X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (4754) 4754
Book Review (664) 664
Publication (425) 425
Book Chapter (37) 37
Conference Proceeding (13) 13
Dissertation (7) 7
Data Set (1) 1
Journal / eJournal (1) 1
Web Resource (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (3825) 3825
tnf-α (2498) 2498
humans (2408) 2408
tnf-alpha (2194) 2194
animals (1966) 1966
male (1445) 1445
tumor necrosis factor-alpha - antagonists & inhibitors (1322) 1322
female (1067) 1067
mice (1005) 1005
tumor necrosis factor-alpha - metabolism (911) 911
tumor-necrosis-factor (894) 894
inflammation (892) 892
rats (745) 745
pharmacology & pharmacy (730) 730
immunology (712) 712
tnfα (684) 684
biochemistry & molecular biology (646) 646
necrosis-factor-alpha (607) 607
expression (602) 602
cytokines (592) 592
middle aged (591) 591
adult (571) 571
cell biology (555) 555
cells, cultured (549) 549
infliximab (548) 548
rheumatoid-arthritis (521) 521
tnf alpha (509) 509
tumor necrosis factor-alpha - pharmacology (492) 492
rheumatology (473) 473
rheumatoid arthritis (462) 462
activation (447) 447
etanercept (421) 421
nf-kappa-b (420) 420
apoptosis (391) 391
neurosciences (371) 371
tumor necrosis factor-alpha - genetics (355) 355
il-6 (347) 347
aged (341) 341
tumor necrosis factor-alpha - biosynthesis (322) 322
cell line (321) 321
il-1β (310) 310
nf-kappa b - metabolism (309) 309
dose-response relationship, drug (307) 307
antibodies, monoclonal - therapeutic use (306) 306
adalimumab (304) 304
cells (302) 302
medicine & public health (293) 293
arthritis, rheumatoid - drug therapy (290) 290
tumor necrosis factor-alpha - immunology (282) 282
rats, sprague-dawley (280) 280
therapy (273) 273
antirheumatic agents - therapeutic use (272) 272
nf-κb (272) 272
disease models, animal (267) 267
treatment outcome (266) 266
tumor necrosis factor-α (266) 266
tumor necrosis factor (263) 263
tnf (262) 262
lipopolysaccharides - pharmacology (260) 260
gene-expression (258) 258
article (253) 253
tnf‐α (250) 250
mice, inbred c57bl (249) 249
il-1 beta (245) 245
internal medicine (237) 237
time factors (237) 237
analysis (232) 232
macrophages (229) 229
nf-kappa b (219) 219
signal transduction (219) 219
chemistry, medicinal (217) 217
in-vitro (217) 217
arthritis (212) 212
inhibition (212) 212
rats, wistar (212) 212
factor-alpha (211) 211
oxidative stress (201) 201
receptor (200) 200
apoptosis - drug effects (198) 198
lipopolysaccharide (197) 197
medicine, research & experimental (197) 197
rna, messenger - metabolism (197) 197
disease (196) 196
phosphorylation (195) 195
signal transduction - drug effects (193) 193
anti-inflammatory agents - pharmacology (190) 190
biophysics (188) 188
enzyme-linked immunosorbent assay (187) 187
oncology (184) 184
cytokines - metabolism (183) 183
enzyme inhibitors - pharmacology (180) 180
tumor necrosis factor-alpha - physiology (177) 177
cell line, tumor (174) 174
cytokine (161) 161
anti-tnf-α (160) 160
mice, inbred balb c (160) 160
tumor necrosis factor-alpha (160) 160
crohns-disease (159) 159
nitric oxide (159) 159
research (158) 158
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (4656) 4656
German (44) 44
French (33) 33
Japanese (18) 18
Korean (10) 10
Spanish (9) 9
Polish (6) 6
Portuguese (5) 5
Chinese (2) 2
Croatian (2) 2
Czech (2) 2
Italian (2) 2
Arabic (1) 1
Estonian (1) 1
Hungarian (1) 1
Russian (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


British Journal of Pharmacology, ISSN 0007-1188, 06/2013, Volume 169, Issue 4, pp. 808 - 819
Background and purpose JZL184 is a selective inhibitor of monoacylglycerol lipase (MAGL), the enzyme that preferentially catabolizes the endocannabinoid... 
