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The Journal of experimental medicine, ISSN 1540-9538, 2010, Volume 207, Issue 2, pp. 391 - 404
Journal Article
Cell Death and Differentiation, ISSN 1350-9047, 03/2017, Volume 24, Issue 3, pp. 500 - 510
Journal Article
The Journal of Immunology, ISSN 0022-1767, 10/2009, Volume 183, Issue 7, pp. 4560 - 4568
Journal Article
Cell Death and Disease, ISSN 2041-4889, 02/2013, Volume 4, Issue 2, pp. e499 - e499
EVER1 and 2 confer resistance to cutaneous oncogenic human papillomavirus infections by downregulating the activating protein 1 (AP-1) signaling pathway.... 
EVER2 | TRADD | Apoptosis | Polymorphism | apoptosis | polymorphism | CELL BIOLOGY | Receptor-Interacting Protein Serine-Threonine Kinases - metabolism | Tumor Necrosis Factor-alpha - metabolism | Fas Ligand Protein - metabolism | Apoptosis - drug effects | Humans | Tumor Necrosis Factor-alpha - genetics | Caspase 8 - metabolism | MicroRNAs - metabolism | NF-kappa B - metabolism | Recombinant Proteins - biosynthesis | TNF Receptor-Associated Death Domain Protein - genetics | Fas Ligand Protein - pharmacology | TNF-Related Apoptosis-Inducing Ligand - pharmacology | RNA Interference | HEK293 Cells | Inhibitor of Apoptosis Proteins - metabolism | Membrane Proteins - metabolism | TNF Receptor-Associated Death Domain Protein - metabolism | Protein Structure, Tertiary | Jurkat Cells | Membrane Proteins - genetics | TNF Receptor-Associated Factor 2 - metabolism | Recombinant Proteins - genetics | Recombinant Proteins - pharmacology | TNF-Related Apoptosis-Inducing Ligand - metabolism | Tumor Necrosis Factor-alpha - pharmacology | TNF Receptor-Associated Death Domain Protein - chemistry | Membrane Proteins - antagonists & inhibitors | Alleles | Protein Binding | Fas Ligand Protein - genetics | TNF-Related Apoptosis-Inducing Ligand - genetics | Caspase 8 | Inhibitor of Apoptosis Proteins | Receptor-Interacting Protein Serine-Threonine Kinases | Recombinant Proteins | Tumor Necrosis Factor-alpha | TNF Receptor-Associated Factor 2 | Fas Ligand Protein | Membrane Proteins | Life Sciences | TNF-Related Apoptosis-Inducing Ligand | NF-kappa B | Immunology | MicroRNAs | TNF Receptor-Associated Death Domain Protein | Original
Journal Article
The Journal of biological chemistry, ISSN 1083-351X, 2012, Volume 287, Issue 42, pp. 34979 - 34991
Journal Article
Protein Science, ISSN 0961-8368, 07/2016, Volume 25, Issue 7, pp. 1273 - 1289
Tumor necrosis factor receptor‐associated factors (TRAFs) constitute a family of adapter proteins that act in numerous signaling pathways important in human... 
