analysis | Health risks | Regression analysis | Thyroidectomy | Laboratory tests | Thyroid-stimulating hormone | Thyroid cancer | Men | Biomarkers | Health risk assessment | Cancer | thyroid-stimulating hormone | thyroid hormone | papillary thyroid cancer
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3. Full Text Receptors for thyrotropin-releasing hormone, thyroid-stimulating hormone, and thyroid hormones in the macaque uterus: effects of long-term sex hormone treatment
by Hulchiy, Mariana and Zhang, Hua and Cline, J Mark and Hirschberg, Angelica Lindén and Sahlin, Lena
Menopause: The Journal of The North American Menopause Society, ISSN 1072-3714, 11/2012, Volume 19, Issue 11, pp. 1253 - 1259
OBJECTIVEThyroid gland dysfunction is associated with menstrual cycle disturbances, infertility, and increased risk of miscarriage, but the mechanisms are... 
Macaque | Uterus | Thyroid hormone receptor β | Thyrotropin-releasing hormone receptor | Thyroid hormone receptor A | Thyroid-stimulating hormone receptor | CONJUGATED EQUINE ESTROGENS | Thyroid hormone receptor beta | MEDROXYPROGESTERONE ACETATE | HUMAN-TISSUES | HUMAN-ENDOMETRIUM | MYOMETRIUM | OBSTETRICS & GYNECOLOGY | Thyroid hormone receptor alpha | REPRODUCTIVE-TRACT | CYNOMOLGUS MONKEYS | MICE | TIBOLONE | EXPRESSION | Receptors, Thyroid Hormone - drug effects | Norpregnenes - administration & dosage | Uterus - chemistry | Estrogens, Conjugated (USP) - administration & dosage | Gonadal Steroid Hormones - pharmacology | Macaca fascicularis | Receptors, Thyrotropin - drug effects | Receptors, Thyrotropin - analysis | Receptors, Thyrotropin-Releasing Hormone - analysis | Thyroid Hormone Receptors alpha - drug effects | Receptors, Thyroid Hormone - analysis | Animals | Thyroid Hormone Receptors alpha - analysis | Uterus - physiology | Thyroid Hormone Receptors beta - analysis | Thyroid Hormone Receptors beta - drug effects | Female | Medroxyprogesterone Acetate - administration & dosage | Immunohistochemistry - veterinary | Receptors, Thyrotropin-Releasing Hormone - drug effects
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4. Full Text Neuronostatin exerts actions on pituitary that are unique from its sibling peptide somatostatin
by Luque, Raúl M and Kineman, Rhonda D
Journal of Endocrinology, ISSN 0022-0795, 06/2018, Volume 237, Issue 3, pp. 217 - 227
Neuronostatin, a somatostatin gene-encoded peptide, exerts important physiological and metabolic actions in diverse tissues. However, the direct biological... 
Signaling pathways | GPCR107 | Primates | Growth hormone and luteinizing hormone | Somatostatin | Somatotrope and gonadotrope cells | Neuronostatin | somatotrope and gonadotrope cells | primates | HUMAN-DISEASE | GHRELIN | growth hormone and luteinizing hormone | NONHUMAN PRIMATE MODEL | IN-VITRO REGULATION | signaling pathways | PAPIO-ANUBIS | RECEPTOR SUBTYPES | GROWTH-HORMONE | MESSENGER-RNA | somatostatin | ENDOCRINOLOGY & METABOLISM | neuronostatin | SECRETION | HORMONE (GH)-RELEASING HORMONE | Peptide Hormones - pharmacology | Humans | Cells, Cultured | Structure-Activity Relationship | Papio anubis | Somatostatin - pharmacology | Animals | Substrate Specificity - drug effects | Female | Peptide Hormones - chemistry | Somatostatin - chemistry | Pituitary Gland - drug effects | Pituitary Gland - physiology | Protein kinase A | Protein kinase C | Proopiomelanocortin | Kinases | Hormone release | Prolactin | Ghrelin | Luteinizing hormone | Thyroid | Follicle-stimulating hormone | Calcium (intracellular) | Secretion | MAP kinase | Pituitary (anterior) | Gene expression | 1-Phosphatidylinositol 3-kinase | Phospholipase C | Phospholipase | Thyroid-stimulating hormone | Adrenocorticotropic hormone | Molecular modelling | Pituitary | Gonadotropin-releasing hormone | Growth hormone
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5. Full Text Application of antibody–nanogold–ionic liquid–carbon paste electrode for sensitive electrochemical immunoassay of thyroid-stimulating hormone
by Beitollahi, Hadi and Ivari, Susan Ghofrani and Torkzadeh-Mahani, Masoud
Biosensors and Bioelectronics, ISSN 0956-5663, 07/2018, Volume 110, pp. 97 - 102
A novel electrochemical immunosensor based on carbon paste electrode (CPE) composed of ionic liquid (IL) and graphite was constructed. It demonstrated good... 
