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Clinical Therapeutics, ISSN 0149-2918, 2014, Volume 36, Issue 12, pp. 2072 - 2079
Abstract Purpose Although recent reports suggest an association between saxagliptin and an increased risk of admissions for heart failure, it is not clear... 
Internal Medicine | Medical Education | DPP-IV inhibition | cardiovascular disease | heart failure | type 2 diabetes | Examination of Cardiovascular Outcomes with Alogliptin versus Standard of Care (EXAMINE) | Vildagliptin in Ventricular Dysfunction Diabetes Trial (VIVIDD) | Saxagliptin Assessment of Vascular Outcomes Recorded in Patients with Diabetes Mellitus–Thrombolysis in Myocardial Infarction (SAVOR-TIMI) 53 trial | Saxagliptin Assessment of Vascular Outcomes Recorded in Patients with Diabetes Mellitus-Thrombolysis in Myocardial Infarction (SAVOR-TIMI) 53 trial | MYOCARDIAL-INFARCTION | SAXAGLIPTIN | HUMANS | Saxagliptin Assessment of Vascular Outcomes Recorded in Patients with Diabetes Mellitus Thrombolysis in Myocardial Infarction (SAVOR-TIMI) 53 trial | IMPACT | CLINICAL-TRIALS | IMPROVES | PHARMACOLOGY & PHARMACY | TYPE-2 DIABETES-MELLITUS | CARDIOVASCULAR RISK | Dipeptides - therapeutic use | Dipeptidyl-Peptidase IV Inhibitors - adverse effects | Dipeptides - adverse effects | Dipeptidyl-Peptidase IV Inhibitors - therapeutic use | Humans | Pyrrolidines - adverse effects | Uracil - therapeutic use | Hospitalization | Pyrrolidines - therapeutic use | Uracil - adverse effects | Piperidines - therapeutic use | Piperidines - adverse effects | Adamantane - therapeutic use | Sitagliptin Phosphate - therapeutic use | Diabetes Mellitus, Type 2 - drug therapy | Nitriles - adverse effects | Heart Failure - chemically induced | Adamantane - adverse effects | Adamantane - analogs & derivatives | Nitriles - therapeutic use | Sitagliptin Phosphate - adverse effects | Uracil - analogs & derivatives | Heart failure | Regulatory agencies | Heart attacks | Peptides | Mortality | Cardiovascular disease | FDA approval | Patients | Studies | Databases | Diabetes | Drug therapy | Acute coronary syndromes
Journal Article
JACC: Cardiovascular Interventions, ISSN 1936-8798, 2013, Volume 6, Issue 7, pp. 671 - 683
Objectives The PLATO (Platelet Inhibition and Patient Outcomes) angiographic substudy sought to compare the efficacy of ticagrelor versus clopidogrel with... 
Cardiovascular | clopidogrel | Thrombolysis in Myocardial Infarction | ticagrelor | TIMI myocardial perfusion grade | corrected TIMI frame count | CARDIAC & CARDIOVASCULAR SYSTEMS | ADENOSINE | P2Y RECEPTOR ANTAGONIST | PRIMARY PCI | ABCIXIMAB | ANTIPLATELET | TIMI FRAME COUNT | PERCUTANEOUS CORONARY INTERVENTION | ACUTE MYOCARDIAL-INFARCTION | Coronary Vessels - diagnostic imaging | Predictive Value of Tests | Ticlopidine - therapeutic use | Coronary Vessels - physiopathology | Humans | Middle Aged | Acute Coronary Syndrome - physiopathology | Male | Coronary Thrombosis - physiopathology | Myocardial Perfusion Imaging | Coronary Thrombosis - diagnostic imaging | Coronary Stenosis - prevention & control | Time Factors | Adenosine - therapeutic use | Platelet Aggregation Inhibitors - administration & dosage | Coronary Thrombosis - prevention & control | Ticlopidine - administration & dosage | Female | Platelet Aggregation Inhibitors - therapeutic use | Coronary Circulation | Coronary Stenosis - diagnostic imaging | Coronary Vessels - drug effects | Double-Blind Method | Administration, Oral | Acute Coronary Syndrome - diagnostic imaging | Logistic Models | Treatment Outcome | Adenosine - administration & dosage | Ticlopidine - analogs & derivatives | Coronary Angiography | Adenosine - analogs & derivatives | Coronary Stenosis - physiopathology | Acute Coronary Syndrome - therapy | Aged | Percutaneous Coronary Intervention - adverse effects
Journal Article
Journal of the American College of Cardiology, ISSN 0735-1097, 2014, Volume 63, Issue 13, pp. 1278 - 1288
Journal Article
Stroke, ISSN 0039-2499, 09/2013, Volume 44, Issue 9, pp. 2650 - 2663
Journal Article
Journal of the American College of Cardiology, ISSN 0735-1097, 2016, Volume 67, Issue 17, pp. 1994 - 2004
Abstract Background Platelet inhibitory effects induced by oral P2Y12 receptor antagonists are delayed in patients with ST-segment elevation myocardial... 
