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Journal of Biological Chemistry, ISSN 0021-9258, 12/2010, Volume 285, Issue 51, pp. 40050 - 40059
The calcium-regulated phosphatase calcineurin intersects with both calcium and cAMP-mediated signaling pathways in the pancreatic beta-cell. Pharmacologic... 
DIABETES-MELLITUS | GLUCOSE-HOMEOSTASIS | PROTEIN-KINASE-B | GLUCAGON-LIKE PEPTIDE-1 | CYCLIN D1 | KIDNEY-TRANSPLANTATION | COACTIVATOR TORC2 | PRIMARY MECHANISM | BIOCHEMISTRY & MOLECULAR BIOLOGY | IRS-2 EXPRESSION | GENE-EXPRESSION | Pancreatic Islet | Molecular Bases of Disease | Diabetes | Insulin | Calcineurin | Apoptosis
Journal Article
Genetics, ISSN 0016-6731, 09/2018, Volume 210, Issue 1, pp. 155 - 170
Journal Article
The EMBO Journal, ISSN 0261-4189, 07/2008, Volume 27, Issue 14, pp. 1919 - 1931
Protein kinase C (PKC) is involved in a wide array of cellular processes such as cell proliferation, differentiation and apoptosis. Phosphorylation of both... 
mTOR | PKC | TORC2 | Akt | RAPAMYCIN | PROTEIN-KINASE-C | ACTIVATION | AKT/PKB | MECHANISM | BIOCHEMISTRY & MOLECULAR BIOLOGY | PHOSPHOINOSITIDE 3-KINASE | CELL BIOLOGY | INSULIN | RICTOR-MTOR COMPLEX | SUBSTRATE | GROWTH | Cellular biology | Kinases | Signal transduction
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2007, Volume 104, Issue 51, pp. 20314 - 20319
Signal transduction pathways often use a transcriptional component to mediate adaptive cellular responses. Coactivator proteins function prominently in these... 
Transcription factors | Transcriptional regulatory elements | Torcs | RNA | HEK293 cells | Plasmids | Genes | Small interfering RNA | Antibodies | Gene expression regulation | Cell-based screen | Signal transduction | Transcription | Transducer of regulated cAMP response element-binding protein | RNA polymerase II | transducer of regulated cAMP response element-binding protein | DNA-BINDING | TORC2 | PSF | transcription | signal transduction | MULTIDISCIPLINARY SCIENCES | MAMMALIAN-CELLS | NUCLEAR-PROTEIN CBP | CREB | cell-based screen | SENSITIVE COINCIDENCE DETECTOR | TRANSCRIPTIONAL ACTIVATOR | GENE-EXPRESSION | Cell Line | RNA-Binding Proteins - genetics | Octamer Transcription Factors - antagonists & inhibitors | Signal Transduction | Humans | Nuclear Matrix-Associated Proteins - metabolism | Transcription Factors - metabolism | Protein Interaction Mapping - methods | Nuclear Matrix-Associated Proteins - genetics | RNA Interference | Octamer Transcription Factors - genetics | Nuclear Matrix-Associated Proteins - antagonists & inhibitors | Transcription, Genetic | Cyclic AMP - metabolism | Octamer Transcription Factors - metabolism | RNA-Binding Proteins - metabolism | RNA-Binding Proteins - antagonists & inhibitors | Evaluation | Cyclic adenylic acid | Cellular signal transduction | Research | Genetic transcription | Properties | Binding proteins | Human genetics | Biological Sciences | transducer of regulated cAMP response element | binding protein
Journal Article
Journal Article
Trends in Cardiovascular Medicine, ISSN 1050-1738, 2011, Volume 21, Issue 5, pp. 151 - 155
Journal Article