protein–protein interactions | interaction specificity | deep mutational scanning | bacterial surface display | Deep mutational scanning | Interaction specificity | Protein-protein interactions | Bacterial surface display | RECEPTOR-ASSOCIATED FACTORS | SITE | DOMAIN | SPECIFICITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | IDENTIFICATION | protein-protein interactions | CD40 RECOGNITION | FAMILY | STRUCTURAL BASIS | PROTEIN FUNCTION | EPSTEIN-BARR-VIRUS | Protein Structure, Secondary | Humans | TNF Receptor-Associated Factor 2 - genetics | Models, Molecular | TNF Receptor-Associated Factor 2 - metabolism | TNF Receptor-Associated Factor 3 - metabolism | TNF Receptor-Associated Factor 3 - chemistry | TNF Receptor-Associated Factor 5 - metabolism | DNA Mutational Analysis - methods | Tumor Necrosis Factor Receptor-Associated Peptides and Proteins - metabolism | Tumor Necrosis Factor Receptor-Associated Peptides and Proteins - chemistry | TNF Receptor-Associated Factor 5 - genetics | CD40 Antigens - metabolism | Peptides - metabolism | TNF Receptor-Associated Factor 5 - chemistry | TNF Receptor-Associated Factor 3 - genetics | TNF Receptor-Associated Factor 2 - chemistry | Protein Binding | Adaptor Proteins, Signal Transducing - metabolism | Binding Sites | Tumor Necrosis Factor Receptor-Associated Peptides and Proteins - genetics | Proteins | Comparative analysis | Escherichia coli | Protein binding | Libraries | Peptides | Adapter proteins | Binding sites
Journal Article
Arteriosclerosis, thrombosis, and vascular biology, ISSN 1524-4636, 2007, Volume 27, Issue 5, pp. 1101 - 1107
OBJECTIVE—Several lines of evidence implicate CD40 ligand (CD40L, CD154) as a mediator and marker of atherosclerosis. This study investigated the involvement... 
CD40L | Signaling | Inflammation | TRAF | Atherosclerosis | atherosclerosis | ACTIVATION | signaling | MACROPHAGES | RECEPTOR | VASCULAR SMOOTH-MUSCLE | TISSUE FACTOR EXPRESSION | TARGETED DISRUPTION | inflammation | PERIPHERAL VASCULAR DISEASE | MICE | LIGAND | HEMATOLOGY | NF-KAPPA-B | UP-REGULATION | Inflammation - pathology | RNA, Small Interfering - genetics | Humans | TNF Receptor-Associated Factor 2 - genetics | CD40 Ligand - immunology | Saphenous Vein - metabolism | Atherosclerosis - etiology | Inflammation - metabolism | TNF Receptor-Associated Factor 3 - genetics | Polymerase Chain Reaction | TNF Receptor-Associated Factor 6 - genetics | Endothelium, Vascular - immunology | Atherosclerosis - pathology | Gene Expression | Endothelial Cells - metabolism | TNF Receptor-Associated Factor 1 - metabolism | TNF Receptor-Associated Factor 1 - genetics | TNF Receptor-Associated Factor 2 - metabolism | Saphenous Vein - pathology | TNF Receptor-Associated Factor 3 - metabolism | TNF Receptor-Associated Factor 5 - metabolism | Atherosclerosis - metabolism | Blotting, Western | Disease Progression | Endothelial Cells - immunology | TNF Receptor-Associated Factor 5 - genetics | Animals | Endothelium, Vascular - metabolism | TNF Receptor-Associated Factor 6 - metabolism | Endothelium, Vascular - pathology | Mice | Endothelial Cells - pathology | Saphenous Vein - drug effects
Journal Article
Cancer cell, ISSN 1535-6108, 2014, Volume 26, Issue 2, pp. 177 - 189
Journal Article
Journal Article
Current Opinion in Hematology, ISSN 1065-6251, 01/2008, Volume 15, Issue 1, pp. 42 - 48
PURPOSE OF REVIEWThis review will focus on the emerging role of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)/TRAIL-receptors in the... 
