X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (217) 217
torc1 (217) 217
cell biology (115) 115
biochemistry & molecular biology (90) 90
humans (90) 90
rapamycin (89) 89
animals (83) 83
signal transduction (78) 78
yeast (72) 72
saccharomyces-cerevisiae (69) 69
saccharomyces cerevisiae proteins - metabolism (64) 64
transcription factors - metabolism (57) 57
phosphorylation (54) 54
saccharomyces cerevisiae - metabolism (54) 54
autophagy (51) 51
tor serine-threonine kinases - metabolism (51) 51
article (49) 49
mechanistic target of rapamycin complex 1 (48) 48
proteins (48) 48
mtor (44) 44
saccharomyces cerevisiae - genetics (42) 42
multiprotein complexes - metabolism (40) 40
pathway (38) 38
transcription factors - genetics (38) 38
complex (37) 37
saccharomyces cerevisiae proteins - genetics (37) 37
activation (36) 36
metabolism (36) 36
rag gtpases (35) 35
amino acids (34) 34
cell-growth (33) 33
mammalian target (33) 33
growth (32) 32
saccharomyces cerevisiae (31) 31
transcription (30) 30
kinases (29) 29
microbiology (29) 29
physiological aspects (29) 29
cancer (28) 28
sirolimus - pharmacology (28) 28
torc2 (28) 28
ego complex (27) 27
gene-expression (27) 27
mice (27) 27
protein (27) 27
analysis (26) 26
biology (26) 26
gene expression regulation, fungal (26) 26
genetics & heredity (26) 26
research (26) 26
male (25) 25
protein binding (25) 25
tor (24) 24
female (23) 23
protein-serine-threonine kinases - metabolism (23) 23
oncology (22) 22
transfer-rna synthetase (22) 22
amino acids - metabolism (21) 21
gene expression (21) 21
kinase (21) 21
monomeric gtp-binding proteins - metabolism (21) 21
akt (20) 20
genetic aspects (20) 20
target of rapamycin complex 1 (20) 20
tor protein (20) 20
tor serine-threonine kinases - antagonists & inhibitors (20) 20
budding yeast (19) 19
mechanistic target of rapamycin complex 1 - metabolism (19) 19
mtorc1 (19) 19
mutation (19) 19
nutrients (19) 19
research article (19) 19
biotechnology & applied microbiology (18) 18
controls torc1 (18) 18
signal transduction - physiology (18) 18
signaling (18) 18
hek293 cells (16) 16
life sciences (16) 16
signal transduction - drug effects (16) 16
target (16) 16
biophysics (15) 15
cells (15) 15
models, biological (15) 15
molecular biology (15) 15
protein transport (15) 15
review (15) 15
saccharomyces cerevisiae - drug effects (15) 15
saccharomyces cerevisiae - physiology (15) 15
sch9 (15) 15
starvation (15) 15
aging (14) 14
apoptosis (14) 14
binding (14) 14
expression (14) 14
homeostasis (14) 14
localization (14) 14
mitochondria (14) 14
multidisciplinary sciences (14) 14
signaling pathway (14) 14
cell cycle (13) 13
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Urologic Oncology: Seminars and Original Investigations, ISSN 1078-1439, 09/2019
Journal Article
BMB Reports, ISSN 1976-6696, 2017, Volume 50, Issue 9, pp. 437 - 444
Different types of eukaryotic cells may adopt seemingly distinct modes of directional cell migration. However, several core aspects are regarded common whether... 
B56 | Dictyostelium | TorC2 | TorC1 | PP2A | Akt | Chemotaxis
Journal Article
Annals of Oncology, ISSN 0923-7534, 09/2018, Volume 29, Issue 9, pp. 1918 - 1925
Abstract Background We have previously shown that raised p-S6K levels correlate with resistance to chemotherapy in ovarian cancer. We hypothesised that... 
combination therapy | squamous non-small-cell lung cancer | phase 1 | m-TORC1/m-TORC2 inhibitor | ovarian cancer | MAMMALIAN TARGET | ADVANCED SOLID TUMORS | TRASTUZUMAB | EVEROLIMUS | RISK | 1ST-IN-HUMAN | CHEMOTHERAPY | AZD2014 | ONCOLOGY | PATHWAY | PHASE-I | m-TORC1 | m-TORC2 inhibitor | Original
Journal Article
World Journal of Clinical Oncology, ISSN 2218-4333, 12/2018, Volume 9, Issue 8, pp. 172 - 179
Breast cancer (BC) is the most common cancer in women and second only to lung cancer in terms of mortality. Among the three different BC subtypes, the... 
Hormone receptor positive/Her2-negative breast cancer | Akt | PI3K | TORC1/2 | Everolimus | MTOR | TORC1 | Hormone receptor positive | mTOR | Her2-negative breast cancer
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 2019, Volume 25, Issue 6, pp. 1889 - 1900
Purpose: Over 95% of human anal cancers are etiologically associated with high-risk HPVs, with HPV type 16 (HPV16) the genotype most commonly found. Activating... 
