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2017, Annals of the New York Academy of Sciences, Volume 1397., 230 pages
"Tight junctions between epithelial and endothelial cells form selective barriers. However, some tight junction proteins form ion or water channels that... 
Tight junctions (Cell biology)
Book
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 5/2003, Volume 161, Issue 3, pp. 653 - 660
Tight junctions are well-developed between adjacent endothelial cells of blood vessels in the central nervous system, and play a central role in establishing... 
Brain | Tight junctions | Central nervous system | Reagents | Blood vessels | Mice | Cell membranes | Blood brain barrier | Embryos | Endothelial cells | Tight junction | Drug delivery | Blood vessel | DRUG | CLAUDIN | endothelial cells | blood vessel | MEMBRANE-PROTEIN | drug delivery | WATER PERMEABILITY | central nervous system | P-GLYCOPROTEIN | CELL BIOLOGY | TIGHT JUNCTION STRANDS | ADHESION MOLECULE | ENDOTHELIAL-CELLS | OCCLUDIN | tight junction | INTERCELLULAR-JUNCTIONS | Immunohistochemistry | Brain - embryology | Molecular Weight | Tight Junctions - genetics | Extracellular Space - drug effects | Male | Molecular Probes - pharmacology | Endothelium, Vascular - ultrastructure | Brain - blood supply | Membrane Proteins - deficiency | Extracellular Space - metabolism | Reaction Time - drug effects | Brain - ultrastructure | Female | Fetus | Fluorescent Dyes - pharmacology | Gadolinium DTPA - pharmacokinetics | Endothelium, Vascular - embryology | Tight Junctions - metabolism | Membrane Proteins - genetics | Neovascularization, Physiologic - genetics | Claudin-5 | Reaction Time - genetics | Microscopy, Electron | Blood-Brain Barrier - drug effects | Blood-Brain Barrier - genetics | Mice, Knockout | Tight Junctions - ultrastructure | Magnetic Resonance Imaging | Animals | Endothelium, Vascular - metabolism | Cardiovascular system | Nervous system | Blood-brain barrier | Cardiopulmonary system | tight junction; central nervous system; endothelial cells; blood vessel; drug delivery
Journal Article
Biochemical Pharmacology, ISSN 0006-2952, 10/2016, Volume 118, pp. 59 - 67
[Display omitted] Intestinal barrier injury has been reported to play a vital role in the pathogenesis of endotoxemia. This study aimed to investigate the... 
GYY4137 | Hydrogen sulfide | Tight junction | LPS | NF-kB | APOPTOSIS | EPITHELIAL BARRIER | ACTIVATION | MECHANISM | FACTOR-KAPPA-B | BACTERIAL TRANSLOCATION | PROTECTS | NF-kappa B | HYDROGEN-SULFIDE DONOR | PATHWAY | PHARMACOLOGY & PHARMACY | TIGHT JUNCTION PERMEABILITY | Organothiophosphorus Compounds - therapeutic use | Tumor Necrosis Factor-alpha - metabolism | Intestinal Mucosa - physiopathology | Tight Junction Proteins - genetics | Apoptosis - drug effects | Enterocytes - metabolism | Humans | Cell Membrane Permeability | Male | Endotoxemia - pathology | Interferon-gamma - metabolism | Lipopolysaccharides - antagonists & inhibitors | Protective Agents - therapeutic use | Organothiophosphorus Compounds - pharmacology | Intestinal Mucosa - drug effects | Intestinal Mucosa - immunology | Protective Agents - pharmacology | Endotoxemia - physiopathology | Endotoxemia - immunology | Interferon-gamma - antagonists & inhibitors | Morpholines - therapeutic use | Tight Junction Proteins - metabolism | Disease Models, Animal | Tight Junctions - drug effects | Caco-2 Cells | Tight Junctions - metabolism | Lipopolysaccharides - toxicity | Intestinal Mucosa - ultrastructure | Endotoxemia - drug therapy | Mice, Inbred C57BL | Morpholines - pharmacology | Electric Impedance | Random Allocation | Enterocytes - immunology | Gene Expression Regulation - drug effects | Tight Junctions - ultrastructure | Gastrointestinal Agents - pharmacology | Animals | Enterocytes - drug effects | Tight Junctions - immunology | Gastrointestinal Agents - therapeutic use | Enterocytes - ultrastructure | Tumor Necrosis Factor-alpha - antagonists & inhibitors
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 3/2002, Volume 156, Issue 6, pp. 1099 - 1111
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1, pp. 203 - 16
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 4/2010, Volume 107, Issue 17, pp. 8011 - 8016
Journal Article
Toxicological Sciences, ISSN 1096-6080, 11/2015, Volume 148, Issue 1, pp. 192 - 203
Gold nanoparticles (Au-NPs) are being increasingly used as constituents in cosmetics, biosensors, bioimaging, photothermal therapy, and targeted drug delivery.... 
