International Journal of Pharmaceutics, ISSN 0378-5173, 11/2016, Volume 514, Issue 1, pp. 52 - 57
Topical formulations aim to target the skin for a variety of cosmetic, protective or therapeutic needs. Despite the use of creams and ointments over the...
Supersaturation | Crystallisation | Skin | Penetration | Advanced topical formulation | PROPYLENE-GLYCOL | HUMAN STRATUM-CORNEUM | DRUG-DELIVERY | SKIN IN-VITRO | METHYL NICOTINATE | SUPERSATURATED SOLUTIONS | PHARMACOLOGY & PHARMACY | PERCUTANEOUS-ABSORPTION | VEHICLE COMPOSITION | MEMBRANE-TRANSPORT | Chemistry, Pharmaceutical - methods | Ointments - chemistry | Cosmetics - chemistry | Biological Availability | Skin Absorption | Administration, Cutaneous | Animals | Cosmetics - administration & dosage | Pharmaceutical Preparations - chemistry | Ointments - administration & dosage | Diffusion | Pharmaceutical Preparations - administration & dosage | Skin - drug effects
Supersaturation | Crystallisation | Skin | Penetration | Advanced topical formulation | PROPYLENE-GLYCOL | HUMAN STRATUM-CORNEUM | DRUG-DELIVERY | SKIN IN-VITRO | METHYL NICOTINATE | SUPERSATURATED SOLUTIONS | PHARMACOLOGY & PHARMACY | PERCUTANEOUS-ABSORPTION | VEHICLE COMPOSITION | MEMBRANE-TRANSPORT | Chemistry, Pharmaceutical - methods | Ointments - chemistry | Cosmetics - chemistry | Biological Availability | Skin Absorption | Administration, Cutaneous | Animals | Cosmetics - administration & dosage | Pharmaceutical Preparations - chemistry | Ointments - administration & dosage | Diffusion | Pharmaceutical Preparations - administration & dosage | Skin - drug effects
Journal Article
Pain Medicine, ISSN 1526-2375, 12/2013, Volume 14, Issue 1, pp. S35 - S39
Objective This article reviews topical nonsteroidal anti‐inflammatory drug (NSAID) formulations available in the United States, including advantages and...
Osteoarthritis | Topical | Nonsteroidal Anti‐Inflammatory Drug | Nonsteroidal Anti-Inflammatory Drug | MANAGEMENT | SAFETY | RANDOMIZED CONTROLLED-TRIAL | DELIVERY | GEL | WARFARIN ANTICOAGULATION | MEDICINE, GENERAL & INTERNAL | METHYLSALICYLATE OINTMENT | PAIN | ANESTHESIOLOGY | KNEE OSTEOARTHRITIS | Anti-Inflammatory Agents, Non-Steroidal - adverse effects | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Humans | Anti-Inflammatory Agents, Non-Steroidal - administration & dosage | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Evidence-Based Medicine | Administration, Topical | Chemistry, Pharmaceutical | Drug Delivery Systems | Drug therapy | Nonsteroidal anti-inflammatory drugs
Osteoarthritis | Topical | Nonsteroidal Anti‐Inflammatory Drug | Nonsteroidal Anti-Inflammatory Drug | MANAGEMENT | SAFETY | RANDOMIZED CONTROLLED-TRIAL | DELIVERY | GEL | WARFARIN ANTICOAGULATION | MEDICINE, GENERAL & INTERNAL | METHYLSALICYLATE OINTMENT | PAIN | ANESTHESIOLOGY | KNEE OSTEOARTHRITIS | Anti-Inflammatory Agents, Non-Steroidal - adverse effects | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Humans | Anti-Inflammatory Agents, Non-Steroidal - administration & dosage | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Evidence-Based Medicine | Administration, Topical | Chemistry, Pharmaceutical | Drug Delivery Systems | Drug therapy | Nonsteroidal anti-inflammatory drugs
Journal Article
International Journal of Pharmaceutics, ISSN 0378-5173, 08/2015, Volume 492, Issue 1-2, pp. 161 - 168
Recently there has been a growth of interest in the novel skin care formulations containing active ingredients such as low molecular weight peptides. In this...
