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1. Full Text RANKL cytokine enhances TNF-induced osteoclastogenesis independently of TNF receptor associated factor (TRAF) 6 by degrading TRAF3 in osteoclast precursors
by Yao, Zhenqiang and Lei, Wei and Duan, Rong and Li, Yanyun and Luo, Lu and Boyce, Brendan F
Journal of Biological Chemistry, ISSN 0021-9258, 06/2017, Volume 292, Issue 24, pp. 10169 - 10179
Cytokines, including receptor activator of nuclear factor kappa B ligand (RANKL) and TNF, induce increased osteoclast (OC) formation and bone loss in... 
RHEUMATOID-ARTHRITIS | TUMOR-NECROSIS-FACTOR | GROWTH-FACTOR-BETA | ACTIVATION | TGF-BETA | C-FOS | BIOCHEMISTRY & MOLECULAR BIOLOGY | DEFECTIVE INTERLEUKIN-1 | NF-KAPPA-B | T-CELLS | BONE-RESORPTION | Tumor Necrosis Factor-alpha - metabolism | Bone and Bones - pathology | RANK Ligand - metabolism | Spleen - immunology | Tumor Necrosis Factor-alpha - genetics | Autophagy - drug effects | Tumor Necrosis Factor-alpha - agonists | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Bone and Bones - drug effects | Chloroquine - pharmacology | Proteolysis - drug effects | Osteoclasts - immunology | TNF Receptor-Associated Factor 3 - genetics | Bone and Bones - metabolism | Cell Culture Techniques | TNF Receptor-Associated Factor 6 - genetics | Bone Demineralization, Pathologic - metabolism | Osteoclasts - pathology | Actin Cytoskeleton - metabolism | Osteogenesis - drug effects | Cells, Cultured | TNF Receptor-Associated Factor 3 - metabolism | Spleen - cytology | Actin Cytoskeleton - immunology | Osteoclasts - metabolism | Mice, Knockout | RANK Ligand - genetics | Animals | Spleen - metabolism | Protein Stability - drug effects | TNF Receptor-Associated Factor 6 - metabolism | Bone Demineralization, Pathologic - pathology | Mice | Actin Cytoskeleton - pathology | Bone and Bones - immunology | Osteoclasts - drug effects | Bone Demineralization, Pathologic - immunology | RANKL | TGF-β | bone | osteoclast | TNF | TNF receptor-associated factor (TRAF) | Cell Biology
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2. Full Text Dynamic arginine methylation of tumor necrosis factor (TNF) receptor-associated factor 6 regulates toll-like receptor signaling
by Tikhanovich, Irina and Kuravi, Sudhakiranmayi and Artigues, Antonio and Villa, Maria T and Dorko, Kenneth and Nawabi, Atta and Roberts, Benjamin and Weinman, Steven A
Journal of Biological Chemistry, ISSN 0021-9258, 09/2015, Volume 290, Issue 36, pp. 22236 - 22249
Arginine methylation is a common post-translational modification, but its role in regulating protein function is poorly understood. This study demonstrates... 
SURVIVAL | RESPONSES | CELLS | ACTIVATION | PRMT1 | NEGATIVE REGULATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | JMJD6 | A20 | Interleukin-1 Receptor-Associated Kinases - metabolism | Interleukin-1 Receptor-Associated Kinases - genetics | Humans | Male | NF-kappa B - metabolism | RNA Interference | Protein-Arginine N-Methyltransferases - genetics | TNF Receptor-Associated Factor 6 - genetics | Toll-Like Receptors - metabolism | Repressor Proteins - metabolism | Cell Line | Signal Transduction | Mice, Inbred C57BL | Cells, Cultured | Ubiquitin-Protein Ligases - metabolism | Repressor Proteins - genetics | Jumonji Domain-Containing Histone Demethylases - genetics | Blotting, Western | Protein-Arginine N-Methyltransferases - metabolism | Animals | NF-kappa B - genetics | TNF Receptor-Associated Factor 6 - metabolism | Cell Line, Tumor | Ligands | Kinetics | Methylation | Ubiquitin-Protein Ligases - genetics | Jumonji Domain-Containing Histone Demethylases - metabolism | Arginine - metabolism | Index Medicus | Immunology | hepatocyte | innate immunity | arginine methylation | macrophage | toll-like receptor (TLR) | post-translational modification | Jumonji domain-containing protein 6 | TNF receptor associated factor (TRAF) | endotoxin | protein arginine methyltransferase
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3. Full Text Identification and characterization of a TNF receptor-associated factor in Dugesia japonica
by Hu, Wenjing and Wu, Weiwei and Sun, Shimin and Liu, Dongwu and Liu, Zuojun and Liu, Xi and Liu, Baohua and Li, Ao and Gao, Lili and Deng, Hongkuan and Zhao, Bosheng and Pang, Qiuxiang
Gene, ISSN 0378-1119, 01/2019, Volume 681, pp. 52 - 61
The tumor necrosis factor (TNF) superfamily consists of a wide variety of inflammatory cytokine, including cell-bound and secreted proteins. These TNFs... 
