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toll-like receptors (289) 289
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tlr9 (132) 132
expression (131) 131
innate immunity (123) 123
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cytokines (111) 111
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research (102) 102
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health aspects (93) 93
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research article (90) 90
cell biology (88) 88
genetic aspects (88) 88
cpg islands (87) 87
deoxyribonucleic acid--dna (85) 85
recognition (80) 80
analysis (79) 79
toll-like receptor 9 (79) 79
gene expression (78) 78
immune response (77) 77
dendritic cells - immunology (75) 75
cancer (74) 74
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mice, knockout (73) 73
biochemistry & molecular biology (71) 71
toll-like receptor (70) 70
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article (68) 68
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multidisciplinary sciences (66) 66
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immunity, innate (58) 58
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oligodeoxynucleotides (56) 56
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Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 03/2014, Volume 34, Issue 3, pp. 516 - 525
Journal Article
Breast Cancer Research and Treatment, ISSN 0167-6806, 4/2012, Volume 132, Issue 2, pp. 411 - 419
Journal Article
Journal Article
Oncotarget, ISSN 1949-2553, 2015, Volume 6, Issue 26, pp. 22564 - 22574
Toll-like receptors (TLRs) play an important role in tumorigenesis and progress of prostate cancer. However, the function and mechanism of Toll-like receptor-9... 
TLR9 | Prostate cancer | Migration | Invasion | SURVIVAL | CELLS | ACTIVATION | RECOGNITION | CELLULAR INVASION | KAPPA-B | CELL BIOLOGY | prostate cancer | IN-VITRO | invasion | INFLAMMATION | migration | RESISTANCE | EXPRESSION
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2015, Volume 10, Issue 9, p. e0134209
Background Dysfunctional innate responses of alveolar macrophages to nontypeable Haemophilus influenzae, Moraxella catarrhalis and Streptococcus pneumoniae... 
OBSTRUCTIVE PULMONARY-DISEASE | NONTYPABLE HAEMOPHILUS-INFLUENZAE | GENE | AIRWAY BACTERIAL LOAD | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | SUSCEPTIBILITY | EXACERBATIONS | NF-KAPPA-B | ASSOCIATION | SINGLE-NUCLEOTIDE POLYMORPHISMS | Interleukin-8 - biosynthesis | Gene Frequency | Humans | Toll-Like Receptor 9 - genetics | Male | Pulmonary Disease, Chronic Obstructive - physiopathology | Immunity, Innate | Case-Control Studies | Alleles | Female | Polymorphism, Single Nucleotide | Macrophages, Alveolar - metabolism | Pulmonary Disease, Chronic Obstructive - metabolism | Respiratory Function Tests | Pulmonary Disease, Chronic Obstructive - immunology | Macrophages, Alveolar - immunology | Amino Acid Substitution | Pulmonary Disease, Chronic Obstructive - genetics | Pneumonia | Lung diseases, Obstructive | Care and treatment | Bacterial pneumonia | Genetic aspects | Single nucleotide polymorphisms | Research | Diagnosis | Macrophages | Risk factors | Haplotypes | Veterans | Critical care | Single-nucleotide polymorphism | Inflammatory diseases | Proteins | Toll-like receptors | Bacteria | Chronic obstructive pulmonary disease | Alveoli | Interleukin 8 | Deoxyribonucleic acid--DNA | Immune system | Lung diseases | TLR4 protein | Morbidity | TLR9 protein | Asthma | Crohns disease | Polymerase chain reaction | Medicine | Studies | Signaling | Hypotheses | Infectious diseases | Sleep | X rays | Respiratory diseases | TLR2 protein | Obstructive lung disease | Ligands | Genetic testing | Smoking | Polymorphism | Deoxyribonucleic acid | DNA
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2013, Volume 8, Issue 12, p. e82571
The toll-like receptor-9 (TLR9) agonist cytosine phosphate guanine (CpG), activates hepatic stellate cells (HSCs) and mediates fibrosis. We investigated the... 