Topical formulations | Low molecular peptides | Release rate | Einstein–Smoluchowski equation | Diffusion test | Einstein-Smoluchowski equation | DESIGN | BASES | EMULSION | STABILITY | MEMBRANE | SURFACE | PHARMACOLOGY & PHARMACY | LAB(R) EXPERT ANALYSIS | Particle Size | Viscosity | Emulsions | Drug Stability | Skin Care | Drug Liberation | Cosmetics | Oligopeptides - chemistry | Chemistry, Pharmaceutical | Hydrogels - chemistry | Hydrogen-Ion Concentration | Skin | Toiletries industry | Skin care products
Topical formulations | Low molecular peptides | Release rate | Einstein–Smoluchowski equation | Diffusion test | Einstein-Smoluchowski equation | DESIGN | BASES | EMULSION | STABILITY | MEMBRANE | SURFACE | PHARMACOLOGY & PHARMACY | LAB(R) EXPERT ANALYSIS | Particle Size | Viscosity | Emulsions | Drug Stability | Skin Care | Drug Liberation | Cosmetics | Oligopeptides - chemistry | Chemistry, Pharmaceutical | Hydrogels - chemistry | Hydrogen-Ion Concentration | Skin | Toiletries industry | Skin care products
Journal Article
International Journal of Pharmaceutics, ISSN 0378-5173, 2007, Volume 340, Issue 1, pp. 198 - 206
Enhancement of the chemical stability of ascorbyl palmitate (AP) after incorporation into nanostructured lipid carriers (NLC) has been reported. However, the...
Nanostructured lipid carriers | NLC | Antioxidant | Ascorbyl palmitate | Chemical stability | chemical stability | antioxidant | NANOPARTICLES SLN | TOPICAL MICROEMULSIONS | ascorbyl palmitate | PHARMACOLOGY & PHARMACY | nanostructured lipid carriers | DELIVERY | Temperature | Antioxidants - chemistry | Ascorbic Acid - analogs & derivatives | Colloids | Drug Stability | Nanostructures | Chemistry, Pharmaceutical | Drug Carriers | Particle Size | Lipids - chemistry | Technology, Pharmaceutical | Nitrogen - chemistry | Time Factors | X-Ray Diffraction | Ascorbic Acid - chemistry | Drug Compounding | Calorimetry, Differential Scanning | Surface-Active Agents - chemistry | Spectrum Analysis | Antioxidants | Analysis | Nanotechnology
Nanostructured lipid carriers | NLC | Antioxidant | Ascorbyl palmitate | Chemical stability | chemical stability | antioxidant | NANOPARTICLES SLN | TOPICAL MICROEMULSIONS | ascorbyl palmitate | PHARMACOLOGY & PHARMACY | nanostructured lipid carriers | DELIVERY | Temperature | Antioxidants - chemistry | Ascorbic Acid - analogs & derivatives | Colloids | Drug Stability | Nanostructures | Chemistry, Pharmaceutical | Drug Carriers | Particle Size | Lipids - chemistry | Technology, Pharmaceutical | Nitrogen - chemistry | Time Factors | X-Ray Diffraction | Ascorbic Acid - chemistry | Drug Compounding | Calorimetry, Differential Scanning | Surface-Active Agents - chemistry | Spectrum Analysis | Antioxidants | Analysis | Nanotechnology
Journal Article
Nature Reviews Drug Discovery, ISSN 1474-1776, 2014, Volume 13, Issue 9, pp. 655 - 672
The formulation and delivery of biopharmaceutical drugs, such as monoclonal antibodies and recombinant proteins, poses substantial challenges owing to their...
