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The Journal of Allergy and Clinical Immunology, ISSN 0091-6749, 06/2018, Volume 141, Issue 6, pp. 2027 - 2036.e12
Exacerbations of asthma and chronic obstructive pulmonary disease (COPD) are heterogeneous. We sought to investigate the sputum cellular, mediator, and... 
factor and cluster analyses | inflammatory profiles | microbiome abundances | phylum and genus levels | asthma and chronic obstructive pulmonary disease heterogeneity | Asthma | chronic obstructive pulmonary disease | asthma and chronic obstructive pulmonary disease heterogeneity | MEPOLIZUMAB | SEVERE EOSINOPHILIC ASTHMA | CONTROLLED PHASE-3 TRIAL | RANDOMIZED CONTROLLED-TRIAL | AZITHROMYCIN | IMMUNOLOGY | ALLERGY | SPUTUM EOSINOPHILIA | DOUBLE-BLIND | RHINOVIRUS INFECTION | PLACEBO-CONTROLLED TRIAL | COPD | Sputum - microbiology | Asthma - metabolism | Inflammation - microbiology | Prospective Studies | Asthma - microbiology | Pulmonary Disease, Chronic Obstructive - microbiology | Humans | Male | Inflammation - immunology | Sputum - metabolism | Inflammation - metabolism | Microbiota | Sputum - immunology | Asthma - immunology | Adult | Female | Pulmonary Disease, Chronic Obstructive - metabolism | Pulmonary Disease, Chronic Obstructive - immunology | Medicine, Experimental | Medical research | Analysis | Tumor necrosis factor receptors | Microbiomes | Viruses | Parameter identification | Blood | Subgroups | Interleukin 6 | Receptors | Microorganisms | Interleukin 5 | Interleukin 6 receptors | Chronic obstructive pulmonary disease | Vascular endothelial growth factor | CCL17 protein | Lung diseases | Interleukin 13 | Inflammation | Tumor necrosis factor-α | Clustering | Patients | Quality of life | Respiratory syncytial virus | Influenza | γ-Interferon | Obstructive lung disease | CXCL10 protein | Sputum | CXCL11 protein | F ratio, Proteobacteria | COPD, Chronic obstructive pulmonary disease | VEGF, Vascular endothelial growth factor | Firmicutes ratio | IL-6R, IL-6 receptor | TNF-R, TNF receptor | VAS, Visual analog scale | T2, Type 2 | T1, Type 1
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 10/2015, Volume 466, Issue 1, pp. 1 - 14
Immunoblotting is a powerful technique for the semi-quantitative analysis of ubiquitylation events, and remains the most commonly used method to study this... 
Ubiquitin | Ubiquitin-binding-domain | Immunoblotting | Ubiquitin chain topology | Deubiquitylase | KAPPA-B ACTIVATION | C-TERMINUS | SPECIFICITY | RECOGNITION | BIOCHEMISTRY & MOLECULAR BIOLOGY | POLYUBIQUITIN-BINDING | TAGGED UBIQUITIN | MASS-SPECTROMETRY | BIOPHYSICS | STRUCTURAL BASIS | TNF-ALPHA | MONOCLONAL-ANTIBODIES | Ubiquitin - analysis | Up-Regulation | Immunoprecipitation - methods | Humans | Ubiquitin - metabolism | Ubiquitin - genetics | Ubiquitinated Proteins - analysis | Electrophoresis, Polyacrylamide Gel - methods | Immunoblotting - methods | Ubiquitination | Animals | Ubiquitin-Specific Proteases - metabolism | Ubiquitinated Proteins - metabolism | Binding proteins | Analysis | Methods | Protein binding | Phosphatases | Polyvinylidene fluoride | Interleukins | Glutathione transferase | DNA binding proteins | Glycine | NEMO, NF-κB essential modulator | TNF, tumour necrosis factor | IAA, iodoacetamide | NC, nitrocellulose | HEK, human embryonic kidney | MOPS, 3-(N-morpholino) propane sulfonic acid | UBA, ubiquitin-associated | TUBEs, tandem-repeated ubiquitin-binding entities | TA, tris-acetate | IRAK, interleukin receptor associated kinase | PPase, phage λ-phosphatase | RIP, receptor interacting protein | DUB, deubiquitylase | DMP, dimethyl pimelidinate | TG, tris-glycine | pUb, polyubiquitin | PVDF, polyvinyl difluoride | SDS, sodium dodecyl sulphate | IMAC, immobilised metal ion affinity chromatography | NEM, N-ethylmaleimide | GST, glutathione S-transferase | Mini Review | LUBAC, Linear UBiquitin Assembly Complex | IP, immunoprecipitation | POI, protein of interest | MES, 2-(N-morpholino) ethane sulfonic acid | IL-1R, IL-1 receptor | TNF-R, TNF receptor | UBD, ubiquitin-binding domain | UBAN, ubiquitin binding in ABIN and NEMO domain | UIM, ubiquitin-interacting motif | NZF, Npl4 zinc finger
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 04/2002, Volume 22, Issue 7, pp. 216 - RC216
Tumor necrosis factor (TNF) is an important factor in various acute and chronic neurodegenerative disorders. In retinal ischemia, we show early, transient... 