Dugesia japonica | TRAF | Localization | Expression pattern | Immunity | NECROSIS-FACTOR RECEPTOR | ACTIVATION | TRAF2 | INDUCTION | DROSOPHILA | CELL-DEATH | PLANARIANS | INTERACTS | GENETICS & HEREDITY | ANIMAL-MODEL | NF-KAPPA-B | Fluorescence | Tumor necrosis factor | Mitogens | Protein binding
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4. Full Text Tumor necrosis factor (TNF) receptor-associated factor (TRAF)-interacting protein (TRIP) negatively regulates the TRAF2 ubiquitin-dependent pathway by suppressing the TRAF2-sphingosine 1-phosphate (S1P) interaction
by Park, Eui-Soon and Choi, Seunga and Shin, Bongjin and Yu, Jungeun and Yu, Jiyeon and Hwang, Jung-Me and Yun, Hyeongseok and Chung, Young-Ho and Choi, Jong-Soon and Choi, Yongwon and Rho, Jaerang
Journal of Biological Chemistry, ISSN 0021-9258, 04/2015, Volume 290, Issue 15, pp. 9660 - 9673
The signaling pathway downstream of TNF receptor (TNFR) is involved in the induction of a wide range of cellular processes, including cell proliferation,... 
GENE | BIOCHEMISTRY & MOLECULAR BIOLOGY | ALPHA | DEGRADATION | IKK ACTIVATION | DIFFERENTIATION | NF-KAPPA-B | SIGNALING COMPLEXES | EXPRESSION | DROSOPHILA | LIGASE | Tumor Necrosis Factor-alpha - metabolism | Lysophospholipids - metabolism | Humans | TNF Receptor-Associated Factor 2 - genetics | Tumor Necrosis Factor-alpha - genetics | Ubiquitin - metabolism | Immunoblotting | NF-kappa B - metabolism | Ubiquitination | RNA Interference | HEK293 Cells | Lysine - metabolism | Sphingosine - metabolism | Cytokines - genetics | Tumor Necrosis Factor Receptor-Associated Peptides and Proteins - genetics | Gene Expression | Cytokines - metabolism | TNF Receptor-Associated Factor 2 - metabolism | Binding Sites - genetics | Reverse Transcriptase Polymerase Chain Reaction | Tumor Necrosis Factor Receptor-Associated Peptides and Proteins - metabolism | Tumor Necrosis Factor-alpha - pharmacology | Lysine - genetics | Sphingosine - analogs & derivatives | Signal Transduction - drug effects | Protein Binding | HeLa Cells | NF-κB | TNFR | TRAF-interacting Protein | Signal Transduction | Sphingosine 1-Phosphate (S1P) | TNF Receptor-associated Factor (TRAF) | Tumor Necrosis Factor (TNF) | Inflammation | Ubiquitylation (Ubiquitination)
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5. Full Text Roles for TNF-receptor associated factor 3 (TRAF3) in lymphocyte functions
by Yi, Zuoan and Lin, Wai Wai and Stunz, Laura L and Bishop, Gail A
Cytokine and Growth Factor Reviews, ISSN 1359-6101, 2014, Volume 25, Issue 2, pp. 147 - 156
Abstract TRAF3 is an adapter protein that serves and regulates the functions of several types of receptors, located both inside the cell and at the plasma... 