HALF-LIFE | SYSTEMIC DELIVERY | HUMAN GROWTH-HORMONE | CONCENTRATED MONOCLONAL-ANTIBODY | DRUG-DELIVERY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | FUSION PROTEIN | PHARMACOLOGY & PHARMACY | ORAL DELIVERY | IN-VIVO EVALUATION | SUSTAINED-RELEASE | TOPICAL DELIVERY | Animals | Chemistry, Pharmaceutical - methods | Biopharmaceutics - methods | Humans | Biopharmaceutics - trends | Drug Delivery Systems - trends | Drug Delivery Systems - methods | Chemistry, Pharmaceutical - trends | Drugs | Pharmaceutical research | Drug delivery systems | Innovations | Research | Biopharmaceutics | Vehicles
HALF-LIFE | SYSTEMIC DELIVERY | HUMAN GROWTH-HORMONE | CONCENTRATED MONOCLONAL-ANTIBODY | DRUG-DELIVERY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | FUSION PROTEIN | PHARMACOLOGY & PHARMACY | ORAL DELIVERY | IN-VIVO EVALUATION | SUSTAINED-RELEASE | TOPICAL DELIVERY | Animals | Chemistry, Pharmaceutical - methods | Biopharmaceutics - methods | Humans | Biopharmaceutics - trends | Drug Delivery Systems - trends | Drug Delivery Systems - methods | Chemistry, Pharmaceutical - trends | Drugs | Pharmaceutical research | Drug delivery systems | Innovations | Research | Biopharmaceutics | Vehicles
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 11/2016, Volume 242, pp. 126 - 140
Strong barrier properties of often limits the efficiency of drug delivery through skin. Several strategies were tried to improve permeation of drug through...
Liposome | Skin | Penetration mechanism | Nanosystem | Permeation | HUMAN STRATUM-CORNEUM | DRUG-DELIVERY | TRADITIONAL DIFFUSION CELLS | SKIN IN-VITRO | VITRO PERCUTANEOUS PERMEATION | CHEMISTRY, MULTIDISCIPLINARY | NONIONIC SURFACTANT VESICLES | HAIR-FOLLICLES | ATR-FTIR SPECTROSCOPY | TEMOPORFIN-LOADED INVASOMES | PHARMACOLOGY & PHARMACY | TOPICAL DELIVERY | Technology, Pharmaceutical - trends | Animals | History, 21st Century | Skin - metabolism | History, 20th Century | Humans | Skin Absorption | Administration, Cutaneous | Drug Delivery Systems - trends | Liposomes | Chemistry, Pharmaceutical - trends | Drug Carriers - chemistry | Dermatologic agents | Dermatology | Analysis | Transdermal medication | Formulae, receipts, prescriptions | Proteins | Molecular biology
Liposome | Skin | Penetration mechanism | Nanosystem | Permeation | HUMAN STRATUM-CORNEUM | DRUG-DELIVERY | TRADITIONAL DIFFUSION CELLS | SKIN IN-VITRO | VITRO PERCUTANEOUS PERMEATION | CHEMISTRY, MULTIDISCIPLINARY | NONIONIC SURFACTANT VESICLES | HAIR-FOLLICLES | ATR-FTIR SPECTROSCOPY | TEMOPORFIN-LOADED INVASOMES | PHARMACOLOGY & PHARMACY | TOPICAL DELIVERY | Technology, Pharmaceutical - trends | Animals | History, 21st Century | Skin - metabolism | History, 20th Century | Humans | Skin Absorption | Administration, Cutaneous | Drug Delivery Systems - trends | Liposomes | Chemistry, Pharmaceutical - trends | Drug Carriers - chemistry | Dermatologic agents | Dermatology | Analysis | Transdermal medication | Formulae, receipts, prescriptions | Proteins | Molecular biology
Journal Article
Parasites and Vectors, ISSN 1756-3305, 2012, Volume 5, Issue 1, pp. 79 - 79
Background: Two studies evaluating the efficacy of an imidacloprid/flumethrin collar (Seresto (R), Bayer Animal Health, IVP), a deltamethrin collar (Scalibor...