TRAIL receptors | TRAIL | Hematopoiesis | Hematological malignancies | hematological malignancies | SELECTIVE-INHIBITION | hematopoiesis | IN-VITRO | PATHWAY | ENDOTHELIAL-CELLS | MYELOMA CELLS | LEUKEMIA-CELLS | RESISTANCE | TRAIL-INDUCED APOPTOSIS | RECEPTORS | HEMATOLOGY | EXPRESSION | Hematologic Neoplasms - therapy | Recombinant Proteins - therapeutic use | Receptors, Tumor Necrosis Factor - agonists | Receptors, TNF-Related Apoptosis-Inducing Ligand - agonists | Humans | Bone Marrow - physiology | Receptors, TNF-Related Apoptosis-Inducing Ligand - immunology | Receptors, Tumor Necrosis Factor - physiology | TNF-Related Apoptosis-Inducing Ligand - antagonists & inhibitors | TNF-Related Apoptosis-Inducing Ligand - pharmacology | TNF-Related Apoptosis-Inducing Ligand - agonists | TNF-Related Apoptosis-Inducing Ligand - deficiency | Hematopoiesis - physiology | Hematopoietic Stem Cells - drug effects | Osteoprotegerin - physiology | Combined Modality Therapy | TNF-Related Apoptosis-Inducing Ligand - therapeutic use | Mice, Knockout | Animals | Hematologic Diseases - physiopathology | TNF-Related Apoptosis-Inducing Ligand - physiology | Recombinant Proteins - immunology | Receptors, TNF-Related Apoptosis-Inducing Ligand - physiology | Mice | Apoptosis - physiology | Receptors, Tumor Necrosis Factor - immunology | TNF-Related Apoptosis-Inducing Ligand - genetics
Journal Article
Immunology, ISSN 0019-2805, 01/2015, Volume 144, Issue 1, pp. 21 - 33
Summary Inhibition of the CD40–CD154 pathway controls inflammatory disorders. Unfortunately, administration of anti‐CD154 monoclonal antibodies causes... 
muscle smooth cell | monocyte | epithelial cell | inflammation | endothelial cell | Epithelial cell | Endothelial cell | Muscle smooth cell | Inflammation | Monocyte | ALLOGRAFT-REJECTION | INTERCELLULAR-ADHESION MOLECULE-1 | TRAF BINDING-SITES | LOW-DENSITY-LIPOPROTEIN | CD40 LIGAND | IMMUNOLOGY | ENDOTHELIAL-CELLS | SMOOTH-MUSCLE-CELLS | RECEPTOR-ASSOCIATED FACTOR-2 | ANTIMICROBIAL ACTIVITY | T-CELLS | CD40 Antigens - antagonists & inhibitors | Chemokine CCL2 - immunology | Dendritic Cells - immunology | Humans | TNF Receptor-Associated Factor 2 - genetics | Myocytes, Smooth Muscle - pathology | Dendritic Cells - pathology | TNF Receptor-Associated Factor 6 - antagonists & inhibitors | TNF Receptor-Associated Factor 6 - immunology | CD40 Ligand - immunology | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Signal Transduction - immunology | Inflammation - drug therapy | TNF Receptor-Associated Factor 3 - genetics | CD40 Antigens - genetics | TNF Receptor-Associated Factor 6 - genetics | Thromboplastin - immunology | Cell Line | TNF Receptor-Associated Factor 3 - antagonists & inhibitors | Intercellular Adhesion Molecule-1 - immunology | Mesangial Cells - immunology | Chemokine CCL2 - genetics | Up-Regulation - genetics | Inflammation - immunology | Signal Transduction - genetics | Peptides - pharmacology | Endothelial Cells - immunology | Up-Regulation - drug effects | TNF Receptor-Associated Factor 2 - antagonists & inhibitors | Animals | CD40 Ligand - genetics | Signal Transduction - drug effects | TNF Receptor-Associated Factor 2 - immunology | Up-Regulation - immunology | Intercellular Adhesion Molecule-1 - genetics | TNF Receptor-Associated Factor 3 - immunology | Thromboplastin - genetics | Mesangial Cells - pathology | Inflammation - genetics | Myocytes, Smooth Muscle - immunology | Mice | Peroxidases - genetics | Peroxidases - immunology | Endothelial Cells - pathology | CD40 Antigens - immunology | Leucocytes | Smooth muscle | Mutation | Inflammatory diseases | Cell adhesion & migration | Immune system | Recruitment | Original
Journal Article