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The Journal of Allergy and Clinical Immunology, ISSN 0091-6749, 09/2017, Volume 140, Issue 3, pp. 809 - 821.e3
Hypertension is considered an immunologic disorder. However, the role of the IL-17 family in genetic hypertension in the spontaneously hypertensive rat (SHR)... 
Hypertension | CD161 | IL-17 | spontaneously hypertensive rat | digoxin | T cells | retinoic acid receptor–related orphan receptor γt | TH17 | Toll-like receptor | gene expression | innate immune system | T | 17 | INTERLEUKIN 17 | ACTIVATION | ENDOTHELIAL DYSFUNCTION | ORGAN DAMAGE | IMMUNOLOGY | NICOTINIC ACETYLCHOLINE-RECEPTORS | RESPONSES | ALLERGY | INFLAMMATION | T(H)17 | retinoic acid receptor-related orphan receptor gamma t | DIFFERENTIATION | TH17 CELLS | LYMPHOCYTES | Animals, Newborn | Rats, Inbred SHR | Nuclear Receptor Subfamily 1, Group F, Member 3 - immunology | Nuclear Receptor Subfamily 1, Group F, Member 3 - antagonists & inhibitors | Poly I-C - pharmacology | Cells, Cultured | Interleukin-17 - immunology | Interleukin-17 - physiology | Interleukin-17 - genetics | Rats, Inbred WKY | Male | Hypertension - immunology | Spleen - cytology | Toll-Like Receptor 3 - agonists | NK Cell Lectin-Like Receptor Subfamily B - immunology | Digoxin - pharmacology | Hypertension - physiopathology | Vasodilation | Aging - immunology | Animals | Aorta, Thoracic - physiology | Blood Pressure - drug effects | Nuclear Receptor Subfamily 1, Group F, Member 3 - genetics | RNA - metabolism | Flow cytometry | Transcription factors | Digoxin | Disease | Helper cells | Nervous system | Lymphocytes T | Birth | Kinases | Signal transduction | Splenocytes | Lymphocytes | Rodents | Measurement methods | Blood pressure | Immune system | Spleen | Immune response | Cytokines | Rats | Pharmacology | Inflammation | T cell receptors | Interleukin 17 | Endothelium | Immune systems | Acids | Prostate | Surface markers | Retinoic acid | Nicotine | Index Medicus | Abridged Index Medicus
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2015, Volume 137, Issue 6, pp. 1841 - 1851.e2
Background Dendritic cells (DCs) are key players in the induction and re-elicitation of TH 2 responses to allergens. We have previously shown that different... 
Allergy and Immunology | aryl-hydrocarbon receptor | nuclear factor κB | Dendritic cells | Toll-like receptor 4 | allergy | C-type lectin receptor | indoleamine 2,3-dioxygenase | mannose receptor | TH2 | 2 | T | nuclear factor kappa B | EXPERIMENTAL ASTHMA | IDO ACTIVITY | IMMUNOLOGY | HOUSE-DUST MITE | HUMAN MONOCYTES | T(H)2 | IN-VITRO | NONINTEGRIN DC-SIGN | CYTOKINE PRODUCTION | ALLERGIC SENSITIZATION | MOUSE MODEL | NF-KAPPA-B | Indoleamine-Pyrrole 2,3,-Dioxygenase - metabolism | Mannose-Binding Lectins - metabolism | T-Lymphocytes, Helper-Inducer - metabolism | Cytokines - metabolism | Signal Transduction | Monocytes - cytology | Dendritic Cells - immunology | Humans | Receptors, Cell Surface - metabolism | Monocytes - metabolism | Gene Expression Profiling | Monocytes - immunology | Toll-Like Receptor 4 - metabolism | Lectins, C-Type - metabolism | Lymphocyte Activation - immunology | Allergens - immunology | T-Lymphocytes, Helper-Inducer - immunology | Receptors, Aryl Hydrocarbon - metabolism | Toll-Like Receptor 4 - agonists | Ligands | Dendritic Cells - metabolism | Cluster Analysis | Interleukin-12 - biosynthesis | Allergens | Allergy | Lectins | Allergic reaction | Sugars | Monosaccharides | Immunoglobulins | Transcription factors | Metabolites | Cloning | Hydrocarbons | Kinases | Allergies | Asthma | Index Medicus | Abridged Index Medicus
Journal Article
Journal of Immunology, ISSN 0022-1767, 04/2011, Volume 186, Issue 8, pp. 4794 - 4804
Endosomal TLRs play an important role in innate immune response as well as in autoimmune processes. In the therapy of systemic lupus erythematosus,... 