Dinotefuran | Ticks | Amitraz | Methoprene | Efficacy | Imidacloprid | Fleas | Deltamethrin | Flumethrin | Collar | Fipronil | Spot-on | COLLINS | MOSQUITOS | PERMETHRIN | COMBINATION | INFESTATIONS | STILES | PYRIPROXYFEN | PARASITOLOGY | Tick Infestations - veterinary | Male | Flea Infestations - prevention & control | Insecticides - administration & dosage | Flea Infestations - veterinary | Tick Infestations - prevention & control | Animals | Ctenocephalides | Dogs | Female | Administration, Topical | Delayed-Action Preparations | Rhipicephalus sanguineus | Dog Diseases - parasitology | Dog Diseases - prevention & control | Arachnids | Design | Organisms | Parasites | Parasitic diseases
Dinotefuran | Ticks | Amitraz | Methoprene | Efficacy | Imidacloprid | Fleas | Deltamethrin | Flumethrin | Collar | Fipronil | Spot-on | COLLINS | MOSQUITOS | PERMETHRIN | COMBINATION | INFESTATIONS | STILES | PYRIPROXYFEN | PARASITOLOGY | Tick Infestations - veterinary | Male | Flea Infestations - prevention & control | Insecticides - administration & dosage | Flea Infestations - veterinary | Tick Infestations - prevention & control | Animals | Ctenocephalides | Dogs | Female | Administration, Topical | Delayed-Action Preparations | Rhipicephalus sanguineus | Dog Diseases - parasitology | Dog Diseases - prevention & control | Arachnids | Design | Organisms | Parasites | Parasitic diseases
Journal Article
Journal of nanoscience and nanotechnology, ISSN 1533-4880, 06/2018, Volume 18, Issue 6, pp. 4428 - 4438
This work describes the development of poly-epsilon-caprolactone nanocapsules (PCL-NC) and solid lipid nanoparticles (SLN) aiming delivery for articaine (ATC),...
PHYSICS, CONDENSED MATTER | PHYSICS, APPLIED | EFFICACY | DRUG-DELIVERY | MATERIALS SCIENCE, MULTIDISCIPLINARY | LOCAL-ANESTHETIC ARTICAINE | NANOSCIENCE & NANOTECHNOLOGY | ALGINATE/CHITOSAN NANOPARTICLES | RELEASE | Solid Lipid Nanoparticles | CHEMISTRY, MULTIDISCIPLINARY | Semisolid Formulation | GEL | Topical Anesthetics | SLN | LIDOCAINE | PCL Nanocapsules | IN-VITRO ASSAYS | Articaine | Hydrogel | SKIN PENETRATION | Nanoparticles | Formulations | Thixotropy | Pseudoplasticity | Stability | Hydrogels | Polydispersity | Skin preparations | Semisolids | In vitro methods and tests | Viability | Rheological properties
PHYSICS, CONDENSED MATTER | PHYSICS, APPLIED | EFFICACY | DRUG-DELIVERY | MATERIALS SCIENCE, MULTIDISCIPLINARY | LOCAL-ANESTHETIC ARTICAINE | NANOSCIENCE & NANOTECHNOLOGY | ALGINATE/CHITOSAN NANOPARTICLES | RELEASE | Solid Lipid Nanoparticles | CHEMISTRY, MULTIDISCIPLINARY | Semisolid Formulation | GEL | Topical Anesthetics | SLN | LIDOCAINE | PCL Nanocapsules | IN-VITRO ASSAYS | Articaine | Hydrogel | SKIN PENETRATION | Nanoparticles | Formulations | Thixotropy | Pseudoplasticity | Stability | Hydrogels | Polydispersity | Skin preparations | Semisolids | In vitro methods and tests | Viability | Rheological properties
Journal Article
Polymers for Advanced Technologies, ISSN 1042-7147, 06/2018, Volume 29, Issue 6, pp. 1815 - 1825
Ricinoleic acid (RA) has potential to promote wound healing because of its analgesic and anti‐inflammatory properties. This study investigates the synthesis...