monoacylglycerol lipase | endocannabinoid | | frontal cortex | NF‐κB | cytokines | brain | plasma | JZL | 184 | TNF | 10 | IL-1β | IL-10 | IL-6 | JZL184 | NF-κB | TNF-α | 2-AG | ACTIVATED RECEPTOR-GAMMA | IL-1 | 2-ARACHIDONYL GLYCEROL | NF-B | NECROSIS-FACTOR-ALPHA | MICROGLIAL CELLS | ARRIVE GUIDELINES | CANNABINOID RECEPTORS | ENDOCANNABINOID 2-ARACHIDONOYLGLYCEROL | COX-2 EXPRESSION | IN-VIVO | PHARMACOLOGY & PHARMACY | NF-KAPPA-B | Benzodioxoles - antagonists & inhibitors | Spleen - immunology | Frontal Lobe - metabolism | Male | Spleen - drug effects | Prostaglandins - blood | Lipopolysaccharides | Monoacylglycerol Lipases - metabolism | Arachidonic Acids - metabolism | Glycerides - blood | Arachidonic Acids - blood | Enzyme Inhibitors - chemistry | Anti-Anxiety Agents - therapeutic use | Benzodioxoles - therapeutic use | Peritonitis - metabolism | Rats | Encephalitis - immunology | Random Allocation | Glycerides - metabolism | Enzyme Inhibitors - therapeutic use | Rats, Sprague-Dawley | Cannabinoid Receptor Antagonists - therapeutic use | Monoacylglycerol Lipases - blood | Peritonitis - drug therapy | Receptor, Cannabinoid, CB1 - antagonists & inhibitors | Endocannabinoids - metabolism | Nerve Tissue Proteins - blood | Monoacylglycerol Lipases - antagonists & inhibitors | Piperidines - antagonists & inhibitors | Receptor, Cannabinoid, CB2 - antagonists & inhibitors | Anti-Inflammatory Agents, Non-Steroidal - antagonists & inhibitors | Encephalitis - drug therapy | Encephalitis - metabolism | Cytokines - blood | Nerve Tissue Proteins - antagonists & inhibitors | Cytokines - metabolism | Peritonitis - immunology | Nerve Tissue Proteins - metabolism | Receptor, Cannabinoid, CB1 - metabolism | Receptor, Cannabinoid, CB2 - metabolism | Animals | Spleen - metabolism | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Piperidines - therapeutic use | Frontal Lobe - drug effects | Cannabinoid Receptor Antagonists - chemistry | Frontal Lobe - immunology | Cytokines - antagonists & inhibitors | Endocannabinoids - blood | Prostaglandins - metabolism | Glycerin | Brain | Unsaturated fatty acids | Cytokines | Glycerol | Lipase | Mitogens | Plasma | Rodents | Index Medicus | Cannabinoids 2012, Part Two | Themed Section
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 03/2013, Volume 168, Issue 6, pp. 1388 - 1400
Background and Purpose Chemotherapeutic agents, including 5-fluorouracil (5-FU), frequently cause intestinal mucositis resulting in severe diarrhoea and... 
receptors | ondansetron | caspase‐8 | intestinal mucositis | ramosetron | apoptosis | 5‐fluorouracil | TNF | caspase‐3 | RECOMMENDED GUIDELINES | caspase-8 | INDUCED DIARRHEA | CANCER | CHEMOTHERAPY | 5-fluorouracil | PATHOGENESIS | DISTAL COLON | EXPERIMENTAL COLITIS | EPITHELIAL-CELLS | 5-HT3 receptors | PHARMACOLOGY & PHARMACY | SEROTONIN | EXPRESSION | caspase-3 | Mucositis - metabolism | Intestinal Mucosa - metabolism | Apoptosis - drug effects | Colonic Neoplasms - drug therapy | Immunosuppressive Agents - therapeutic use | Gastrointestinal Agents - administration & dosage | Diarrhea - prevention & control | Male | Fluorouracil - antagonists & inhibitors | Mucositis - prevention & control | Intestinal Mucosa - drug effects | Serotonin 5-HT3 Receptor Antagonists - administration & dosage | Dose-Response Relationship, Drug | Fluorouracil - therapeutic use | Mucositis - pathology | Drug Interactions | Benzimidazoles - administration & dosage | Fluorouracil - adverse effects | Intestinal Mucosa - immunology | Apoptosis Regulatory Proteins - genetics | Benzimidazoles - adverse effects | Cytokines - genetics | Benzimidazoles - therapeutic use | Cytokines - metabolism | Mice, Inbred C57BL | Immunosuppressive Agents - antagonists & inhibitors | Mucositis - chemically induced | Apoptosis Regulatory Proteins - metabolism | Gene Expression Regulation - drug effects | Serotonin 5-HT3 Receptor Antagonists - therapeutic use | Antimetabolites, Antineoplastic - therapeutic use | Animals | Ondansetron - therapeutic use | Serotonin 5-HT3 Receptor Antagonists - adverse effects | Antimetabolites, Antineoplastic - adverse effects | Apoptosis Regulatory Proteins - antagonists & inhibitors | Gastrointestinal Agents - therapeutic use | Diarrhea - etiology | Immunosuppressive Agents - adverse effects | Mice | Ondansetron - adverse effects | Serotonin 5-HT3 Receptor Agonists - therapeutic use | Intestinal Mucosa - pathology | Serotonin 5-HT3 Receptor Agonists - adverse effects | Chemotherapy | Nausea | Cancer | Fluorouracil | Apoptosis | Index Medicus | Research Papers | TNF-α
Journal Article
International Journal of Molecular Sciences, ISSN 1661-6596, 11/2016, Volume 17, Issue 11, pp. 1869 - 1869
Tumor necrosis factor receptor-associated factor 2 (TRAF2) is a critical mediator of tumor necrosis factor-alpha (TNF-alpha) signaling. However, the regulatory... 