O-Aminophenol | Thyroid stimulating hormone | Electrochemical immunoassay | Carbon paste electrode | Gold nanoparticle | Ionic liquid | GOLD NANOPARTICLES | ELECTROCHEMISTRY | AMPEROMETRIC IMMUNOSENSOR | CHEMISTRY, ANALYTICAL | GRAPHENE | SENSOR | NANOSCIENCE & NANOTECHNOLOGY | CARE | ENZYME | BIOPHYSICS | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | CHEMILUMINESCENCE IMMUNOASSAY | NANOCOMPOSITE | POINT | PROSPECTS
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6. Full Text Thyroid Hormone Therapy for Older Adults with Subclinical Hypothyroidism
by Stott, David J and Rodondi, Nicolas and Kearney, Patricia M and Ford, Ian and Westendorp, Rudi G.J and Mooijaart, Simon P and Sattar, Naveed and Aubert, Carole E and Aujesky, Drahomir and Bauer, Douglas C and Baumgartner, Christine and Blum, Manuel R and Browne, John P and Byrne, Stephen and Collet, Tinh-Hai and Dekkers, Olaf M and den Elzen, Wendy P.J and Du Puy, Robert S and Ellis, Graham and Feller, Martin and Floriani, Carmen and Hendry, Kirsty and Hurley, Caroline and Jukema, J. Wouter and Kean, Sharon and Kelly, Maria and Krebs, Danielle and Langhorne, Peter and McCarthy, Vera and McCarthy, Gemma and McConnachie, Alex and McDade, Mairi and Messow, Martina and O’Flynn, Annemarie and O’Riordan, David and Poortvliet, Rosalinde K.E and Quinn, Terence J and Russell, Audrey and Sinnott, Carol and Smit, Jan W.A and Van Dorland, H. Anette and Walsh, Elaine K and Walsh, Kieran A and Watt, Torquil and Wilson, Robbie and Gussekloo, Jacobijn and TRUST Study Grp and TRUST Study Group
The New England Journal of Medicine, ISSN 0028-4793, 06/2017, Volume 376, Issue 26, pp. 2534 - 2544
A double-blind, randomized, placebo-controlled, parallel-group trial aimed to determine whether levothyroxine provided clinical benefits in older persons with... 
REPLACEMENT | MORTALITY | CONTROLLED-TRIAL | MEDICINE, GENERAL & INTERNAL | LEVOTHYROXINE TREATMENT | DISEASE | THYROXINE | QUALITY-OF-LIFE | PREVALENCE | COGNITIVE FUNCTION | THYPRO | Double-Blind Method | Humans | Hypothyroidism - complications | Thyroxine - administration & dosage | Fatigue - etiology | Thyroxine - blood | Male | Thyroxine - adverse effects | Treatment Failure | Hypothyroidism - drug therapy | Intention to Treat Analysis | Aged, 80 and over | Quality of Life | Female | Aged | Thyrotropin - blood | Body weight | Clinical trials | Thyroid gland | Hypothyroidism | Epidemiology | Coronary artery disease | Quality of life | Thyroid-stimulating hormone | Older people | Thyroxine | Drug therapy | Heart diseases | Drug dosages | Endocrinology | Age | Thyroid
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7. Full Text Alterations in Hypothalamus-Pituitary-Adrenal/Thyroid Axes and Gonadotropin-Releasing Hormone in the Patients with Primary Insomnia: A Clinical Research
by Xia, Lan and Chen, Gui-Hai and Li, Zhi-Hua and Jiang, Song and Shen, Jianhua
PLoS ONE, ISSN 1932-6203, 08/2013, Volume 8, Issue 8, p. e71065
The hypothalamus-pituitary-target gland axis is thought to be linked with insomnia, yet there has been a lack of further systematic studies to prove this. This... 
