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Immunological Reviews, ISSN 0105-2896, 11/2011, Volume 244, Issue 1, pp. 55 - 74
A large and diverse group of receptors utilizes the family of cytoplasmic signaling proteins known as tumor necrosis factor receptor (TNFR)‐associated factors... 
tumor necrosis factor receptor | lymphocyte activation | signal transduction | tumor necrosis factor receptor associated factor | Signal transduction | Lymphocyte activation | Tumor necrosis factor receptor associated factor | Tumor necrosis factor receptor | CPG OLIGODEOXYNUCLEOTIDES | ACTIVATED PROTEIN-KINASE | HUMAN CD40 RECEPTOR | IMMUNOLOGY | TERMINAL KINASE | LYMPHOTOXIN-BETA-RECEPTOR | TOLL-LIKE RECEPTORS | LATENT MEMBRANE-PROTEIN | FAMILY-MEMBER TALL-1 | NF-KAPPA-B | T-CELLS | Tumor Necrosis Factor-alpha - metabolism | Humans | Protein Processing, Post-Translational - genetics | Tumor Necrosis Factor-alpha - genetics | NF-kappa B - immunology | Ubiquitin - metabolism | Cell Survival - genetics | TNF Receptor-Associated Factor 5 - immunology | NF-kappa B - metabolism | Signal Transduction - immunology | T-Lymphocytes - metabolism | Myeloid Cells - immunology | TNF Receptor-Associated Factor 3 - genetics | Gene Expression - immunology | Tumor Necrosis Factor-alpha - immunology | Protein Processing, Post-Translational - immunology | B-Lymphocytes - metabolism | Receptors, Tumor Necrosis Factor - genetics | Receptors, Tumor Necrosis Factor - metabolism | TNF Receptor-Associated Factor 3 - metabolism | Signal Transduction - genetics | Ubiquitin - genetics | TNF Receptor-Associated Factor 5 - metabolism | Cell Survival - immunology | Immunity, Innate | Mice, Knockout | TNF Receptor-Associated Factor 5 - genetics | Animals | B-Lymphocytes - immunology | NF-kappa B - genetics | TNF Receptor-Associated Factor 3 - immunology | Myeloid Cells - metabolism | Protein Binding | T-Lymphocytes - immunology | Mice | Receptors, Tumor Necrosis Factor - immunology | Ubiquitin - immunology | Ubiquitin | T cells | Tumor necrosis factor | Necrosis | Tumors
Journal Article
Immunity, ISSN 1074-7613, 05/2012, Volume 36, Issue 5, pp. 742 - 754
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 06/2017, Volume 292, Issue 24, pp. 10169 - 10179
Cytokines, including receptor activator of nuclear factor kappa B ligand (RANKL) and TNF, induce increased osteoclast (OC) formation and bone loss in... 
RHEUMATOID-ARTHRITIS | TUMOR-NECROSIS-FACTOR | GROWTH-FACTOR-BETA | ACTIVATION | TGF-BETA | C-FOS | BIOCHEMISTRY & MOLECULAR BIOLOGY | DEFECTIVE INTERLEUKIN-1 | NF-KAPPA-B | T-CELLS | BONE-RESORPTION | Tumor Necrosis Factor-alpha - metabolism | Bone and Bones - pathology | RANK Ligand - metabolism | Spleen - immunology | Tumor Necrosis Factor-alpha - genetics | Autophagy - drug effects | Tumor Necrosis Factor-alpha - agonists | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Bone and Bones - drug effects | Chloroquine - pharmacology | Proteolysis - drug effects | Osteoclasts - immunology | TNF Receptor-Associated Factor 3 - genetics | Bone and Bones - metabolism | Cell Culture Techniques | TNF Receptor-Associated Factor 6 - genetics | Bone Demineralization, Pathologic - metabolism | Osteoclasts - pathology | Actin Cytoskeleton - metabolism | Osteogenesis - drug effects | Cells, Cultured | TNF Receptor-Associated Factor 3 - metabolism | Spleen - cytology | Actin Cytoskeleton - immunology | Osteoclasts - metabolism | Mice, Knockout | RANK Ligand - genetics | Animals | Spleen - metabolism | Protein Stability - drug effects | TNF Receptor-Associated Factor 6 - metabolism | Bone Demineralization, Pathologic - pathology | Mice | Actin Cytoskeleton - pathology | Bone and Bones - immunology | Osteoclasts - drug effects | Bone Demineralization, Pathologic - immunology | RANKL | TGF-β | bone | osteoclast | TNF | TNF receptor-associated factor (TRAF) | Cell Biology
Journal Article
Journal Article
FASEB Journal, ISSN 0892-6638, 2014, Volume 28, Issue 4, pp. 1756 - 1768
Intramacrophage pathogen Leishmania donovani escapes host immune response by subverting Toll-like receptor (TLR) signaling, which is critically regulated by... 
