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Immunological Reviews, ISSN 0105-2896, 11/2011, Volume 244, Issue 1, pp. 55 - 74
A large and diverse group of receptors utilizes the family of cytoplasmic signaling proteins known as tumor necrosis factor receptor (TNFR)‐associated factors... 
tumor necrosis factor receptor | lymphocyte activation | signal transduction | tumor necrosis factor receptor associated factor | Signal transduction | Lymphocyte activation | Tumor necrosis factor receptor associated factor | Tumor necrosis factor receptor | CPG OLIGODEOXYNUCLEOTIDES | ACTIVATED PROTEIN-KINASE | HUMAN CD40 RECEPTOR | IMMUNOLOGY | TERMINAL KINASE | LYMPHOTOXIN-BETA-RECEPTOR | TOLL-LIKE RECEPTORS | LATENT MEMBRANE-PROTEIN | FAMILY-MEMBER TALL-1 | NF-KAPPA-B | T-CELLS | Tumor Necrosis Factor-alpha - metabolism | Humans | Protein Processing, Post-Translational - genetics | Tumor Necrosis Factor-alpha - genetics | NF-kappa B - immunology | Ubiquitin - metabolism | Cell Survival - genetics | TNF Receptor-Associated Factor 5 - immunology | NF-kappa B - metabolism | Signal Transduction - immunology | T-Lymphocytes - metabolism | Myeloid Cells - immunology | TNF Receptor-Associated Factor 3 - genetics | Gene Expression - immunology | Tumor Necrosis Factor-alpha - immunology | Protein Processing, Post-Translational - immunology | B-Lymphocytes - metabolism | Receptors, Tumor Necrosis Factor - genetics | Receptors, Tumor Necrosis Factor - metabolism | TNF Receptor-Associated Factor 3 - metabolism | Signal Transduction - genetics | Ubiquitin - genetics | TNF Receptor-Associated Factor 5 - metabolism | Cell Survival - immunology | Immunity, Innate | Mice, Knockout | TNF Receptor-Associated Factor 5 - genetics | Animals | B-Lymphocytes - immunology | NF-kappa B - genetics | TNF Receptor-Associated Factor 3 - immunology | Myeloid Cells - metabolism | Protein Binding | T-Lymphocytes - immunology | Mice | Receptors, Tumor Necrosis Factor - immunology | Ubiquitin - immunology | Ubiquitin | T cells | Tumor necrosis factor | Necrosis | Tumors
Journal Article
Journal Article
Journal Article
Nature Immunology, ISSN 1529-2908, 09/2011, Volume 12, Issue 9, pp. 853 - 860
Interleukin 17 (IL-17) promotes the expression of chemokines and cytokines via the induction of gene transcription and post-transcriptional stabilization of... 
ACTIVATED PROTEIN-KINASE | NEUTROPHIL INFILTRATION | FACTOR ASF/SF2 | STABILIZATION | STABILITY | FUNCTIONAL-ANALYSIS | GENE-EXPRESSION | RECEPTOR | IMMUNOLOGY | NF-KAPPA-B | POSTTRANSCRIPTIONAL CONTROL | RNA-Binding Proteins - genetics | Alternative Splicing | Humans | Interleukin-17 - immunology | Half-Life | TNF Receptor-Associated Factor 5 - immunology | Chemokine CXCL1 - genetics | Interleukin-17 - pharmacology | RNA Stability - drug effects | Signal Transduction - immunology | Inflammation - metabolism | Th17 Cells - metabolism | Adaptor Proteins, Signal Transducing - immunology | Female | Transcription, Genetic | Chemokine CXCL1 - metabolism | Nuclear Proteins - genetics | RNA Processing, Post-Transcriptional | RNA-Binding Proteins - immunology | Nuclear Proteins - metabolism | Inflammation - immunology | TNF Receptor-Associated Factor 5 - metabolism | Nuclear Proteins - immunology | Mice, Knockout | Chemokine CXCL1 - immunology | Interleukin-17 - metabolism | TNF Receptor-Associated Factor 5 - genetics | Animals | Adaptor Proteins, Signal Transducing - genetics | Serine-Arginine Splicing Factors | Inflammation - genetics | Th17 Cells - immunology | Mice | HeLa Cells | Adaptor Proteins, Signal Transducing - metabolism | RNA, Messenger | RNA-Binding Proteins - metabolism | Physiological aspects | Messenger RNA | Research | Interleukins | Health aspects | Chemokines
Journal Article
Journal of experimental medicine, ISSN 0022-1007, 2010, Volume 207, Issue 2, pp. 391 - 404
Journal Article
Nature Immunology, ISSN 1529-2908, 11/2012, Volume 13, Issue 11, pp. 1110 - 1117
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 05/2017, Volume 114, Issue 19, pp. E3796 - E3805
Epithelial barrier disruption is a major cause of inflammatory bowel disease (IBD); however, the mechanism through which epigenetic regulation modulates... 