STRESS SYSTEM | SLEEP DISORDERS | NOCTURNAL CORTISOL | MULTIDISCIPLINARY SCIENCES | NEURONS | MAJOR DEPRESSIVE DISORDER | ADRENAL AXIS | SECRETION | DYSFUNCTION | POSTMENOPAUSAL WOMEN | HPA-AXIS | Pituitary-Adrenal System - physiopathology | Pituitary-Adrenal System - metabolism | Humans | Middle Aged | Thyroxine - blood | Corticotropin-Releasing Hormone - blood | Male | Gonadotropin-Releasing Hormone - blood | Case-Control Studies | Hypothalamo-Hypophyseal System - metabolism | Sleep Initiation and Maintenance Disorders - blood | Thyrotropin-Releasing Hormone - blood | Triiodothyronine - blood | Adult | Female | Sleep Initiation and Maintenance Disorders - physiopathology | Hydrocortisone - blood | Thyroid Gland - metabolism | Hypothalamo-Hypophyseal System - physiopathology | Adrenocorticotropic Hormone - blood | Thyroid Gland - physiopathology | Thyrotropin - blood | Medical research | Corticosteroids | Insomnia | Thyroxine | ACTH | Clinical trials | Medicine, Experimental | Glycoproteins | Research | Hormones | Morning | Bipolar disorder | Thyroid gland | Mental depression | Hypothalamus | Family medical history | Eye movements | Hydrocortisone | Sleep disorders | Regression models | Alterations | Triiodothyronine | Thyroid hormones | Thyroid | Thyrotropin-releasing hormone | Gonadotropins | Pituitary (anterior) | Regression analysis | Gene expression | Hypothyroidism | Corticotropin-releasing hormone | Releasing | Patients | Studies | Restless legs syndrome | Neurology | Thyroid-stimulating hormone | Brain research | Hospitals | Sleep | Adrenocorticotropic hormone | Correlation analysis | Womens health | Pituitary | Gonadotropin-releasing hormone | Psychiatry | Endocrinology
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8. Full Text Evaluation of small-molecule modulators of the luteinizing hormone/choriogonadotropin and thyroid stimulating hormone receptors: Structure-activity relationships and selective binding patterns
by Moore, Susanna and Jaeschke, Holger and Kleinau, Gunnar and Neumann, Susanne and Costanzi, Stefano and Jiang, Jian-Kang and Childress, John and Raaka, Bruce M and Colson, Anny and Paschke, Ralf and Krause, Gerd and Thomas, Craig J and Gershengorn, Marvin C
Journal of Medicinal Chemistry, ISSN 0022-2623, 06/2006, Volume 49, Issue 13, pp. 3888 - 3896
The substituted thieno[ 2,3-d] pyrimidine 3 ( Org 41841), a partial agonist for the luteinizing hormone/choriogonadotropin receptor ( LHCGR) and the closely... 
CHEMISTRY, MEDICINAL | IDENTIFICATION | ANTAGONISTS | AGONISTS | Chorionic Gonadotropin - agonists | Luteinizing Hormone - agonists | Receptors, Thyrotropin - agonists | Pyrimidines - chemical synthesis | Models, Molecular | Structure-Activity Relationship | Pyrimidines - chemistry | Thiophenes - chemical synthesis | Chorionic Gonadotropin - chemistry | Hydrogen Bonding | Ligands | Luteinizing Hormone - chemistry | Receptors, Thyrotropin - chemistry | Thiophenes - chemistry | Binding Sites | Luteinizing Hormone | Org 41841 | Thyroid Stimulating Hormone Receptor | Choriogonadotropin Receptor
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9. Full Text Permanent congenital hypothyroidism with blood spot thyroid stimulating hormone <10 mU/L
by Jones, Jeremy H and Smith, Sarah and Dorrian, Catherine and Mason, Avril and Shaikh, M Guftar
Archives of Disease in Childhood, ISSN 0003-9888, 01/2018, Volume 103, Issue 1, pp. 65 - 67
BackgroundThe UK recommended lower threshold for neonatal blood spot thyroid stimulating hormone (TSH) screening for congenital hypothyroidism (CHT) is 10.0... 