RESPONSES | ACTIVATION | HEPATIC STELLATE CELLS | NK CELLS | MULTIDISCIPLINARY SCIENCES | DISEASE | TLR9 | TOLL-LIKE-RECEPTOR-9 | SENESCENCE | ACCUMULATION | MODULATION | Cell Communication - immunology | Liver Cirrhosis - immunology | Adjuvants, Immunologic - pharmacology | CD8-Positive T-Lymphocytes - pathology | Killer Cells, Natural | Toll-Like Receptor 9 - genetics | Adoptive Transfer | Cell Communication - genetics | Carbon Tetrachloride Poisoning - pathology | Liver Cirrhosis - chemically induced | Mice, Knockout | Toll-Like Receptor 9 - immunology | Animals | Hepatic Stellate Cells - immunology | Cell Communication - drug effects | Carbon Tetrachloride Poisoning - immunology | Liver Cirrhosis - pathology | Carbon Tetrachloride Poisoning - genetics | Mice | CD8-Positive T-Lymphocytes - immunology | Oligodeoxyribonucleotides - pharmacology | Liver Cirrhosis - genetics | Hepatic Stellate Cells - pathology | Phosphates | Killer cells | Pyrimidines | Inflammation | Liver diseases | Cell proliferation | Senescence | CD8 antigen | Liver | Carbon tetrachloride | Activation | Adoptive transfer | Guanine | Hepatitis | Cell activation | Lymphocytes | Rodents | Hepatology | Gastroenterology | Toll-like receptors | Cytosine | Natural killer cells | Drug dosages | Deoxyribonucleic acid--DNA | CpG islands | Stellate cells | Cytokines | CCL4 protein | TLR9 protein | Medicine | Serum levels | Hepatocytes | Fibrosis | Gene therapy | Laboratory animals | Apoptosis | Peritoneum | Deoxyribonucleic acid | DNA
Journal Article
Digestive Diseases and Sciences, ISSN 0163-2116, 11/2016, Volume 61, Issue 11, pp. 3246 - 3254
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2014, Volume 9, Issue 3, p. e92748
Purpose: Activation of Toll like receptors (TLRs) signaling has been implicated in promoting malignant cell invasion and metastatic potential. Previously we... 
MATRIX METALLOPROTEINASES | SITE | SIGNALING PATHWAYS | INVASION | METASTASIS | MULTIDISCIPLINARY SCIENCES | SUPPRESSES | NF-KAPPA-B | CANCER | INNATE IMMUNITY | Gene Expression | Signal Transduction | Matrix Metalloproteinase 2 - metabolism | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - metabolism | Humans | Toll-Like Receptor 9 - genetics | Mouth Neoplasms - metabolism | Enzyme Activation - drug effects | Transcription Factor AP-1 - metabolism | Cell Movement - drug effects | Matrix Metalloproteinase 2 - genetics | Cell Line, Tumor | Oligodeoxyribonucleotides - pharmacology | Toll-Like Receptor 9 - metabolism | Mouth Neoplasms - genetics | Medical research | Squamous cell carcinoma | Prognosis | Analysis | Medicine, Experimental | Metastasis | Health aspects | Enzyme-linked immunosorbent assay | Transcription factors | Oral cancer | Laboratories | Oligonucleotides | Oncology | Activation | Assaying | Cancer therapies | Metastases | Cell adhesion & migration | Proteins | Ethics | Receptors | Cell activation | Transfection | Gelatin | Toll-like receptors | Pretreatment | Deoxyribonucleic acid--DNA | CpG islands | Immune system | Binding | Wound healing | Secretion | siRNA | Oral squamous cell carcinoma | TLR9 protein | Gelatinase A | Medicine | Studies | Signaling | Molecular modelling | Medical prognosis | Healing | Cell migration | Cancer | Deoxyribonucleic acid | DNA
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2013, Volume 8, Issue 3, p. e58444
Inflammation induced by infectious and noninfectious triggers in the kidney may lead to end stage renal disease (ESRD). Toll-like receptor 9 (TLR-9) a receptor... 
MORTALITY | GLOMERULAR-FILTRATION-RATE | GENE | NUTRITIONAL-STATUS | HUMAN TLR9 | MULTIDISCIPLINARY SCIENCES | TOLL-LIKE-RECEPTOR-9 | CPG | CHRONIC KIDNEY-DISEASE | INTERLEUKIN-6 | PROSPECTIVE COHORT | Haplotypes | Promoter Regions, Genetic | Genetic Predisposition to Disease | Humans | Middle Aged | Toll-Like Receptor 9 - genetics | Male | Inflammation | Case-Control Studies | Disease Progression | Kidney Failure, Chronic - metabolism | Polymorphism, Genetic | Kidney Failure, Chronic - genetics | Interleukin-6 - blood | Alleles | HEK293 Cells | Polymerase Chain Reaction | Female | Leukocytes, Mononuclear - cytology | Transcription, Genetic | Aged | Interleukin-6 - metabolism | Medical research | Chronic kidney failure | Interleukins | Genes | Medicine, Experimental | Development and progression | Genetic aspects | Disease susceptibility | Risk factors | Enzyme-linked immunosorbent assay | Infection control | Health care | End-stage renal disease | Nephrology | Transcription | Hemodialysis | Interleukin | Association analysis | Gene polymorphism | Population genetics | Interleukin 6 | Proteins | Toll-like receptors | Public health | Deoxyribonucleic acid--DNA | CpG islands | Immune system | Lupus | Cytokines | Mortality | Health risks | Real time | Disease control | Patients | TLR9 protein | Polymerase chain reaction | Medicine | Hospitals | Lymphomas | Diabetes | Kidney diseases | Polymorphism | Kidney transplantation | Deoxyribonucleic acid | DNA
Journal Article
Journal Article