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toll-like receptors (306) 306
tlr1 protein (300) 300
science & technology (261) 261
tlr2 protein (163) 163
life sciences & biomedicine (162) 162
immune system (158) 158
humans (142) 142
proteins (139) 139
immunology (129) 129
inflammation (122) 122
cytokines (115) 115
immune response (115) 115
tlr4 protein (103) 103
gene expression (101) 101
receptors (100) 100
multidisciplinary sciences (97) 97
science & technology - other topics (97) 97
medicine (91) 91
research article (91) 91
science (90) 90
animals (84) 84
signal transduction (80) 80
female (70) 70
innate immunity (68) 68
genes (66) 66
male (61) 61
tlr3 protein (61) 61
infections (60) 60
immunity (57) 57
ligands (55) 55
genetic aspects (52) 52
infectious diseases (51) 51
tlr5 protein (49) 49
analysis (48) 48
interleukin 6 (48) 48
tlr9 protein (48) 48
tlr7 protein (45) 45
pattern recognition (44) 44
health aspects (43) 43
mice (43) 43
toll-like receptors - genetics (43) 43
adult (42) 42
pathogens (42) 42
single-nucleotide polymorphism (42) 42
macrophages (41) 41
bacteria (40) 40
lipopolysaccharides (40) 40
research (40) 40
toll-like receptor 1 - genetics (39) 39
cell biology (38) 38
middle aged (38) 38
toll-like receptor 2 - metabolism (38) 38
leukocytes (37) 37
signaling (37) 37
polymerase chain reaction (36) 36
toll-like receptors - metabolism (35) 35
infection (34) 34
lymphocytes t (34) 34
studies (34) 34
kinases (33) 33
microbiology (32) 32
pathogenesis (32) 32
polymorphism, single nucleotide (32) 32
biology (31) 31
flow cytometry (31) 31
interleukin 8 (31) 31
monocytes (31) 31
myd88 protein (31) 31
biochemistry (30) 30
tumor necrosis factor-α (30) 30
deoxyribonucleic acid--dna (29) 29
genetics (29) 29
biology and life sciences (28) 28
cells, cultured (28) 28
tlr1 (28) 28
cancer (27) 27
medical research (27) 27
nf-κb protein (27) 27
toll-like receptor 1 - metabolism (27) 27
antigens (26) 26
medicine and health sciences (26) 26
patients (26) 26
polymorphism (26) 26
tuberculosis (26) 26
bacterial infections (25) 25
toll-like receptor (25) 25
interferon (24) 24
interleukin 1 (24) 24
microorganisms (24) 24
toll-like receptor 2 - genetics (24) 24
aged (23) 23
genetic predisposition to disease (23) 23
genomes (23) 23
immunomodulation (23) 23
risk factors (23) 23
rna (23) 23
dendritic cells (22) 22
tumor necrosis factor-tnf (22) 22
cell activation (21) 21
interleukin 10 (21) 21
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1. Full Text Phagocytosis-mediated M1 activation by chitin but not by chitosan
by Davis, Spring and Cirone, Aiko M and Menzie, Janet and Russell, Floyd and Dorey, C. Kathleen and Shibata, Yoshimi and Wei, Jianning and Nan, Changlong
American Journal of Physiology: Cell Physiology, ISSN 0363-6143, 07/2018, Volume 315, Issue 1, pp. C62 - C72
Lyn | mTOR | LAMTOR1 | MyD88 | TLR2 | Physiology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Phagocytosis - drug effects | Membrane Glycoproteins - metabolism | Protein-Tyrosine Kinases - metabolism | Mice, Inbred C57BL | Male | Toll-Like Receptor 2 - metabolism | Chitin - pharmacology | Macrophages - metabolism | Animals | Cell Differentiation - drug effects | Chitosan - pharmacology | Macrophages - drug effects | Mice | Phosphorylation - drug effects | Adaptor Proteins, Signal Transducing - metabolism | Macrophage Activation - drug effects | Myeloid Differentiation Factor 88 - metabolism | Chitinase | TOR protein | Allergens | Genes | Interleukin 1 receptors | Macrophages | CD14 antigen | Tissues | Microparticles | Proteins | Cell growth | Cell activation | Actin | Interleukin 1 | Toll-like receptors | Protein-tyrosine kinase | Adaptor proteins | Tyrosine | Pathogens | MAP kinase | Chitin | Rapamycin | TLR1 protein | TLR2 protein | Lck protein | MyD88 protein | Lyn protein | Chitosan | Phagocytosis | Index Medicus