Advanced Basic Science | B lymphocyte | Signal transduction | Lymphocyte activation | T lymphocyte | TRAF | BIOCHEMISTRY & MOLECULAR BIOLOGY | HUMAN CD40 RECEPTOR | ONCOPROTEIN TIO | CELL BIOLOGY | HERPESVIRUS ENTRY MEDIATOR | NECROSIS-FACTOR FAMILY | REGULATORY T-CELLS | TOLL-LIKE RECEPTORS | IMMUNE REGULATION | SURVIVAL SIGNALS | NF-KAPPA-B | EPSTEIN-BARR-VIRUS | Humans | Toll-Like Receptors - immunology | NF-kappa B - immunology | Signal Transduction - immunology | Animals | B-Lymphocytes - immunology | TNF Receptor-Associated Factor 3 - genetics | TNF Receptor-Associated Factor 3 - immunology | Receptors, Antigen, T-Cell - immunology | Receptors, Cytokine - immunology | T-Lymphocytes - immunology | Mice | Receptors, Tumor Necrosis Factor - immunology | T cells | Tumor necrosis factor | lymphocyte activation | signal transduction
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6. Full Text Genomic and Functional Uniqueness of the TNF Receptor-Associated Factor Gene Family in Amphioxus, the Basal Chordate
by Yuan, Shaochun and Liu, Tong and Huang, Shengfeng and Wu, Tao and Huang, Ling and Liu, Huiling and Tao, Xin and Yang, Manyi and Wu, Kui and Yu, Yanhong and Dong, Meiling and Xu, Anlong
The Journal of Immunology, ISSN 0022-1767, 10/2009, Volume 183, Issue 7, pp. 4560 - 4568
The TNF-associated factor (TRAF) family, the crucial adaptor group in innate immune signaling, increased to 24 in amphioxus, the oldest lineage of the... 
ANTIVIRAL RESPONSE | IMMUNE-RESPONSE | REPERTOIRE | ACTIVATION | FACTOR TRAF | RING FINGER | IMMUNOLOGY | NF-KAPPA-B | TERMINAL KINASE | DROSOPHILA | NONREDUNDANT | Chordata - genetics | TNF Receptor-Associated Factor 6 - physiology | Drosophila melanogaster - immunology | TNF Receptor-Associated Factor 4 - physiology | Humans | TNF Receptor-Associated Factor 2 - genetics | TNF Receptor-Associated Factor 3 - physiology | Molecular Sequence Data | NF-kappa B - metabolism | TNF Receptor-Associated Factor 2 - physiology | TNF Receptor-Associated Factor 3 - chemistry | Drosophila melanogaster - genetics | TNF Receptor-Associated Factor 4 - chemistry | Signal Transduction - immunology | TNF Receptor-Associated Factor 3 - genetics | Tumor Necrosis Factor Receptor-Associated Peptides and Proteins - physiology | TNF Receptor-Associated Factor 2 - chemistry | Proteomics - methods | TNF Receptor-Associated Factor 6 - genetics | Tumor Necrosis Factor Receptor-Associated Peptides and Proteins - genetics | Multigene Family - genetics | TNF Receptor-Associated Factor 4 - genetics | Cell Line | Chordata - physiology | Signal Transduction - genetics | Animals | Drosophila melanogaster - chemistry | TNF Receptor-Associated Factor 6 - chemistry | HeLa Cells | Multigene Family - immunology
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7. Full Text Tumor Necrosis Factor (TNF)-Mediated Kinase Cascades: Bifurcation of Nuclear Factor-κ B and c-Jun N-Terminal Kinase (JNK/SAPK) Pathways at TNF Receptor-Associated Factor 2
by Ho Yeong Song and Catherine H. Regnier and Carsten J. Kirschning and David V. Goeddel and Mike Rothe
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/1997, Volume 94, Issue 18, pp. 9792 - 9796
TNF-induced activation of the transcription factor NF-κ B and the c-jun N-terminal kinase (JNK/SAPK) requires TNF receptor-associated factor 2 (TRAF2). The... 