Signalosome | Ubiquitination | Macrophage | IMMUNE-RESPONSE | TOLL-LIKE-RECEPTOR-4 | ACTIVATION | PROTEIN | signalosome | BIOCHEMISTRY & MOLECULAR BIOLOGY | macrophage | CELL BIOLOGY | ubiquitination | EXPERIMENTAL VISCERAL LEISHMANIASIS | BIOLOGY | TOLL-LIKE RECEPTORS | INFECTION | PROMASTIGOTES | NF-KAPPA-B | Tumor Necrosis Factor-alpha - metabolism | Interleukin-12 - genetics | Tumor Necrosis Factor-alpha - genetics | NF-kappa B - immunology | Immunoblotting | NF-kappa B - metabolism | Leishmaniasis, Visceral - immunology | Lipopolysaccharides - immunology | Macrophages - parasitology | Signal Transduction - immunology | Ubiquitination - drug effects | RNA Interference | TNF Receptor-Associated Factor 3 - genetics | Gene Expression - immunology | Tumor Necrosis Factor-alpha - immunology | Leishmaniasis, Visceral - parasitology | Lysine - metabolism | Macrophages - immunology | Cell Line | Leishmania donovani - immunology | Leishmania donovani - physiology | Cells, Cultured | Toll-Like Receptor 4 - genetics | TNF Receptor-Associated Factor 3 - metabolism | Host-Parasite Interactions - immunology | Interleukin-12 - metabolism | Toll-Like Receptor 4 - immunology | Ubiquitination - immunology | Reverse Transcriptase Polymerase Chain Reaction | Toll-Like Receptor 4 - metabolism | Macrophages - metabolism | Models, Immunological | Animals | NF-kappa B - genetics | TNF Receptor-Associated Factor 3 - immunology | Interleukin-12 - immunology | Leishmaniasis, Visceral - genetics | Lipopolysaccharides - pharmacology | Mice | Mice, Inbred BALB C | Lysine - immunology
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 07/2017, Volume 292, Issue 28, pp. 11804 - 11814
MicroRNAs (miRNAs) are small, noncoding RNAs that post-transcriptionally regulate gene expression. For example, miRNAs repress gene expression by recruiting... 
post-translational modification (PTM) | RISC | CELLS | microRNA (miRNA) | EDD | HYPERPLASTIC-DISCS | UBIQUITIN LIGASE | DNA-DAMAGE RESPONSE | BIOCHEMISTRY & MOLECULAR BIOLOGY | BINDING-PROTEIN | DEUBIQUITINASE DUBA | PROTEIN-KINASES | FAMILY | E3 LIGASE | Toll-like receptor (TLR) | TRAF3 | Argonaute | UBR5 | p90RSK | phosphorylation | RNA-Binding Proteins - genetics | Phosphorylation | Autoantigens - metabolism | Humans | Cercopithecus aethiops | Ubiquitin-Protein Ligases - antagonists & inhibitors | MicroRNAs - metabolism | Green Fluorescent Proteins - genetics | RNA, Messenger - metabolism | Autoantigens - genetics | Recombinant Fusion Proteins - metabolism | Ribosomal Protein S6 Kinases, 90-kDa - metabolism | RNA Interference | TNF Receptor-Associated Factor 3 - genetics | RNA, Messenger - antagonists & inhibitors | HEK293 Cells | Toll-Like Receptors - metabolism | 3' Untranslated Regions | RNA-Binding Proteins - antagonists & inhibitors | Green Fluorescent Proteins - metabolism | TNF Receptor-Associated Factor 3 - antagonists & inhibitors | Signal Transduction | Ubiquitin-Protein Ligases - metabolism | TNF Receptor-Associated Factor 3 - metabolism | Animals | Ribosomal Protein S6 Kinases, 90-kDa - genetics | Protein Processing, Post-Translational | HeLa Cells | Mutation | Ubiquitin-Protein Ligases - genetics | COS Cells | RNA-Binding Proteins - metabolism | Amino Acid Substitution
Journal Article
Journal Article
Journal Article
Nature Immunology, ISSN 1529-2908, 01/2010, Volume 11, Issue 1, pp. 70 - 75
Balanced production of type I interferons and proinflammatory cytokines after engagement of Toll-like receptors (TLRs), which signal through adaptors... 
DOMAIN-CONTAINING ADAPTER | APOPTOSIS | SIGNALING PATHWAYS | INFLAMMATION | TOLL-LIKE RECEPTORS | TNF-ALPHA | INDUCTION | IMMUNOLOGY | NF-KAPPA-B | CANCER | INNATE IMMUNITY | Phosphorylation | Inhibitor of Apoptosis Proteins - genetics | Adaptor Proteins, Vesicular Transport - genetics | Immunoblotting | Adaptor Proteins, Vesicular Transport - metabolism | Ubiquitination | TNF Receptor-Associated Factor 3 - genetics | Inflammation Mediators - metabolism | Interferon Type I - metabolism | Inhibitor of Apoptosis Proteins - metabolism | TNF Receptor-Associated Factor 6 - genetics | Cytokines - genetics | Cell Line | Cytokines - metabolism | Signal Transduction | Mice, Inbred C57BL | Myeloid Differentiation Factor 88 - genetics | TNF Receptor-Associated Factor 3 - metabolism | Macrophages - cytology | Reverse Transcriptase Polymerase Chain Reaction | Toll-Like Receptor 4 - metabolism | Mice, Knockout | Gene Expression Regulation - drug effects | Macrophages - metabolism | Animals | Lipopolysaccharides - pharmacology | TNF Receptor-Associated Factor 6 - metabolism | Protein Binding | Macrophages - drug effects | Mice | Myeloid Differentiation Factor 88 - metabolism | Mitogen-Activated Protein Kinases - metabolism | Care and treatment | Cytokines | Physiological aspects | Inflammation | Genetic aspects | Research | Ubiquitin-proteasome system | Health aspects
Journal Article