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International immunopharmacology, ISSN 1567-5769, 2013, Volume 17, Issue 3, pp. 638 - 650
.... Neutrophils express a large number of cell surface receptors for the recognition of pathogen invasion and the inflammatory environment... 
Signaling | Receptors | Inflammation | Kinases | Neutrophils | ACTIVATED PROTEIN-KINASE | COLONY-STIMULATING FACTOR | LEUKOCYTE ADHESION DEFICIENCY | IMMUNOLOGY | SRC-FAMILY KINASES | FORMYL PEPTIDE RECEPTORS | HIGH-AFFINITY RECEPTOR | NOD-LIKE RECEPTORS | BETA-GAMMA-SUBUNIT | TOLL-LIKE RECEPTORS | PHARMACOLOGY & PHARMACY | NF-KAPPA-B | Signal Transduction - immunology | Animals | Receptors, Cell Surface - immunology | Humans | Neutrophils - immunology | Selectins - immunology | Mycoses | Lectins | Fc receptors | Integrins | FcR, Fc-receptor | GPI, glycosylphosphatidylinositol anchor | CLEC, C-type lectin | OSCAR, osteoclast-associated receptor | PKB, protein kinase B | DAG, diacyl-glycerol | Tyk2, tyrosine protein kinase 2 | VCAM-1, vascular cell adhesion molecule 1 | ICAM-1, intercellular adhesion molecule 1 | FADD, Fas-associated protein with death domain | IκB, inhibitor of NF-κB | GM-CSF, granulocyte | MyD88, myeloid differentiation protein 88 | TNF, tumor necrosis factor | LTβ, lymphotoxin β | TRADD, TNFR1-associated death domain protein | Abl, Abelson leukemia proto-oncogene | SLP-76, SH2 domain-containing leukocyte protein of 76 kDa | CALDAG-GEFI, calcium and DAG-regulated guanine nucleotide exchange factor I | IL, interleukin | Src, Rous sarcoma virus proto-oncogene | IRF, IFN regulatory factor | RIG, retinoic acid-inducible gene | PLC, phospholipase C | TCR, T-cell receptor | IKK, IκB kinase | ITAM, immunoreceptor tyrosine-based activation motif | CARD, caspase activation and recruitment domain | IP3, inositol-tris-phosphate | CHO, Chinese hamster ovary cells | MKK, MAP kinase kinase | fMLP, formly-Met-Leu-Phe | TRAF, TNF receptor-associated factor | MIP, macrophage inflammatory protein | Rac, Ras-related C3 botulinum toxin substrate | monocyte colony-stimulating factor | PIP3, phosphatidylinositol-3-phosphate | VLA-4, very late antigen 4 (α4β1 integrin) | PAF, platelet activating factor | STAT, signal transducer and activator of transcription | TAK, TGFβ-activated kinase 1 | Mac-1, macrophage antigen 1 (αMβ2 integrin) | FcRγ, Fc-receptor γ-chain | Asc, apoptosis-associated speck-like protein containing a CARD | cIAP, cellular inhibitor of apoptosis | BCR, B-cell receptor | Fgr, Gardner–Rasheed feline sarcoma proto-oncogene | VASP, vasodilator-stimulated phosphoprotein | Hck, hematopoietic cell kinase | TGFβ, transforming growth factor β | Rap, Ras-related protein | SHP-1, SH2 domain-containing protein tyrosine phosphatase 1 | Syk, spleen tyrosine kinase | GPCR, G protein-coupled receptor | G-CSF, granulocyte colony-stimulating factor | TREM, triggering receptor expressed on myeloid cells | DISC, death-inducing signaling complex | MDL-1, myeloid DAP12-associating lectin 1 | C3G, Crk SH3 domain-binding guanine nucleotide exchange factor (RapGEF1) | NF-κB, nuclear factor κB | ERM, ezrin-radixin-moesin | Epac1, exchange protein activated by cyclic AMP 1 | LTB4, leukotriene B4 | Mcl, macrophage C-type lectin | SAP130, Sin3A-associated protein of 130 kDa | SH2, Src-homology 2 domain | MAP kinase, mitogen-activated protein kinase | PSGL-1, P-selectin glycoprotein ligand | PI3K, phoshoinositide-3-kinase | ADAP, adhesion and degranulation promoting adapter protein (Fyb, SLAP-130) | NLRP3, NOD-like receptor family, pyrin domain containing 3 | MDA5, melanoma differentiation-associated protein 5 | TLR, Toll-like receptor | GRK, GPCR kinase | LAD, leukocyte adhesion deficiency | MAPKAP-kinase, MAP kinase-associated protein kinase | ZAP-70, ζ-chain-associated protein of 70 kDa | TRAIL, TNF-related apoptosis-inducing ligand | JNK, c-Jun N-terminal kinase | LFA-1, lymphocyte function-associated receptor 1 (αLβ2 integrin) | ROS, reactive oxygen species | RIP3, receptor-interacting serine-threonine protein kinase 3 | DAP12, DNAX activating protein 12 | IFN, interferon | PIR, paired immunoglobulin-like receptor | PKC, protein kinase C | PAK, p21-activated kinase | ESL-1, E-selectin ligand 1 | GAP, GTPase activating protein | ERK, extracellular signal-regulated kinase | SOCS, suppressor of cytokine signaling | JAK, Janus kinase | RANK, receptor activator of NF-κB | IRAK, IL-1 receptor-associated kinase | NOD, nucleotide-binding oligomerization domain containing protein | CEACAM3, carcinoembryonic antigen-related cell adhesion molecule 3 (CD66b)
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2011, Volume 108, Issue 50, pp. 20054 - 20059
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2015, Volume 137, Issue 6, pp. 1841 - 1851.e2
Journal Article
Journal Article
The Journal of immunology (1950), ISSN 1550-6606, 2017, Volume 199, Issue 4, pp. 1405 - 1417
Age-related alterations in immunity have been linked to increased incidence of infections and decreased responses to vaccines in the aging population. Human... 
ACTIVATION | REACTIVE OXYGEN | BIOINFORMATICS | STIMULATION | INFLUENZA | INFECTION | IMMUNOLOGY | Interferons - biosynthesis | Humans | Middle Aged | Male | Gene Expression Profiling | Monocytes - immunology | Interferons - immunology | Lipopolysaccharide Receptors - analysis | Young Adult | Receptors, Pattern Recognition - metabolism | Toll-Like Receptor 8 - immunology | Aging - immunology | Receptors, IgG - analysis | Toll-Like Receptor 7 - immunology | Aged, 80 and over | Receptors, Pattern Recognition - agonists | Toll-Like Receptor 4 - agonists | Adult | Female | Transcription, Genetic | Monocytes - classification | Monocytes - physiology | Cytokines - genetics | Cytokines - immunology | Toll-Like Receptor 8 - agonists | Toll-Like Receptor 7 - agonists | Toll-Like Receptor 7 - metabolism | GPI-Linked Proteins - analysis | Toll-Like Receptor 4 - immunology | Immunity, Innate | Toll-Like Receptor 4 - metabolism | Receptors, Pattern Recognition - genetics | Aged | Cytokines - biosynthesis | Toll-Like Receptor 8 - metabolism | Transcription | CX3CR1 protein | Infections | Vaccines | CD14 antigen | Immunity | Impact analysis | Receptors | Biological effects | Peripheral blood | Toll-like receptors | CCL20 protein | Aging | Immune system | Antigen presentation | Immunization | Immune response | TLR7 protein | Pattern recognition | TLR4 protein | IL-1β | Biological activity | Signaling | Monocytes | CD16 antigen | γ-Interferon | Interferon | Adults | Retinoic acid | Alternations
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 09/2007, Volume 282, Issue 36, pp. 26014 - 26025
.... The total fraction of Mycobacterium bovis BCG LM was shown both to induce macrophage activation and pro-inflammatory cytokines through Toll-like receptor 2 (TLR2... 
