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Journal of Hepatology, ISSN 0168-8278, 2015, Volume 63, Issue 2, pp. 320 - 328
Journal Article
Journal Article
American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 07/2016, Volume 194, Issue 1, pp. 1 - 3
Journal Article
Annals of the Rheumatic Diseases, ISSN 0003-4967, 06/2018, Volume 77, Issue Suppl 2, p. 741
BackgroundType I interferon (IFN)-regulated proteins are upregulated in muscle and skin tissues of patients with idiopathic inflammatory myopathies (IIM).1... 
Immunization | TLR7 protein | Autoantibodies | Dermatomyositis | Arthritis | Inflammation | Leukocytes | Ribonucleic acid--RNA | TLR3 protein | Skeletal muscle | Major histocompatibility complex | Toll-like receptors | Myositis | Histocompatibility antigen HLA | Skin | Interferon
Journal Article
Journal Article
Journal of the American Society of Nephrology, ISSN 1046-6673, 06/2007, Volume 18, Issue 6, pp. 1721 - 1731
Journal Article
Journal Article
Cellular Signalling, ISSN 0898-6568, 11/2013, Volume 25, Issue 11, pp. 2093 - 2105
The precise mechanism(s) by which intracellular TOLL-like receptors (TLRs) become activated by their ligands remains unclear. Here, we report a molecular... 
TLR signaling | GPCR Gα proteins | Macrophage cells | Neu1 sialidase | MMP9 | NMBR receptors | GPCR signaling | G-ALPHA(I) PROTEINS | DENDRITIC CELLS | CPG-DNA | SURFACE EXPRESSION | PROTEIN-COUPLED RECEPTORS | MEMBRANE TRAFFICKING | CELL BIOLOGY | GROWTH-FACTOR RECEPTOR | GPCR G alpha proteins | IN-VIVO | LIPOPOLYSACCHARIDE | NF-KAPPA-B | RNA, Small Interfering - genetics | Humans | Receptors, Bombesin - genetics | Toll-Like Receptor 9 - genetics | Neuraminidase - genetics | NF-kappa B - metabolism | Endosomes - metabolism | Inflammation - metabolism | Matrix Metalloproteinase 9 - metabolism | Oligonucleotides - pharmacology | Matrix Metalloproteinase 9 - genetics | HEK293 Cells | Aminoquinolines - pharmacology | Oseltamivir - pharmacology | Toll-Like Receptor 7 - genetics | Cell Line | Toll-Like Receptor 7 - metabolism | Enzyme Inhibitors - pharmacology | Gene Expression Regulation | Neuraminidase - metabolism | Signal Transduction - genetics | Macrophages - cytology | Receptors, Bombesin - antagonists & inhibitors | Macrophages - metabolism | Receptors, Bombesin - metabolism | Animals | NF-kappa B - genetics | Inflammation - genetics | Macrophages - drug effects | Neuraminidase - antagonists & inhibitors | Mice | Toll-Like Receptor 9 - metabolism | Interferon Inducers - pharmacology | RNA, Small Interfering - metabolism | Nucleic acids | Immune systems | Proteins | Platforms | Cellular | Receptors | Inhibitors | Ligands | Activation
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2015, Volume 10, Issue 8, p. e0134640
Background Newborns and young infants are at higher risk for infections than adults, and manifest sub-optimal vaccine responses, motivating a search for novel... 
SURVIVAL | RESPONSES | IMMUNIZATION | EARLY-LIFE | MULTIDISCIPLINARY SCIENCES | DISTINCT | INFECTION | MECHANISMS | VACCINE ADJUVANTS | CHALLENGES | INNATE IMMUNITY | Toll-Like Receptor 7 - agonists | Cytokines - metabolism | Recombinant Fusion Proteins - pharmacology | Humans | Imidazoles - pharmacology | Fetal Blood - cytology | Fetal Blood - drug effects | Fetal Blood - metabolism | Quinolines - pharmacology | Pregnancy | Up-Regulation - drug effects | HEK293 Cells | Adult | Dendritic Cells - drug effects | Female | Leukocytes - drug effects | Immunosuppressive Agents - pharmacology | Leukocytes - metabolism | Dendritic Cells - metabolism | Infant, Newborn | Toll-Like Receptor 8 - agonists | Neonates | Congeners | Infants | Lymphocytes T | Vaccines | Leukocytes | Crystallography | Blood | Medical schools | X-ray crystallography | Proteins | Ethics | Newborn babies | Cord blood | Peripheral blood | Toll-like receptors | Tumor necrosis factor-TNF | Immunomodulators | Pharmaceutical sciences | Enzyme-linked immunosorbent assay | Age | Carbonyls | Immune system | NF-κB protein | Immunization | Adenosine | Oxygen | TLR7 protein | Cytokines | Immunomodulation | Health risks | Adjuvants | Tumor necrosis factor-α | IL-1β | Electrostatic properties | White blood cells | Monocytes | Hospitals | Infectious diseases | Adults
Journal Article
World Journal of Gastroenterology, ISSN 1007-9327, 07/2015, Volume 21, Issue 26, pp. 8052 - 8060
AIM: To investigate the effects of our tumor vaccines on reversing immune tolerance and generating therapeutic response. METHODS: Vaccines were synthesized by... 