TRAF2 | JNK | Tumor necrosis factor-α (TNF-α) | BIG1 | Apoptosis | APOPTOSIS | LOCALIZATION | ACTIVATION | PROTEIN | NECROPTOSIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | tumor necrosis factor-alpha (TNF-alpha); apoptosis | CHEMISTRY, MULTIDISCIPLINARY | CELL-DEATH | ADP-RIBOSYLATION FACTORS | RECYCLING ENDOSOMES | ARF-FAMILY | NF-KAPPA-B | RNA, Small Interfering - genetics | Luciferases - metabolism | Apoptosis - drug effects | Humans | TNF Receptor-Associated Factor 2 - genetics | JNK Mitogen-Activated Protein Kinases - metabolism | NF-kappa B - metabolism | Receptors, Tumor Necrosis Factor, Type I - metabolism | Luciferases - genetics | Proteolysis - drug effects | Ubiquitination - drug effects | Guanine Nucleotide Exchange Factors - metabolism | JNK Mitogen-Activated Protein Kinases - genetics | Genes, Reporter | Guanine Nucleotide Exchange Factors - genetics | NF-kappa B - antagonists & inhibitors | JNK Mitogen-Activated Protein Kinases - antagonists & inhibitors | Gene Expression Regulation | TNF Receptor-Associated Factor 2 - metabolism | Signal Transduction - genetics | Receptors, Tumor Necrosis Factor, Type I - antagonists & inhibitors | Receptors, Tumor Necrosis Factor, Type I - genetics | Protein Transport | TNF Receptor-Associated Factor 2 - antagonists & inhibitors | Tumor Necrosis Factor-alpha - pharmacology | Guanine Nucleotide Exchange Factors - antagonists & inhibitors | NF-kappa B - genetics | Cell Line, Tumor | Protein Binding | HeLa Cells | RNA, Small Interfering - metabolism | Signal transduction | Tumor necrosis factor-TNF | Adenosine triphosphatase | Index Medicus | apoptosis | tumor necrosis factor-α (TNF-α)
Journal Article
Clinical and Experimental Rheumatology, ISSN 0392-856X, 2011, Volume 29, Issue 2, pp. S40 - S45
Journal Article
Journal of Molecular and Cellular Cardiology, ISSN 0022-2828, 2014, Volume 72, pp. 85 - 94
Abstract Tumor necrosis factor-α (TNF-α) is an established pro-atherosclerotic factor, but the mechanism is not completely understood. We explored whether... 
Cardiovascular | NF-κB | TNF-α | LDL | PPAR-γ | Atherosclerosis | CARDIAC & CARDIOVASCULAR SYSTEMS | ANTAGONIST | TNF-alpha | LOW-DENSITY-LIPOPROTEIN | PPAR-gamma | CELL BIOLOGY | TUMOR-NECROSIS-FACTOR | TRANSPORT | NF-kappa B | INHIBITION | E-KNOCKOUT MICE | INFLAMMATION | ACTIVATED-RECEPTOR-GAMMA | EXPRESSION | CAVEOLIN-1 | Tumor Necrosis Factor-alpha - metabolism | RNA, Small Interfering - genetics | Human Umbilical Vein Endothelial Cells - metabolism | Nitriles - pharmacology | Atherosclerosis - genetics | Humans | NF-kappa B - metabolism | Filipin - pharmacology | PPAR gamma - metabolism | Sulfones - pharmacology | Caveolin 2 - antagonists & inhibitors | Thiocarbamates - pharmacology | Human Umbilical Vein Endothelial Cells - cytology | Proline - pharmacology | Benzamides - pharmacology | Lipoproteins, LDL - metabolism | PPAR gamma - genetics | Caveolin 1 - antagonists & inhibitors | Receptors, LDL - genetics | Atherosclerosis - pathology | NF-kappa B - antagonists & inhibitors | Human Umbilical Vein Endothelial Cells - drug effects | Proline - analogs & derivatives | Signal Transduction | Atherosclerosis - chemically induced | Receptors, LDL - antagonists & inhibitors | Gene Expression Regulation | Caveolin 1 - genetics | Receptors, LDL - metabolism | Mice, Knockout | Caveolin 1 - metabolism | Caveolin 2 - metabolism | Cinchona Alkaloids - pharmacology | Tumor Necrosis Factor-alpha - pharmacology | Animals | PPAR gamma - antagonists & inhibitors | Lipoproteins, LDL - antagonists & inhibitors | NF-kappa B - genetics | Anilides - pharmacology | Mice | Pyridines - pharmacology | Transcytosis - drug effects | Caveolin 2 - genetics | Atherosclerosis - prevention & control | RNA, Small Interfering - metabolism | Index Medicus
Journal Article
Journal Article