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American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 2012, Volume 302, Issue 1, pp. H215 - H223
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 02/2018, Volume 115, Issue 6, pp. 1298 - 1303
Journal Article
11/2009
Tie2 is a receptor tyrosine kinase (RTK) involved in numerous aspects of both normal and pathological angiogenesis. Proper functioning of this receptor is... 
0379 | Tie2 | signal transduction | 0307
Dissertation
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 02/2007, Volume 104, Issue 9, pp. 3243 - 3248
Journal Article
NEUROSCIENCE RESEARCH, ISSN 0168-0102, 10/2019, Volume 147, pp. 1 - 8
Angiopoietin-1 (Ang1) and its receptor Tie2 regulate vascular function. Our previous study demonstrated that thymosin beta 4 (T beta 4) ameliorates... 
COMP-ANGIOPOIETIN-1 | ANGIOGENESIS | TIE2 | RECEPTOR | BLOOD-FLOW | NEUROSCIENCES | Anti-Tie2 | DEGENERATION | Mouse | Diabetic peripheral neuropathy | ENDOTHELIAL-CELLS | NEUROGENESIS | PROMOTES | Thymosin beta 4 | VASCULAR FACTORS
Journal Article
International Journal of Pharmaceutics, ISSN 0378-5173, 05/2010, Volume 391, Issue 1-2, pp. 155 - 161
Tumor angiogenesis is a prominent mechanism, driving the development and progression of solid tumors and the formation of cancer cell metastasis. Newly formed... 
VEGFR2 | Angiogenesis | Adenovirus | Tie2 | Integrins
Journal Article
Neuroscience Research, ISSN 0168-0102, 10/2019, Volume 147, pp. 1 - 8
Angiopoietin-1 (Ang1) and its receptor Tie2 regulate vascular function. Our previous study demonstrated that thymosin beta 4 (Tβ4) ameliorates neurological... 
Mouse | Diabetic peripheral neuropathy | Thymosin β4 | Anti-Tie2
Journal Article
Frontiers in Physiology, ISSN 1664-042X, 2014, Volume 5, p. 75
Tumor angiogenesis is an essential process for supplying rapidly growing malignant tissues with essential nutrients and oxygen. An angiogenic switch allows... 
Stabilin-1 | TIE2 receptor | VEGF | LYVE-1 | Tumor-associated macrophages | Chitinase-like protein | tumour-associated macrophages | Angiogenesis | chitinase-like protein | Lymphangiogenesis
Journal Article
CANCER CELL, ISSN 1535-6108, 12/2004, Volume 6, Issue 6, pp. 553 - 563
The recent landmark Phase III clinical trial with a VEGF-specific antibody suggests that antiangiogenic therapy must be combined with cytotoxic therapy for the... 
ANGIOGENESIS | ONCOLOGY | IN-VIVO | BLOOD-VESSELS | ANTIBODY | CELL APOPTOSIS | IONIZING-RADIATION | CANCER | ENDOTHELIAL GROWTH-FACTOR | BASEMENT-MEMBRANE | TIE2 RECEPTOR
Journal Article
Critical Care Medicine, ISSN 0090-3493, 07/2018, Volume 46, Issue 9, pp. e928 - e936
OBJECTIVES:Tie2 is a tyrosine kinase receptor expressed by endothelial cells that maintains vascular barrier function. We recently reported that diverse... 
MORTALITY | endothelium | PERMEABILITY | Tie2 | matrix metalloprotease 14 | shedding | ANGIOPOIETIN-2 | SOLUBLE TIE2 | angiopoietin | GATA binding protein 3 | MULTIPLE ORGAN DYSFUNCTION | GENE | INFLAMMATION | VASCULATURE | SEPTIC SHOCK | EXPRESSION | flow | CRITICAL CARE MEDICINE | Gene expression | Sepsis | Research | MMP14 | Angiopoietin | GATA3 | Endothelium
Journal Article
Cytokine and Growth Factor Reviews, ISSN 1359-6101, 2013, Volume 24, Issue 6, pp. 579 - 592
Journal Article
Molecular Syndromology, ISSN 1661-8769, 04/2013, Volume 4, Issue 4, pp. 179 - 183
Venous malformations (VMs) are the most frequent vascular malformations referred to specialized vascular anomaly centers. A rare (1-2%) familial form, termed... 
Original Article | Hyperphosphorylation | Somatic mutation | TIE2/TEK | Sporadic | Receptor tyrosine kinase | Vascular malformation | Venous malformation | TIE2 | TEK | Original
Journal Article
NATURE COMMUNICATIONS, ISSN 2041-1723, 01/2015, Volume 6
Angiopoietins regulate vascular homeostasis via the endothelial Tie receptor tyrosine kinases. Angiopoietin-1 (Ang1) supports endothelial stabilization via... 
SELECTIVE-INHIBITION | CELL-JUNCTIONS | ANGIOGENESIS | ALPHA-V-BETA-3 | MULTIDISCIPLINARY SCIENCES | VASCULAR LEAK | VE-CADHERIN | LUNG INJURY | TUMOR-GROWTH