ULTRASOUND | NEWBORN | PEDIATRICS | Congenital Hypothyroidism - diagnosis | Humans | Female | Infant | Male | Reference Values | United Kingdom | Neonatal Screening - methods | Referral and Consultation | Infant, Newborn | Thyrotropin - blood | Thyrotropin | Care and treatment | Usage | Research | Thyroid gland function tests | Congenital hypothyroidism | Neonates | Pediatrics | Congenital diseases | Laboratories | Infants | Thyroid gland | Hypothyroidism | Medical screening | Blood | Children & youth | Thyroid-stimulating hormone | Audits | Ultrasonic imaging | Newborn babies | Thyroxine | Birth weight | Age | Endocrinology | Thyroid
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10. Full Text Aminoaciduria, but normal thyroid hormone levels and signalling, in mice lacking the amino acid and thyroid hormone transporter Slc7a8
by Braun, Doreen and Wirth, Eva K and Wohlgemuth, Franziska and Reix, Nathalie and Klein, Marc O and Grüters, Annette and Köhrle, Josef and Schweizer, Ulrich
Biochemical Journal, ISSN 0264-6021, 10/2011, Volume 439, Issue 2, pp. 249 - 255
LAT2 (system L amino acid transporter 2) is composed of the subunits Slc7a8/Lat2 and Slc3a2/4F2hc. This transporter is highly expressed along the basolateral... 
Brain | Thyroid-stimulating hormone (TSH) | Monocarboxylate transporter 8 (Mct8) | System L amino acid transporter 2 (Lat2) | 3,3′,5,5′-tetra-iodo-L-thyronine (T | 3,5,5′-tri-iodo-Lthyronine (T | HERNDON-DUDLEY-SYNDROME | LYSINURIC PROTEIN INTOLERANCE | BIOCHEMISTRY & MOLECULAR BIOLOGY | 3,5,5'-tri-iodo-L-thyronine(T-3) | MONOCARBOXYLATE TRANSPORTER-8 | brain | IDENTIFICATION | system L amino acid transporter 2 (Lat2) | thyroid-stimulating hormone (TSH) | HEAVY-CHAIN | 3,3',5,5'-tetra-iodo-L-thyronine (T-4) | METABOLISM | GENE | monocarboxylate transporter 8 (Mct8) | DEIODINASE | KIDNEY | Immunohistochemistry | Signal Transduction | Mice, Inbred C57BL | Amino Acid Transport System y+ - genetics | Brain - growth & development | Fusion Regulatory Protein 1, Light Chains - genetics | DNA Primers | Amino Acid Metabolism, Inborn Errors - blood | Blotting, Western | Mice, Knockout | Amino Acid Transport System y+ - metabolism | Animals | Fusion Regulatory Protein 1, Light Chains - metabolism | Thyroid Hormones - blood | Base Sequence | Polymerase Chain Reaction | Mice
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11. Full Text Fasting serum glucose, thyroid‐stimulating hormone, and thyroid hormones and risk of papillary thyroid cancer: A case‐control study
by Hu, Ming‐Jun and Zhang, Chi and Liang, Ling and Wang, Sheng‐Ying and Zheng, Xu‐Cai and Zhang, Qian and Jiang, Chun‐Xiao and Zhong, Qi and Huang, Fen
Head & Neck, ISSN 1043-3074, 07/2019, Volume 41, Issue 7, pp. 2277 - 2284
Background This study was to investigate the association of fasting serum glucose (FSG), thyroid-stimulating hormone (TSH), and thyroid hormones with papillary... 
