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Brain, ISSN 0006-8950, 2012, Volume 135, Issue 11, pp. 3251 - 3264
.... Tissue plasminogen activator is a serine protease that converts plasminogen to plasmin, a protease that dissolves blood clots... 
traumatic brain injury | matrix metalloproteinase-3 | plasminogen activator inhibitor-1 | tissue plasminogen activator | neurovascular unit | MULTIPLE-SCLEROSIS LESIONS | RECEPTOR-RELATED PROTEIN | TPA | FOCAL CEREBRAL-ISCHEMIA | BARRIER BREAKDOWN | NEUROSCIENCES | CLINICAL NEUROLOGY | STROKE | MATRIX METALLOPROTEINASES | CENTRAL-NERVOUS-SYSTEM | EXPRESSION | BLOOD | Capillary Permeability - physiology | Tissue Plasminogen Activator - metabolism | Brain Injuries - drug therapy | Humans | Middle Aged | Injections, Intraventricular | Capillary Permeability - drug effects | Male | Brain Injuries - metabolism | Brain Injuries - physiopathology | Plasminogen Activator Inhibitor 1 - physiology | Matrix Metalloproteinase Inhibitors - therapeutic use | Brain - metabolism | Dose-Response Relationship, Drug | Brain - blood supply | Tissue Plasminogen Activator - antagonists & inhibitors | Plasminogen Activator Inhibitor 1 - metabolism | Aged, 80 and over | Recovery of Function - physiology | Adult | Disease Models, Animal | Albumins - metabolism | Mice, Inbred C57BL | Plasminogen Activator Inhibitor 1 - administration & dosage | Tissue Plasminogen Activator - administration & dosage | Tissue Plasminogen Activator - physiology | Animals | Brain Injuries - cerebrospinal fluid | Aged | Mice | Matrix Metalloproteinases - metabolism | Stroke | Central nervous system | Membrane permeability | Albumin | Homeostasis | Cerebrospinal fluid | Matrix metalloproteinase | Permeability | Trauma | Plasmin | t-Plasminogen activator | lipoprotein receptors | neuroserpin | plasminogen | Proteolysis | Plasma membranes | Chromium | Serine proteinase | Brain injury | Original
Journal Article
The Lancet (British edition), ISSN 0140-6736, 2012, Volume 379, Issue 9834, pp. 2352 - 2363
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