blood-brain barrier | protein kinase C zeta (PKCζ) | Endothelial barrier | paracellular permeability | tight junction | CELL PERMEABILITY | PROTEIN | KINASE | endothelial barrier | PHOSPHORYLATES OCCLUDIN | CROSS-TALK | IN-VITRO | OXIDE NANOPARTICLES | protein kinase C zeta (PKC zeta) | VE-CADHERIN | TOXICOLOGY | ZETA PKC-ZETA | MOLECULAR-MECHANISMS | Endothelium, Vascular - cytology | Protein Kinase C - genetics | Tight Junction Proteins - genetics | Blood-Brain Barrier - cytology | Humans | Capillary Permeability - drug effects | Endothelium, Vascular - drug effects | Male | Drug Carriers | Proteasome Endopeptidase Complex - drug effects | Protein Processing, Post-Translational - drug effects | Protein Kinase C - metabolism | Phosphorylation - drug effects | Tight Junction Proteins - metabolism | Gold - toxicity | Metal Nanoparticles - ultrastructure | Tight Junctions - drug effects | Gold - chemistry | Tight Junctions - metabolism | Nerve Tissue Proteins - antagonists & inhibitors | Cells, Cultured | Protein Kinase C - antagonists & inhibitors | Blood-Brain Barrier - drug effects | Nerve Tissue Proteins - genetics | Mice, Inbred ICR | Tight Junction Proteins - antagonists & inhibitors | Gene Expression Regulation - drug effects | Nerve Tissue Proteins - metabolism | Particle Size | Toxicokinetics | Metal Nanoparticles - toxicity | Animals | Endothelium, Vascular - metabolism | Cell Line, Tumor | Proteasome Endopeptidase Complex - metabolism | Index Medicus
Journal Article
PLoS Pathogens, ISSN 1553-7366, 2014, Volume 10, Issue 6, p. e1004198
Effective antiretroviral therapy (ART) dramatically reduces AIDS-related complications, yet the life expectancy of long-term ART-treated HIV-infected patients... 
Ileum - pathology | Intestinal Mucosa - metabolism | Tight Junction Proteins - genetics | Colon, Ascending - metabolism | Humans | Middle Aged | Colon - drug effects | Colon, Transverse - drug effects | Tight Junctions - virology | Ileum - metabolism | Colon, Transverse - metabolism | Male | Intestinal Mucosa - drug effects | Ileum - drug effects | Colon, Descending - metabolism | HIV Infections - pathology | Colon, Descending - drug effects | Anti-HIV Agents - therapeutic use | Colon, Ascending - drug effects | Female | Colon - virology | Tight Junction Proteins - metabolism | Tight Junctions - drug effects | Tight Junctions - metabolism | Permeability - drug effects | Colon - pathology | Anti-HIV Agents - adverse effects | HIV Infections - virology | Colon, Ascending - virology | Intestinal Mucosa - virology | Academic Medical Centers | Colon, Transverse - virology | Down-Regulation - drug effects | Organ Specificity | Colon - metabolism | Tight Junction Proteins - antagonists & inhibitors | Ileum - virology | Colon, Descending - pathology | Colon, Transverse - pathology | HIV Infections - drug therapy | Ohio | Colon, Descending - virology | Colon, Ascending - pathology | Tight Junctions - pathology | Cohort Studies | HIV Infections - metabolism | Intestinal Mucosa - pathology | Antiviral agents | Highly active antiretroviral therapy | Care and treatment | AIDS (Disease) | HIV patients | Drug therapy | Health aspects | Life expectancy | Statistical analysis | Disease | AIDS | Infections | Permeability | Patients | Proteins | HIV | Acquired immune deficiency syndrome | Biopsy | Lymphocytes | Rodents | Human immunodeficiency virus | Viral infections | Immune system
Journal Article