chitosan hydrogel | wound healing | ricinoleic acid | liposomes | topical application | TASTE MASKING | HYDROGELS | POLYMER SCIENCE | DRUG-DELIVERY | CONTROLLED-RELEASE | CHITOSAN MICROSPHERES | CASTOR-OIL | IN-VIVO | SUSTAINED-RELEASE | Care and treatment | Wound healing | Lecithin | Analysis | Nuclear magnetic resonance spectroscopy | Cyclodextrins | Skin | Chemical properties | Wounds and injuries | Formulations | Hydrogels | Ricinoleic acid | Gelation | Mechanical properties | Epidermis | Moisture content | Morphology | Chitosan | Liposomes
chitosan hydrogel | wound healing | ricinoleic acid | liposomes | topical application | TASTE MASKING | HYDROGELS | POLYMER SCIENCE | DRUG-DELIVERY | CONTROLLED-RELEASE | CHITOSAN MICROSPHERES | CASTOR-OIL | IN-VIVO | SUSTAINED-RELEASE | Care and treatment | Wound healing | Lecithin | Analysis | Nuclear magnetic resonance spectroscopy | Cyclodextrins | Skin | Chemical properties | Wounds and injuries | Formulations | Hydrogels | Ricinoleic acid | Gelation | Mechanical properties | Epidermis | Moisture content | Morphology | Chitosan | Liposomes
Journal Article
Skin Research and Technology, ISSN 0909-752X, 02/2016, Volume 22, Issue 1, pp. 46 - 54
Background The tactile perception is essential for all types of topical formulations (cosmetic, pharmaceutical, medical device) and the possibility to predict...
tactile perception | finger/tactile friction | moisturizers | hydration | skin friction | topical formulations | Moisturizers | Topical formulations | Hydration | Skin friction | Tactile perception | Finger/tactile friction | DRUG-DELIVERY | STRATUM-CORNEUM | OLEIC-ACID | TRANSEPIDERMAL WATER-LOSS | CUBIC PHASE GELS | COSMETIC PRODUCTS | DERMATOLOGY | IN-VITRO | PERCEIVED SKIN FEEL | SENSORY EVALUATION | Emollients - administration & dosage | Humans | Middle Aged | Touch - drug effects | Male | Skin Physiological Phenomena | Fingers - physiology | Surface Properties | Skin Cream - administration & dosage | Adult | Female | Touch - physiology | Friction - drug effects | Product development | Toiletries industry | Sensors | Structure | Analysis | Crystals | Friction | Phase transitions | Skin care products | Naturvetenskap | Natural Sciences | Fysikalisk kemi | Physical Chemistry | Kemi | Chemical Sciences
tactile perception | finger/tactile friction | moisturizers | hydration | skin friction | topical formulations | Moisturizers | Topical formulations | Hydration | Skin friction | Tactile perception | Finger/tactile friction | DRUG-DELIVERY | STRATUM-CORNEUM | OLEIC-ACID | TRANSEPIDERMAL WATER-LOSS | CUBIC PHASE GELS | COSMETIC PRODUCTS | DERMATOLOGY | IN-VITRO | PERCEIVED SKIN FEEL | SENSORY EVALUATION | Emollients - administration & dosage | Humans | Middle Aged | Touch - drug effects | Male | Skin Physiological Phenomena | Fingers - physiology | Surface Properties | Skin Cream - administration & dosage | Adult | Female | Touch - physiology | Friction - drug effects | Product development | Toiletries industry | Sensors | Structure | Analysis | Crystals | Friction | Phase transitions | Skin care products | Naturvetenskap | Natural Sciences | Fysikalisk kemi | Physical Chemistry | Kemi | Chemical Sciences
Journal Article
Current Pharmaceutical Design, ISSN 1381-6128, 10/2017, Volume 23, Issue 35, pp. 5327 - 5335
In the last decades, gene therapy has become a novel therapeutic strategy for cancer treatment, including immunologic and molecular approaches. Among molecular...
Liposomes | Gene therapy | Cationic nanocarriers | Niosomes | Cancer | ETHANOL INJECTION METHOD | CATIONIC LIPOSOMES | cationic nanocarriers | TRANSFECTION EFFICIENCY | niosomes | gene therapy | NANO-NIOSOMES | VIRAL VECTORS | SMALL INTERFERING RNA | PLASMID DNA | SURFACTANT VESICLES NIOSOMES | PHARMACOLOGY & PHARMACY | cancer |
Liposomes | Gene therapy | Cationic nanocarriers | Niosomes | Cancer | ETHANOL INJECTION METHOD | CATIONIC LIPOSOMES | cationic nanocarriers | TRANSFECTION EFFICIENCY | niosomes | gene therapy | NANO-NIOSOMES | VIRAL VECTORS | SMALL INTERFERING RNA | PLASMID DNA | SURFACTANT VESICLES NIOSOMES | PHARMACOLOGY & PHARMACY | cancer |