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Journal of Immunology, ISSN 0022-1767, 04/2019, Volume 202, Issue 8, pp. 2384 - 2396
MyD88 adaptor-like (Mal) protein is the most polymorphic of the four key adaptor proteins involved in TLR signaling. TLRs play a critical role in the... 
MAL/TIRAP REVEALS | TUBERCULOSIS | MACROPHAGES | ESCHERICHIA-COLI | SUSCEPTIBILITY | TOLL-LIKE RECEPTORS | LIPOPOLYSACCHARIDE | CONTAINING ADAPTER PROTEIN | IMMUNOLOGY | ASSEMBLY FORMATION | TIRAP
Journal Article
CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, ISSN 0392-856X, 05/2013, Volume 31, Issue 3, pp. S54 - S56
Objective. The single nucleotide polymorphism (SNP) of TIRAP (Serine 180 leucine, S180L) that is shown to be associated with Behcet's disease (BD) in a... 
MAL/TIRAP | Behcet's disease | RHEUMATOLOGY | genetic susceptibility | ASSOCIATION | TIRAP
Journal Article
Microbes and Infection, ISSN 1286-4579, 03/2016, Volume 18, Issue 3, pp. 180 - 189
(Kp) a common cause of pneumonia leads to intense lung injury and mortality that are correlated with infective exacerbations. Probiotics are a class of... 
Probiotic | Microbiota | Inflammation | Bifidobacterium longum 51A | Mal/TIRAP | Klebsiella pneumoniae | Bifidobacterium longum 5
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 08/2017, Volume 114, Issue 32, pp. E6480 - E6489
Journal Article
JOURNAL OF THORACIC DISEASE, ISSN 2072-1439, 02/2019, Volume 11, Issue 2, pp. 583 - 594
Background: Toll-like receptor 1 (TLR1) and TLR6 play important roles in the innate immune response against Mycobacterium tuberculosis (M.TB) via interactions... 
LIPOPEPTIDE | IMMUNE-RESPONSE | Toll-like receptor 1 (TLR1) | TIR domain-containing adaptor protein (TIRAP) | CHINESE | PREVALENCE | CHILDHOOD | TIRAP | Myeloid differentiation factor 88 | POLYMORPHISMS | RESPIRATORY SYSTEM | Toll-like receptor 6 (TLR6) | RESISTANCE | tuberculosis (TB) | Original
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 07/2003, Volume 278, Issue 28, pp. 26258 - 26264
In this study we have identified members of the Toll-like receptor (TLR) family (namely, TLRs 4, 6, 8, and 9) as proteins to which the intracellular protein... 
SIGNAL-TRANSDUCTION | X-CHROMOSOME | PATHWAY | BIOCHEMISTRY & MOLECULAR BIOLOGY | ALPHA | CELL RECEPTOR | SRC FAMILY KINASES | ADAPTER MOLECULE | IMMUNODEFICIENCY | TIRAP | SH3 DOMAIN
Journal Article
Journal Article
Nature Genetics, ISSN 1061-4036, 04/2007, Volume 39, Issue 4, pp. 523 - 528
Journal Article
by Nguyen, TTN and Seo, E and Choi, J and Le, OTT and Kim, JY and Jou, I and Lee, SY
CELLULAR SIGNALLING, ISSN 0898-6568, 10/2017, Volume 38, pp. 159 - 170
Phosphatidylinositol 4,5-bisphosphate (PIP2) is an important lipid regulator of membrane signaling and remodeling processes. Accumulating evidence indicates a... 
ACTIVATION | PHAGOCYTOSIS | Immune response | INFLAMMATORY RESPONSES | PIP5K alpha | ALPHA | AUTOPHAGY | PLASMA-MEMBRANE | TIRAP | PHOSPHOINOSITIDES | Microglia | CELL BIOLOGY | STREPTOCOCCUS-PNEUMONIAE | ACTIN CYTOSKELETON | PIP2 | BRAIN | TLR2 | Phosphates | Nitric oxide | Immunotherapy | Physiological aspects | Fluorescence | Phospholipids | Muscle proteins | Macrophages | Mitogens | Protein kinases | Organic acids
Journal Article
International Journal of Molecular Medicine, ISSN 1107-3756, 06/2011, Volume 27, Issue 6, pp. 795 - 801
Toll-like receptors (TLRs) are important pathogen-associated molecular pattern recognition receptors involved in initiating immune responses. The adaptor... 
Innate immunity | Mal/TIRAP | Atopic dermatitis | Toll-like receptor | Polymorphism | MEDICINE, RESEARCH & EXPERIMENTAL | DOMAIN | PROTEIN | DENDRITIC CELLS | TUBERCULOSIS | SUSCEPTIBILITY | atopic dermatitis | polymorphism | TIRAP | innate immunity | PYOGENIC BACTERIAL-INFECTIONS | TOLL | TLR4
Journal Article
Malaria Journal, ISSN 1475-2875, 2012, Volume 11, Issue 1, pp. 196 - 196
Journal Article
Current Pediatric Research, ISSN 0971-9032, 10/2014, Volume 18, Issue 2, pp. 63 - 68
Journal Article
Infection, Genetics and Evolution, ISSN 1567-1348, 03/2019, Volume 68, pp. 84 - 90
Toll-like receptors (TLRs) play a critical role in initiating an immune response to infections. In this study, we examined whether single nucleotide... 
Toll-like receptors | Association study | Host genetics | Single nucleotide polymorphisms | Susceptibility | Pulmonary tuberculosis | INFECTIOUS DISEASES | RECOGNITION | VARIANTS | TIRAP | POLYMORPHISMS | RESISTANCE | CD14 | RECEPTORS | ASSOCIATION | MYD88 | Medical research | Genes | Genetic research | Medicine, Experimental | Genetic aspects
Journal Article
MICROBES AND INFECTION, ISSN 1286-4579, 03/2016, Volume 18, Issue 3, pp. 180 - 189
Klebsiella pneumoniae (Kp) a common cause of pneumonia leads to intense lung injury and mortality that are correlated with infective exacerbations. Probiotics... 
Probiotic | INFECTIOUS DISEASES | MICROBIOLOGY | Inflammation | Mal/TIRAP | GUT MICROBIOTA | IMMUNOLOGY | RECEPTOR GPR43 | MURINE MODEL | Microbiota | INFLUENZA-VIRUS INFECTION | IMMUNE-RESPONSES | HOST-DEFENSE |