TSH | glucose | thyroid‐stimulating hormone | thyroid hormone | papillary thyroid cancer | thyroid-stimulating hormone | MORTALITY | SURGERY | STATISTICS | TRENDS | FRANCE | THYROTROPIN | WOMEN | METABOLISM | OTORHINOLARYNGOLOGY | NODULE | ASSOCIATION | CARCINOMA | Fasting | Thyroid cancer | Oncology, Experimental | Thyroxine | Thyrotropin | Glucose | Research | Health aspects | Risk factors | Dextrose | Cancer | Thyroid-stimulating hormone | Papillary thyroid cancer | Diabetes mellitus | Triiodothyronine | Thyroid hormones | Hormones | Health risk assessment | Thyroid
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12. Full Text Association of Thyroid Hormone Therapy With Quality of Life and Thyroid-Related Symptoms in Patients With Subclinical Hypothyroidism: A Systematic Review and Meta-analysis
by Feller, Martin and Feller, Martin and Snel, Marieke and Snel, Marieke and Moutzouri, Elisavet and Moutzouri, Elisavet and Bauer, Douglas C and Bauer, Douglas C and de Montmollin, Maria and Aujesky, Drahomir and Ford, Ian and Gussekloo, Jacobijn and Kearney, Patricia M and Kearney, Patricia M and Mooijaart, Simon and Quinn, Terry and Stott, David and Westendorp, Rudi and Rodondi, Nicolas and Dekkers, Olaf M
JAMA, ISSN 0098-7484, 10/2018, Volume 320, Issue 13, pp. 1349 - 1359
IMPORTANCE The benefit of thyroid hormone therapy for subclinical hypothyroidism is uncertain. New evidence from recent large randomized clinical trials... 
INTIMA-MEDIA THICKNESS | CLINICAL ENDOCRINOLOGISTS | CARDIAC-FUNCTION | CONTROLLED-TRIAL | MEDICINE, GENERAL & INTERNAL | LEVOTHYROXINE REPLACEMENT | AMERICAN ASSOCIATION | DOUBLE-BLIND | L-THYROXINE THERAPY | ENDOTHELIAL FUNCTION | COGNITIVE FUNCTION | Thyroxine - adverse effects | Humans | Hypothyroidism - complications | Hypothyroidism - drug therapy | Quality of Life | Adult | Blood Pressure - drug effects | Thyroxine - therapeutic use | Hypothyroidism - blood | Practice Guidelines as Topic | Thyrotropin - blood | Medical research | Therapy | Bias | Endocrine therapy | Clinical trials | Systematic review | Thyroid gland | Hypothyroidism | Quality of life | Meta-analysis | Thyroid-stimulating hormone | Randomization | Synthesis | Risk assessment | Adults | Quality assessment | Thyroid | Original Investigation | Research
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13. Full Text Arsenic in seafood is associated with increased thyroid-stimulating hormone (TSH) in healthy volunteers – A randomized controlled trial
by Molin, M and Ulven, S.M and Dahl, L and Lundebye, A.-K and Holck, M and Alexander, J and Meltzer, H.M and Ydersbond, T.A
Journal of Trace Elements in Medicine and Biology, ISSN 0946-672X, 12/2017, Volume 44, pp. 1 - 7
Exposure to exogenous elements like arsenic (As) may influence thyroid enzymes, thyroid-stimulating hormone (TSH), and the two principal thyroid hormones, free... 
Arsenic in seafood | Thyroid-stimulating hormone | Dietary intervention | Arsenic | Randomized controlled trial | Iodine | BIOCHEMISTRY & MOLECULAR BIOLOGY | URINARY-EXCRETION | FOODS | SELENIUM | ENDOCRINOLOGY & METABOLISM | MUSSELS MYTILUS-EDULIS | EXPOSURE | SPECTROMETRY | Selenium - blood | Triiodothyronine - blood | Multivariate Analysis | Humans | Thyroxine - blood | Female | Male | Arsenic - analysis | Healthy Volunteers | Seafood - analysis | Iodine - urine | Thyrotropin - blood | Seafood | Thyrotropin | Enzymes | Analysis | Thyroxine | Thyroid gland
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14. Full Text TRH action is impaired in pituitaries of male IGSF1-deficient mice
by Turgeon, Marc-Olivier and Silander, Tanya L and Doycheva, Denica and Liao, Xiao-Hui and Rigden, Marc and Ongaro, Luisina and Zhou, Xiang and Joustra, Sjoerd D and Wit, Jan M and Wade, Mike G and Heuer, Heike and Refetoff, Samuel and Bernard, Daniel J
Endocrinology, ISSN 0013-7227, 04/2017, Volume 158, Issue 4, pp. 815 - 830
Loss-of-function mutations in the X-linked immunoglobulin superfamily, member 1 (IGSF1) gene cause central hypothyroidism. IGSF1 is a transmembrane... 
RECEPTOR 1-DEFICIENT MICE | CONGENITAL CENTRAL HYPOTHYROIDISM |