Cardiovascular | Internal Medicine | crushed tablet | pharmacodynamic | pharmacokinetic | platelets | CARDIAC & CARDIOVASCULAR SYSTEMS | TICAGRELOR | TRITON-TIMI 38 | BIOAVAILABILITY | CLOPIDOGREL | PLATELET INHIBITION | RAPID ACTIVITY | DOUBLE-BLIND | ANTIPLATELET ACTION | ELEVATION MYOCARDIAL-INFARCTION | ONSET | Transluminal angioplasty | Cardiology | Medical colleges
Journal Article
The New England journal of medicine, ISSN 1533-4406, 2013, Volume 369, Issue 14, pp. 1317 - 1326
Saxagliptin, a new oral antihyperglycemic drug in the DPP-4 inhibitor class, had no effect on the risk of cardiovascular events in patients with type 2... 
ALL-CAUSE | MEDICINE, GENERAL & INTERNAL | METAANALYSIS | EVENTS | GLUCOSE CONTROL | MICROALBUMINURIA | DISEASE | CLINICAL-USE | PREVENTION | RISK | DEATH | Dipeptidyl-Peptidase IV Inhibitors - adverse effects | Dipeptidyl-Peptidase IV Inhibitors - therapeutic use | Humans | Middle Aged | Hospitalization - statistics & numerical data | Male | Adamantane - therapeutic use | Aged, 80 and over | Cardiovascular Diseases - epidemiology | Cardiovascular Diseases - mortality | Female | Hypoglycemia - chemically induced | Heart Failure - epidemiology | Diabetes Mellitus, Type 2 - complications | Adamantane - adverse effects | Adamantane - analogs & derivatives | Hypoglycemic Agents - therapeutic use | Cardiovascular Diseases - etiology | Dipeptides - therapeutic use | Double-Blind Method | Pancreatitis - epidemiology | Dipeptides - adverse effects | Kaplan-Meier Estimate | Pancreatitis - chemically induced | Aged | Diabetes Mellitus, Type 2 - drug therapy | Hypoglycemic Agents - adverse effects | Type 2 diabetes | Complications and side effects | Patient outcomes | Dosage and administration | Drug therapy | Heart diseases | Risk factors | Saxagliptin | Myocardial infarction | Cerebral infarction | Heart attacks | Peptidase | Diabetes mellitus | Pancreatitis | Cardiovascular disease | Angina | Patients | Heart rate | Ischemia | Diabetes | Cardiovascular diseases | Diabetes mellitus (non-insulin dependent)
Journal Article
Journal Article
Indian Heart Journal, ISSN 0019-4832, 2016, Volume 68, Issue 4, pp. 539 - 551
Abstract Percutaneous coronary intervention (PCI) is effective in opening the infarct related artery and restoring thrombolysis in myocardial infarction flow 3... 
Cardiovascular | Thrombus aspiration | Primary percutaneous intervention | ST-elevation myocardial infarction | Coronary Circulation | Coronary Angiography | ST Elevation Myocardial Infarction - physiopathology | Humans | ST Elevation Myocardial Infarction - surgery | No-Reflow Phenomenon - etiology | No-Reflow Phenomenon - diagnosis | ST Elevation Myocardial Infarction - diagnosis | Percutaneous Coronary Intervention - adverse effects | curve | MBG, myocardial blush grade | OCT, optical coherence tomography | Review | MPV, mean platelet volume | TMPG, TIMI myocardial perfusion grade | CMRI, cardiac magnetic resonance imaging | TIMI, thrombolysis in myocardial infarction | ROC, receiver operating characteristics | MCE, myocardial contrast echocardiography | IS, infarct size | MACE, major adverse cardiovascular event | mural hemorrhage | PPCI, primary percutaneous coronary intervention | ICCU, intensive coronary care unit | IMH, intra myocardial | STR, ST-segment resolution | CFV, coronary flow velocity | IPC, ischemic pre-conditioning | PCI, percutaneous coronary intervention | PET, positron emission tomography | PLR, platelet lymphocyte ratio | LV, left ventricle | IVUS, intravascular ultrasound | CFR, coronary flow reserve | STEMI, ST-elevation myocardial infarction | IRA, infarct related artery | CTFC, corrected TIMI frame count | MVO, microvascular obstruction
Journal Article
Journal of the American College of Cardiology, ISSN 0735-1097, 06/2012, Volume 59, Issue 23, pp. 2091 - 2098
Journal Article