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Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 10/2017, Volume 27, Issue 20, pp. 4687 - 4693
Journal Article
Science (American Association for the Advancement of Science), ISSN 1095-9203, 2011, Volume 333, Issue 6041, pp. 459 - 462
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International journal of molecular sciences, ISSN 1422-0067, 2018, Volume 19, Issue 9, p. 2765
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Journal Article
Current medicinal chemistry, ISSN 0929-8673, 12/2010, Volume 17, Issue 35, pp. 4270 - 4290
Journal Article
Journal Article
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Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 05/2018, Volume 26, Issue 9, pp. 2354 - 2364
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The Journal of Clinical Pharmacology, ISSN 0091-2700, 12/2018, Volume 58, Issue 12, pp. 1557 - 1565
Journal Article
Current Medicinal Chemistry, ISSN 0929-8673, 05/2016, Volume 23, Issue 6, pp. 520 - 577
In the late 1980s, reports emerged describing experimental antibacterial quinolones having significant potency against eukaryotic Type II topoisomerases (topo... 
Topo IV | Quinolone | Paul Ehrlich | Etoposide | G quadruplex | Selectivity | Antibacterial | Cytotoxic | Doxorubicin | Topo II | Vosaroxin | Gyrase | Antitumor | Topoisomerase | Quarfloxin | Fluoroquinolone | Magic bullet | Anticancer | selectivity | vosaroxin | antitumor | topo IV | antibacterial | CELL-CYCLE ARREST | RESISTANT STAPHYLOCOCCUS-AUREUS | anticancer | 7-SUBSTITUTED 1,4-DIHYDRO-4-OXO-1-(2-THIAZOLYL)-1,8-NAPHTHYRIDINE-3-CARBOXYLIC ACIDS | gyrase | EXPLOITING MECHANISTIC DIFFERENCES | quarfloxin | PHARMACOLOGY & PHARMACY | doxorubicin | topo II | cytotoxic | TELOMERIC G-QUADRUPLEXES | CHEMISTRY, MEDICINAL | fluoroquinolone | BIOCHEMISTRY & MOLECULAR BIOLOGY | SIDE-EFFECT RELATIONSHIPS | ACUTE MYELOID-LEUKEMIA | magic bullet | MAMMALIAN TOPOISOMERASE-II | topoisomerase | etoposide | ANTIBODY-BASED THERAPIES | DRUG-INTERACTION DOMAINS | Neoplasms - metabolism | DNA Topoisomerases, Type II - metabolism | Antibiotics, Antineoplastic - pharmacology | Humans | Models, Molecular | Drug Discovery - methods | Quinolones - pharmacology | Topoisomerase II Inhibitors - pharmacology | Topoisomerase II Inhibitors - therapeutic use | Neoplasms - drug therapy | Anti-Bacterial Agents - therapeutic use | Animals | Quinolones - chemistry | Antibiotics, Antineoplastic - chemistry | Antibiotics, Antineoplastic - therapeutic use | Signal Transduction - drug effects | Topoisomerase II Inhibitors - chemistry | Anti-Bacterial Agents - chemistry | Quinolones - therapeutic use | Anti-Bacterial Agents - pharmacology
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