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2. Full Text Toll-like receptor 2: An important immunomodulatory molecule during Helicobacter pylori infection
by Nemati, Maryam and Larussa, Tiziana and Khorramdelazad, Hossein and Mahmoodi, Merat and Jafarzadeh, Abdollah
Life sciences (1973), ISSN 0024-3205, 06/2017, Volume 178, pp. 17 - 29
H. pylori | Pathogen recognition receptor | TLR2 | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Helicobacter pylori - immunology | Immunity, Innate - immunology | Animals | Humans | Toll-Like Receptors - immunology | NF-kappa B - immunology | Toll-Like Receptor 2 - immunology | Helicobacter Infections - immunology | Adaptive Immunity - immunology | Cytokines - immunology | Helicobacter Infections - microbiology | Heat shock proteins | Helicobacter infections | B cells | Helicobacter pylori | Dendritic cells | Health aspects | COX-2 inhibitors | Biological response modifiers | Interferon | Single nucleotide polymorphisms | Mitogens | Protein kinases | Protein binding | Hsp60 protein | Epithelial cells | Infections | Macrophages | Lipopolysaccharides | Proteins | Receptors | Cell activation | Microorganisms | Toll-like receptors | Bacteria | Immune system | Bacterial infections | Immune response | TLR5 protein | Immunoregulation | Immunomodulation | Leukocytes (neutrophilic) | TLR4 protein | TLR9 protein | Monocytes | TLR1 protein | Lymphocytes B | TLR2 protein | Index Medicus
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3. Full Text Effects of aging and lifelong aerobic exercise on expression of innate immune components in human skeletal muscle
by Perkins, Ryan K and Lavin, Kaleen M and Raue, Ulrika and Jemiolo, Bozena and Trappe, Scott W and Trappe, Todd A
Journal of applied physiology (1985), ISSN 8750-7587, 12/2020, Volume 129, Issue 6, pp. 1483 - 1492
Adaptor proteins | NF-κB protein | TLR7 protein | Muscles | TLR4 protein | Adaptors | Gene expression | Aerobics | TLR3 protein | Skeletal muscle | Musculoskeletal system | Physical fitness | Exercise | TLR1 protein | Quadriceps muscle | Toll-like receptors | Aging | MyD88 protein | Immune system | Index Medicus
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4. Full Text Human Keratinocytes Express Functional Toll-Like Receptor 3, 4, 5, and 9
by Lebre, Maria C and van der Aar, Angelic M.G and van Baarsen, Lisa and van Capel, Toni M.M and Schuitemaker, Joost H.N and Kapsenberg, Martien L and de Jong, Esther C
Journal of investigative dermatology, ISSN 0022-202X, 02/2007, Volume 127, Issue 2, pp. 331 - 341
Life Sciences & Biomedicine | Dermatology | Science & Technology | Oligonucleotides - genetics | Phosphorylation | Toll-Like Receptor 5 - genetics | Humans | Toll-Like Receptor 9 - genetics | I-kappa B Proteins - metabolism | RNA, Messenger - metabolism | Flagellin - pharmacology | Tissue Distribution | Cell Nucleus - metabolism | Protein Isoforms - metabolism | Biological Transport | Oligonucleotides - pharmacology | Toll-Like Receptor 3 - genetics | Toll-Like Receptors - metabolism | Chemokine CXCL9 | Toll-Like Receptor 5 - metabolism | Poly I-C - pharmacology | Cytokines - metabolism | Cells, Cultured | Toll-Like Receptor 4 - genetics | Toll-Like Receptor 3 - metabolism | Toll-Like Receptor 4 - metabolism | Chemokine CXCL10 | Transcription Factor RelA - metabolism | Keratinocytes - metabolism | Toll-Like Receptors - genetics | Chemokines, CXC - metabolism | Lipopolysaccharides - pharmacology | CpG Islands | Ligands | Chemokines - metabolism | Toll-Like Receptor 9 - metabolism | CD40 antigen | Oligonucleotides | Flagellin | mRNA | intercellular adhesion molecule 1 | Immunity | Lipopolysaccharides | CXC chemokines | CCL20 protein | Toll-like receptors | CpG islands | TLR7 protein | Keratinocytes | Nuclear transport | Stress | TLR3 protein | TLR9 protein | TLR1 protein | External stimuli | CXCL10 protein | Histocompatibility antigen HLA | Interferon | Internet | Monocyte chemoattractant protein 1 | Tumor necrosis factor- alpha | Index Medicus
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5. Full Text Quantitative Expression of Toll-Like Receptor 1-10 mRNA in Cellular Subsets of Human Peripheral Blood Mononuclear Cells and Sensitivity to CpG Oligodeoxynucleotides
by Hornung, Veit and Rothenfusser, Simon and Britsch, Stefanie and Krug, Anne and Jahrsdorfer, Bernd and Giese, Thomas and Endres, Stefan and Hartmann, Gunther
The Journal of immunology (1950), ISSN 0022-1767, 05/2002, Volume 168, Issue 9, pp. 4531 - 4537
Life Sciences & Biomedicine | Immunology | Science & Technology | Toll-Like Receptor 1 | Toll-Like Receptor 2 | Adjuvants, Immunologic - pharmacology | Dendritic Cells - immunology | Humans | Membrane Glycoproteins - biosynthesis | Blood - immunology | Toll-Like Receptor 9 | Monocytes - immunology | Toll-Like Receptor 7 | RNA, Messenger - biosynthesis | Toll-Like Receptors | T-Lymphocytes - drug effects | Leukocytes, Mononuclear - immunology | Polymerase Chain Reaction | Killer Cells, Natural - immunology | Dendritic Cells - drug effects | Clone Cells | Receptors, Cell Surface - biosynthesis | Leukocytes, Mononuclear - classification | Drosophila Proteins | Leukocytes, Mononuclear - drug effects | Cells, Cultured | Gene Expression Regulation | DNA-Binding Proteins - genetics | Membrane Glycoproteins - genetics | Monocytes - drug effects | B-Lymphocytes - drug effects | B-Lymphocytes - immunology | Protein Isoforms - biosynthesis | Immunologic Memory | T-Lymphocytes - immunology | Killer Cells, Natural - drug effects | Kinetics | Oligodeoxyribonucleotides - pharmacology | Toll-Like Receptor 10 | DNA-Binding Proteins - biosynthesis | Protein Isoforms - genetics | Receptors, Cell Surface - genetics | TLR6 protein | Toll-like receptors | TLR1 protein | oligodeoxynucleotides | TLR7 protein | TLR9 protein | Index Medicus | Abridged Index Medicus
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6. Full Text Toll‐like receptor polymorphism in host immune response to infectious diseases: A review
by Mukherjee, Suprabhat and Huda, Sahel and Sinha Babu, Santi P
Scandinavian journal of immunology, ISSN 0300-9475, 07/2019, Volume 90, Issue 1, pp. e12771 - n/a
polymorphism | pathogen‐associated molecular pattern | susceptibility | infectious disease | toll‐like receptor | resistance | toll-like receptor | pathogen-associated molecular pattern | Life Sciences & Biomedicine | Immunology | Science & Technology | Immunologic Surveillance | Genetic Predisposition to Disease | Animals | Humans | Toll-Like Receptors - genetics | Pathogen-Associated Molecular Pattern Molecules - immunology | Communicable Diseases - genetics | Structure-Activity Relationship | Immunity - genetics | Polymorphism, Genetic | Drug resistance in microorganisms | Medical research | Immune response | Parasitic diseases | Medicine, Experimental | Genetic aspects | Disease susceptibility | Single nucleotide polymorphisms | Epidemiology | Residues | Population studies | Infections | Single-nucleotide polymorphism | Nucleotides | Immunity | Tropical diseases | Proteins | Signal transduction | Receptors | Toll-like receptors | Genetic factors | Immune system | Vector-borne diseases | TLR7 protein | Malaria | TLR5 protein | Amino acid sequence | Immunosurveillance | Inflammation | Leishmaniasis | TLR4 protein | TLR3 protein | TLR9 protein | Infectious diseases | Tuberculosis | TLR1 protein | Filariasis | TLR2 protein | Polymorphism | Structure-function relationships | Index Medicus
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7. Full Text Antileishmanial drugs activate inflammatory signaling pathways via toll-like receptors (docking approach) from Leishmania amazonensis-infected macrophages
by Valentim-Silva, João Rafael and Macedo, Sharon Rose Aragão and de Barros, Neuza Biguinati and dos Santos Ferreira, Amália and da Silva, João Hermínio Martins and de Figueiredo Nicolete, Larissa Deadame and Nicolete, Roberto
International immunopharmacology, ISSN 1567-5769, 08/2020, Volume 85, pp. 106640 - 106640
Inflammation | Leishmaniasis | Antileishmanial drugs | TLRs | Molecular docking | Pharmacology & Pharmacy | Immunology | Life Sciences & Biomedicine | Science & Technology | Drugs | Transcription factors | Transcription | Kinases | Macrophages | Antiinfectives and antibacterials | Proteins | Signal transduction | Receptors | Cell activation | Microbicides | Pathways | Toll-like receptors | Vector-borne diseases | NF-κB protein | Stat3 protein | MAP kinase | Pentamidine | TLR4 protein | Binders | TLR3 protein | Signaling | TLR1 protein | Amphotericin B | TLR2 protein | Signal processing | Affinity | Index Medicus
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8. Full Text Lung CD8+ T cells in COPD have increased expression of bacterial TLRs
by Freeman, Christine M and Martinez, Fernando J and Han, MeiLan K and Washko, George R and McCubbrey, Alexandra L and Chensue, Stephen W and Arenberg, Douglas A and Meldrum, Catherine A and McCloskey, Lisa and Curtis, Jeffrey L
Respiratory research, ISSN 1465-9921, 02/2013, Volume 14, Issue 1, pp. 13 - 13
Toll-like receptors | CD8+ T cells | Chronic obstructive pulmonary disease | Lung | Life Sciences & Biomedicine | Respiratory System | Science & Technology | Lung - microbiology | CD8-Positive T-Lymphocytes - microbiology | Prospective Studies | Pulmonary Disease, Chronic Obstructive - microbiology | Humans | Middle Aged | Cells, Cultured | Male | Lung - cytology | Toll-Like Receptors - biosynthesis | CD8-Positive T-Lymphocytes - metabolism | Female | Aged | Lung - metabolism | Pulmonary Disease, Chronic Obstructive - metabolism | Gene Expression Regulation, Bacterial | Killer cells | Lung diseases, Obstructive | Smokers | T cells | Cells | Pathology | T cell receptors | Immunology | Cytokines | Immune system | Index Medicus | Cell culture | granzyme B | TLR5 protein | CD8 antigen | CCL3 protein | Data processing | Interleukin 13 | Lymphocytes T | TLR4 protein | TLR3 protein | TLR9 protein | CD4 antigen | FasL protein | TLR1 protein | endopeptidase | TLR2 protein | Serine proteinase | Natural killer cells | CD56 antigen | Perforin | Monocyte chemoattractant protein 1 | Research
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