Monoclonal gastric cancer 7 antigen | Vaccine | Gastric cancer | Toll-like receptor-7 | Immunotherapy | TRIAL | RESPONSES | IMMUNITY | ADJUVANTS | RISK | GASTROENTEROLOGY & HEPATOLOGY | ADOPTIVE IMMUNOTHERAPY | Tumor Escape - drug effects | Membrane Glycoproteins - metabolism | Cancer Vaccines - pharmacology | Immunoconjugates - administration & dosage | Cancer Vaccines - chemical synthesis | T-Lymphocytes, Cytotoxic - drug effects | Immunoconjugates - pharmacology | Time Factors | Toll-Like Receptor 7 - immunology | Carcinoma, Ehrlich Tumor - immunology | Female | Immunization Schedule | Lymphocytes, Tumor-Infiltrating - metabolism | Membrane Glycoproteins - immunology | Carcinoma, Ehrlich Tumor - pathology | T-Lymphocytes, Cytotoxic - immunology | Toll-Like Receptor 7 - agonists | Toll-Like Receptor 7 - metabolism | Antibody-Dependent Cell Cytotoxicity | Cytokines - metabolism | Antigens, Neoplasm - immunology | Cancer Vaccines - administration & dosage | Cells, Cultured | Injections, Intraperitoneal | Membrane Glycoproteins - agonists | Carcinoma, Ehrlich Tumor - drug therapy | Epitopes | Lymphocytes, Tumor-Infiltrating - drug effects | Tumor Burden | Cancer Vaccines - immunology | Animals | Signal Transduction - drug effects | T-Lymphocytes, Cytotoxic - metabolism | Superantigens | Mice, Inbred BALB C | Lymphocytes, Tumor-Infiltrating - immunology | Basic Study
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2017, Volume 12, Issue 2, p. e0171003
Reduced immune activation or immunosuppression is seen in patients withneurological diseases. Urinary and respiratory infections mainly manifested as... 
C-REACTIVE PROTEIN | MORTALITY | OXIDATIVE STRESS | PATTERN-RECOGNITION | MULTIDISCIPLINARY SCIENCES | SCI | SYSTEM FUNCTION | CHRONIC INFLAMMATION | INNATE IMMUNITY | Leukocytes, Mononuclear - metabolism | Toll-Like Receptor 7 - metabolism | Cross-Sectional Studies | Cytokines - metabolism | Spinal Cord Injuries - metabolism | Immunomodulation | Lymphocyte Activation | Humans | Immunity | Case-Control Studies | Spinal Cord Injuries - pathology | Leukocytes, Mononuclear - immunology | Biomarkers | Ligands | Spinal Cord Injuries - immunology | Spinal Cord Injuries - rehabilitation | Leukocyte Count | Toll-Like Receptor 9 - metabolism | Chronic Disease | TLR9 | Disease susceptibility | Spinal cord injuries | TLR7 | Immune response | Research | Flow cytometry | Oxidative stress | Neurosciences | Spinal cord | Ionomycin | Stimulation | Nervous system | Lymphocytes T | Infections | Activation | Spinal cord injury | Lipopolysaccharides | Interleukin 6 | Stimulants | Education | Interleukin 1 | Toll-like receptors | Injuries | Inducers | Immune system | Pathogens | TLR7 protein | Cytokines | Dendritic cells | Septicemia | Complications | Pattern recognition | Patients | TLR9 protein | CD4 antigen | Medicine | Studies | Immunosuppression | Monocytes | Injury prevention | Hospitals | Lymphocytes B | Cell number | Antigen-presenting cells | γ-Interferon | Interleukin 10 | Rehabilitation | Molecular biology | Viral infections
Journal Article