HEAD | MUTAGENESIS | ONCOLOGY | RAS | TORC1/2 INHIBITOR | MLN0128 | PAPILLOMAVIRUS TYPE-16 E7 | ANTITUMOR-ACTIVITY | CANCER | MTOR
Journal Article
Journal of Cell Science, ISSN 0021-9533, 06/2009, Volume 122, Issue 12, pp. 2089 - 2099
Journal Article
Applied and environmental microbiology, ISSN 0099-2240, 01/2019, Volume 85, Issue 1
ABSTRACT Saccharomyces cerevisiae sake yeast strain Kyokai no. 7 (K7) and its relatives carry a homozygous loss-of-function mutation in the RIM15 gene, which... 
Greatwall | Rim15p | TORC1 | PP2AB55δ | Schizosaccharomyces pombe | PP2A | alcoholic fermentation | sake yeast | Cdc55p | Saccharomyces cerevisiae
Journal Article
FEMS yeast research, ISSN 1567-1356, 06/2017, Volume 17, Issue 4
What follows are snapshots of my career in chicken eyes, yeast and Rhodospirillum rubrum, castor beans, Escherichia coli and finally yeast again. In contrast,... 
CENIII | beta-oxidation in glyoxysomes | carboxylase mechanisms | nitrogen catabolite repression | Gln3 | TorC1,Gcn2 control | Gcn2 control | CARBOXYLASE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | TorC1 | MICROBIOLOGY | MYCOLOGY | SACCHAROMYCES-CEREVISIAE | Beans
Journal Article
BBA - General Subjects, ISSN 0304-4165, 03/2019, Volume 1863, Issue 3, pp. 534 - 546
The heat shock proteins Hsp31–34 are members of DJ-1/ThiJ/Pfpl superfamily that includes human DJ-1 (Park7), a protein involved in heritable Parkinsonism.... 
TORC1 | Methylglyoxal | DJ-1/PARK7 | Sfp1 | Hsp31 | Proteasome | BIOCHEMISTRY & MOLECULAR BIOLOGY | CYSTEINE | NETWORKS | AUTOPHAGY | BIOPHYSICS | DATABASE | PROTEIN DJ-1
Journal Article
ISSN 0960-9822, 2017
Extracellular cues regulate cell fate, and this is mainly achieved through the engagement of specific transcriptional programs. The TORC1 and TORC2 complexes... 
nitrogen starvation | TORC1 | TORC2 | B55 | sexual differentiation | S. pombe | PP2A | Gad8
Journal Article
Journal of Cell Biology, ISSN 0021-9525, 08/2018, Volume 217, Issue 8, pp. 2765 - 2776
Folliculin (FLCN) is a tumor suppressor that coordinates cellular responses to changes in amino acid availability via regulation of the Rag guanosine... 
FOLLICULIN | TORC1 | COMPLEX | ACTIVATION | GENE | G-PROTEINS | HOGG-DUBE-SYNDROME | TUMOR-SUPPRESSOR | MTORC1 PATHWAY | DENN-DOMAIN | CELL BIOLOGY
Journal Article
Nucleic acids research, ISSN 0305-1048, 06/2019, Volume 47, Issue 10, pp. 4974 - 4985
Regulation of the efficiency with which an mRNA is translated into proteins represents a key mechanism for controlling gene expression. Such regulation impacts... 
YEAST | TARGET | TORC1 | RESOLUTION VIEW | BIOCHEMISTRY & MOLECULAR BIOLOGY | GENE-EXPRESSION | ABSORPTION | TRANSCRIPTION FACTOR | RIBOSOME BIOGENESIS | CYCLE | MOLECULES | Data Resources and Analyses
Journal Article
ISSN 0923-7534, 2018
Background: We have previously shown that raised p-S6K levels correlate with resistance to chemotherapy in ovarian cancer. We hypothesised that inhibiting... 
combination therapy | squamous non-small cell lung cancer | m-TORC1/m-TORC2 inhibitor | Phase 1 | ovarian cancer
Journal Article
Scientific Reports, ISSN 2045-2322, 03/2017, Volume 7, Issue 1, p. 44257
The Target of Rapamycin (TOR) signalling network plays important roles in aging and disease. The AMP-activated protein kinase (AMPK) and the Gsk3 kinase... 
LIFE-SPAN | TORC1 | INHIBITION | SIGNALING PATHWAY | PHOSPHORYLATION | MULTIDISCIPLINARY SCIENCES | KINASE | AMPK | CELL-GROWTH | WNT | SCHIZOSACCHAROMYCES-POMBE | TOR protein | Gene silencing | Chromatin | 5-Fluorouracil | AMP | DNA damage | Ribosomes | Rapamycin | Cell size | AMP-activated protein kinase | Kinases | DNA repair
Journal Article