retinal cell layers | MONOCYTOGENES | RAT | knock-out mouse | NEUROSCIENCES | MICE LACKING | ischemia | immunohistology | FACTOR-ALPHA | neuronal TNF and TNF-R expression | RESISTANT | INHIBITION | neuroprotection | IN-VIVO | BRAIN INJURY | CEREBRAL-ISCHEMIA | Akt/PKB activation | LYMPHOTOXIN | Tumor Necrosis Factor-alpha - metabolism | Neurons - pathology | Up-Regulation | Cell Count | Protein-Serine-Threonine Kinases | Tumor Necrosis Factor-alpha - genetics | Phosphatidylinositol 3-Kinases - metabolism | Tumor Necrosis Factor-alpha - deficiency | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Antigens, CD - genetics | Antigens, CD - metabolism | Retinal Vessels - pathology | Retina - enzymology | Receptors, Tumor Necrosis Factor, Type II | Cytoprotection - drug effects | Retinal Diseases - pathology | Receptors, Tumor Necrosis Factor - deficiency | Cell Death - drug effects | Neurons - drug effects | Disease Models, Animal | Receptors, Tumor Necrosis Factor - genetics | Proto-Oncogene Proteins - metabolism | Receptors, Tumor Necrosis Factor - metabolism | Reperfusion Injury - pathology | Receptors, Tumor Necrosis Factor, Type I | Retina - physiopathology | Blotting, Western | Mice, Knockout | Proto-Oncogene Proteins c-akt | Tumor Necrosis Factor-alpha - pharmacology | Animals | Signal Transduction - drug effects | Reperfusion Injury - physiopathology | Retinal Vessels - physiopathology | Cytoprotection - genetics | Mice | Retinal Diseases - drug therapy | Retinal Diseases - physiopathology | Retina - pathology
Journal Article
Toxicology Reports, ISSN 2214-7500, 10/2014, Volume 1, Issue C, pp. 1062 - 1067
The circulating soluble tumor necrosis factor (sTNF) and sTNF-receptor (R) 1 and -R2 have known as septic biomarker. The pungent component of capsicum,... 
Soluble tumor necrosis factor-receptor 1 and 2 (TNF-R 1 and 2) | ADAM-17 | TNF-converting enzyme (TACE) | Soluble tumor necrosis (sTNF) | Capsaicin | Lipopolysaccharide (LPS)
Journal Article
International immunology, ISSN 0953-8178, 2007, Volume 19, Issue 6, pp. 713 - 718
Journal Article
Journal Article
Journal Article
Trends in Immunology, ISSN 1471-4906, 2001, Volume 22, Issue 5, pp. 260 - 264
Recent studies of Drosophila immune responses have defined the immune deficiency (IMD) signaling pathway that mediates defense against Gram-negative bacterial... 
NF-kappa B | drosophila | signal transduction | immunity | immune defeciency | toll | TNF-R pathway | IMD pathway | MELANOGASTER CELLS | RECOGNITION | SIGNALING PATHWAY | ANTIMICROBIAL PEPTIDE GENES | HOST-DEFENSE | RELISH | INDUCTION | IMMUNOLOGY | TOLL | EXPRESSION | INNATE IMMUNITY
Journal Article
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