IMMUNOSTIMULATORY CPG-OLIGODEOXYNUCLEOTIDES | CELLS | SYSTEMIC-LUPUS-ERYTHEMATOSUS | ACTIVATION | DNA | COMPLEXES | TOLL-LIKE RECEPTORS | H+-ATPASE | IFN-ALPHA INDUCER | IMMUNOLOGY | NUCLEIC-ACIDS | Humans | Toll-Like Receptor 9 - genetics | Toll-Like Receptor 3 - antagonists & inhibitors | Endosomes - metabolism | Quinolines - pharmacology | Chloroquine - pharmacology | Quinacrine - pharmacology | Transfection | Hydrogen-Ion Concentration - drug effects | HEK293 Cells | Toll-Like Receptors - antagonists & inhibitors | Toll-Like Receptor 3 - genetics | Culture Media - chemistry | Imidazoles - metabolism | Toll-Like Receptor 8 - agonists | Binding, Competitive | Toll-Like Receptor 7 - agonists | Toll-Like Receptor 7 - genetics | Cell Line | Antimalarials - metabolism | Toll-Like Receptor 7 - metabolism | Toll-Like Receptor 9 - antagonists & inhibitors | Cytokines - metabolism | Cells, Cultured | Imidazoles - pharmacology | Nucleic Acids - metabolism | Toll-Like Receptor 3 - metabolism | Toll-Like Receptors - agonists | Antimalarials - pharmacology | Quinolines - metabolism | Animals | Toll-Like Receptors - genetics | Culture Media - pharmacology | Toll-Like Receptor 8 - genetics | Endosomes - chemistry | Toll-Like Receptor 9 - metabolism | Toll-Like Receptor 8 - metabolism | Serum - chemistry | Index Medicus | Abridged Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2011, Volume 108, Issue 50, pp. 20054 - 20059
We report here that mouse macrophages undergo receptor-interacting kinase-3 (RIP3)-dependent but TNF-α—independent necrosis when Toll-like receptors (TLR) 3... 
Reactive oxygen species | Receptors | Cytokines | Cell death | Toll like receptors | Mice | Macrophages | Viability | Necrosis | Apoptosis | Necroptosis | Bone marrow-derived macrophage | INDUCED CELL-DEATH | APOPTOSIS | DOMAIN | PROTEIN | RECOGNITION | MULTIDISCIPLINARY SCIENCES | INHIBITION | LIPOPOLYSACCHARIDE | MICE | TNF-ALPHA | bone marrow-derived macrophage | NF-KAPPA-B | necroptosis | Protein Structure, Tertiary | Receptor-Interacting Protein Serine-Threonine Kinases - metabolism | Reactive Oxygen Species - metabolism | Macrophages - pathology | Receptor-Interacting Protein Serine-Threonine Kinases - chemistry | NF-kappa B - metabolism | Enzyme Activation - drug effects | Toll-Like Receptor 3 - metabolism | Adaptor Proteins, Vesicular Transport - metabolism | Toll-Like Receptor 4 - metabolism | Mice, Knockout | Signal Transduction - immunology | Models, Immunological | Animals | Signal Transduction - drug effects | Protein Binding - drug effects | Inflammation Mediators - metabolism | Lipopolysaccharides - pharmacology | Interferon Regulatory Factor-3 - metabolism | Macrophages - drug effects | Cytokines - biosynthesis | Macrophages - immunology | Cell receptors | Genetic aspects | Properties | Gangrene | Signal transduction | TNF inhibitors | Kinases | Rodents | Index Medicus | Tumor necrosis factor receptors | Immune response | Data processing | Inflammation | Interleukin 1 receptors | TLR4 protein | adaptor proteins | TLR3 protein | Lipopolysaccharides | Infection | beta -Interferon | Toll-like receptors | Biological Sciences
Journal Article
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 08/2014, Volume 130, Issue 4, pp. 563 - 574
Journal Article