BACILLUS-CALMETTE-GUERIN | C-TYPE LECTIN | DENDRITIC CELLS | MULTIACYLATED FORMS | SURFACTANT PROTEIN-A | NITRIC-OXIDE SYNTHASE | DC-SIGN | BIOCHEMISTRY & MOLECULAR BIOLOGY | SELECTIVE RECOGNITION | MYO-INOSITOL ANCHOR | 2-DEFICIENT MICE | Mannose-Binding Lectins - metabolism | Mycobacterium bovis - immunology | Toll-Like Receptor 2 - agonists | Membrane Glycoproteins - metabolism | Humans | Lectins, C-Type - immunology | Mycobacterium tuberculosis - immunology | Lipopolysaccharides - metabolism | Cell Adhesion Molecules - immunology | Lipopolysaccharides - immunology | Lectins, C-Type - metabolism | Signal Transduction - immunology | Inflammation - metabolism | Macrophages - secretion | Toll-Like Receptor 1 - agonists | Myeloid Differentiation Factor 88 - immunology | Tumor Necrosis Factor-alpha - immunology | Toll-Like Receptor 4 - agonists | Interleukin-12 Subunit p40 - immunology | Membrane Glycoproteins - immunology | Macrophages - immunology | Acylation | Cell Line | Nitric Oxide - immunology | Immunity, Innate - drug effects | Macrophage Activation - immunology | Receptors, Interleukin-1 - immunology | Tumor Necrosis Factor-alpha - secretion | Receptors, Cell Surface - metabolism | Inflammation - immunology | Toll-Like Receptor 4 - immunology | Toll-Like Receptor 2 - metabolism | Cell Adhesion Molecules - metabolism | Receptors, Cell Surface - immunology | Toll-Like Receptor 4 - metabolism | Mice, Knockout | Receptors, Interleukin-1 - metabolism | Nitric Oxide - secretion | Animals | Mannose-Binding Lectins - immunology | Signal Transduction - drug effects | Lipopolysaccharides - pharmacology | Toll-Like Receptor 2 - immunology | Mice | Toll-Like Receptor 1 - immunology | Macrophage Activation - drug effects | Myeloid Differentiation Factor 88 - metabolism | Toll-Like Receptor 1 | Toll-Like Receptor 2 | Toll-Like Receptor 4 | Cell Adhesion Molecules | Receptors, Cell Surface | Macrophages | Lipopolysaccharides | Life Sciences | Immunology | Membrane Glycoproteins | Mannose-Binding Lectins | Mycobacterium bovis | Signal Transduction | Lectins, C-Type | Inflammation | Myeloid Differentiation Factor 88 | Nitric Oxide | Tumor Necrosis Factor-alpha | Immunity, Natural | Macrophage Activation | Mycobacterium tuberculosis | Receptors, Interleukin-1 | Interleukin-12 Subunit p40
Journal Article
Journal of Virology, ISSN 0022-538X, 2015, Volume 89, Issue 17, pp. 8880 - 8896
.... Several entry and/or adhesion factors, including DC-SIGN, AXL, Tyro3, and, to a lesser extent, TIM-1, permitted ZIKV entry, with a major role for the TAM receptor... 
ACTIVATION | DENGUE-VIRUS | ENTRY | VIROLOGY | MOSQUITOS | WEST-NILE-VIRUS | MACHINERY | HEPARAN-SULFATE | AUTOPHAGY | RECEPTORS | I INTERFERON | Keratinocytes - virology | Membrane Glycoproteins - metabolism | Dendritic Cells - immunology | Humans | Flaviviridae - physiology | Virus Internalization | Interferon-Induced Helicase, IFIH1 | Lectins, C-Type - metabolism | Phagosomes - immunology | RNA Interference | Vero Cells | Myxovirus Resistance Proteins - biosynthesis | DEAD Box Protein 58 | Toll-Like Receptor 3 - immunology | Receptor Protein-Tyrosine Kinases - metabolism | Toll-Like Receptor 3 - metabolism | Cell Adhesion Molecules - metabolism | RNA, Small Interfering | Receptors, Cell Surface - genetics | Cell Adhesion Molecules - genetics | Ubiquitins - biosynthesis | Interferon-beta - immunology | Receptors, Virus - metabolism | Cercopithecus aethiops | Receptors, Virus - genetics | Lectins, C-Type - genetics | Insect Vectors - virology | Autophagy - immunology | Aedes - virology | Flaviviridae - immunology | Toll-Like Receptor 7 - immunology | HEK293 Cells | Toll-Like Receptor 3 - genetics | DEAD-box RNA Helicases - metabolism | Dendritic Cells - virology | Skin - virology | Flaviviridae Infections - immunology | Skin - immunology | Fibroblasts - virology | Proto-Oncogene Proteins - metabolism | Cells, Cultured | Interferon-beta - biosynthesis | Receptors, Cell Surface - metabolism | Proto-Oncogene Proteins - genetics | Hepatitis A Virus Cellular Receptor 1 | Flaviviridae Infections - virology | Membrane Glycoproteins - genetics | DEAD-box RNA Helicases - genetics | Animals | Receptor Protein-Tyrosine Kinases - genetics | Virus Replication | Cytokines - biosynthesis | Life Sciences | Microbiology and Parasitology | Cellular Biology | Biochemistry, Molecular Biology | Virology
Journal Article