NF-κB | ITCH | TNFα | Colitis | EZH2 | METHYLATION | colitis | TNF alpha | MULTIDISCIPLINARY SCIENCES | ULCERATIVE-COLITIS | BIVALENT PROMOTERS | INTESTINAL HOMEOSTASIS | BOWEL-DISEASE | CELL-DEATH | LINEAGE COMMITMENT | JNK ACTIVATION | NF-kappa B | NF-KAPPA-B | INNATE IMMUNITY | Inflammation - chemically induced | Tumor Necrosis Factor-alpha - metabolism | Inflammation - pathology | Intestinal Mucosa - metabolism | Colitis - genetics | Epigenesis, Genetic | Humans | TNF Receptor-Associated Factor 2 - genetics | Tumor Necrosis Factor-alpha - genetics | Colitis - pathology | Inflammation - metabolism | Colitis - chemically induced | CASP8 and FADD-Like Apoptosis Regulating Protein - metabolism | Repressor Proteins - metabolism | Enhancer of Zeste Homolog 2 Protein - genetics | Enhancer of Zeste Homolog 2 Protein - metabolism | Signal Transduction | CASP8 and FADD-Like Apoptosis Regulating Protein - genetics | Ubiquitin-Protein Ligases - metabolism | Repressor Proteins - genetics | TNF Receptor-Associated Factor 2 - metabolism | TNF Receptor-Associated Factor 5 - metabolism | Dextran Sulfate - toxicity | Mice, Knockout | TNF Receptor-Associated Factor 5 - genetics | Animals | NF-kappa B - genetics | Colitis - metabolism | Inflammation - genetics | Mice | Ubiquitin-Protein Ligases - genetics | Apoptosis | Intestinal Mucosa - pathology | Biological Sciences | PNAS Plus
Journal Article
Journal Article
Protein Science, ISSN 0961-8368, 07/2016, Volume 25, Issue 7, pp. 1273 - 1289
Tumor necrosis factor receptor‐associated factors (TRAFs) constitute a family of adapter proteins that act in numerous signaling pathways important in human... 
protein–protein interactions | interaction specificity | deep mutational scanning | bacterial surface display | Deep mutational scanning | Interaction specificity | Protein-protein interactions | Bacterial surface display | RECEPTOR-ASSOCIATED FACTORS | SITE | DOMAIN | SPECIFICITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | IDENTIFICATION | protein-protein interactions | CD40 RECOGNITION | FAMILY | STRUCTURAL BASIS | PROTEIN FUNCTION | EPSTEIN-BARR-VIRUS | Protein Structure, Secondary | Humans | TNF Receptor-Associated Factor 2 - genetics | Models, Molecular | TNF Receptor-Associated Factor 2 - metabolism | TNF Receptor-Associated Factor 3 - metabolism | TNF Receptor-Associated Factor 3 - chemistry | TNF Receptor-Associated Factor 5 - metabolism | DNA Mutational Analysis - methods | Tumor Necrosis Factor Receptor-Associated Peptides and Proteins - metabolism | Tumor Necrosis Factor Receptor-Associated Peptides and Proteins - chemistry | TNF Receptor-Associated Factor 5 - genetics | CD40 Antigens - metabolism | Peptides - metabolism | TNF Receptor-Associated Factor 5 - chemistry | TNF Receptor-Associated Factor 3 - genetics | TNF Receptor-Associated Factor 2 - chemistry | Protein Binding | Adaptor Proteins, Signal Transducing - metabolism | Binding Sites | Tumor Necrosis Factor Receptor-Associated Peptides and Proteins - genetics | Proteins | Comparative analysis | Escherichia coli | Protein binding | Libraries | Peptides | Adapter proteins | Binding sites
Journal Article