Proteins | Transfection | Plasmids | DNA | Reporter genes | Tumor necrosis factors | Cellular immunity | Epitopes | Family members | Polyclonal antibodies | Extracellular signal-regulated kinase kinase 1 | Mitogen-activated protein kinase | Nuclear factor-κB-inducing kinase | TNF receptor- associated factor 6 | Interleukin 1 | TNF receptor-associated factor 6 | CYTOPLASMIC DOMAIN | FACTOR FAMILY | nuclear factor-kappa B-inducing kinase | ACTIVATION | CD40 | CONTAINS 2 | TRAF | SIGNAL-TRANSDUCING PROTEINS | MULTIDISCIPLINARY SCIENCES | FACTOR-ALPHA | CELL-DEATH | mitogen-activated protein kinase | interleukin 1 | K RO MULTIDISCIPLINARY SCIENCES | BINDING-SITES | extracellular signal-regulated kinase kinase 1 | Biological Sciences | nuclear factor-κB-inducing kinase
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8. Full Text Inducible Tumor Necrosis Factor (TNF) receptor-associated factor-1 expression couples the canonical to the non-canonical NF-κB pathway in TNF stimulation
by Choudhary, Sanjeev and Kalita, Mridul and Fang, Ling and Patel, Kershaw V and Tian, Bing and Zhao, Yingxin and Edeh, Chukwudi B and Brasier, Allan R
Journal of Biological Chemistry, ISSN 0021-9258, 05/2013, Volume 288, Issue 20, pp. 14612 - 14623
The NF-kappa B transcription factor mediates the inflammatory response through distinct (canonical and non-canonical) signaling pathways. The mechanisms... 
KINASE-ALPHA | COMPLEX-FORMATION | ACTIVATION | PROTEIN | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | GENE-EXPRESSION | TRAF2 | IDENTIFICATION | LYMPHOTOXIN | CIAP2 | Models, Theoretical | Signal Transduction | Humans | Lung Neoplasms - metabolism | TNF Receptor-Associated Factor 1 - metabolism | Gene Expression Regulation, Neoplastic | Gene Expression Profiling | Subcellular Fractions - metabolism | NF-kappa B p52 Subunit - metabolism | Microscopy, Confocal | Mass Spectrometry | Cell Line, Tumor | Protein-Serine-Threonine Kinases - metabolism | RNA, Small Interfering - metabolism | NIK | Mathematical Modeling | TRAF | NF-κB Transcription Factor | Tumor Necrosis Factor (TNF) | Inflammation
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9. Full Text Regulation of Interleukin-6 Receptor Signaling by TNF Receptor-Associated Factor 2 and 5 During Differentiation of Inflammatory CD4(+) T Cells
by Nagashima, H and Ishii, N and So, T
FRONTIERS IN IMMUNOLOGY, ISSN 1664-3224, 08/2018, Volume 9, p. 1986
There is growing evidence that tumor necrosis factor (TNF) receptor-associated factors (TRAFs) bind to unconventional membrane-bound receptors in many cell... 
FACTOR FAMILY | NECROSIS-FACTOR RECEPTOR | MEMBERS | PROTEIN | RECOGNITION | TRAF2 | IMMUNOLOGY | IL-6 | autoimmunity | inflammation | STRUCTURAL BASIS | TRAF5 | T(H)17 | TRAF FAMILY | GENES | EXPRESSION | LYMPHOCYTES | Research | T cells | Cell differentiation | Tumor necrosis factor | Interleukin-6 | TH17
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10. Full Text Molecular cloning, expression and functional characterization of tumor necrosis factor (TNF) receptor-associated factor (TRAF)-interacting protein (TRIP) in grass carp, Ctenopharyngodon idella
by Lu, R.-H and Chang, Z.-G and Sun, J and Yang, F and Nie, G.-X and Ji, H
Fish and Shellfish Immunology, ISSN 1050-4648, 10/2016, Volume 57, pp. 406 - 412
TRIP (Tumor Necrosis Factor (TNF) Receptor-Associated Factor (TRAF)-Interacting Protein), a member of the TNF superfamily, plays a crucial role in the... 
TRIP (tumor necrosis factor (TNF) receptor-associated factor (TRAF)-Interacting protein | Immune defense | Ctenopharyngodon idella | Inflammation | Tissue distribution | PATHWAYS | ACTIVATION | TRIP (tumor necrosis factor (TNF) receptor associated factor (TRAF)-Interacting protein | NONSPECIFIC IMMUNE-RESPONSES | UBIQUITIN | IMMUNOLOGY | FISHERIES | MARINE & FRESHWATER BIOLOGY | DISEASE | FISH | SUPERFAMILY | VETERINARY SCIENCES | NUTRITION | SIGNALING COMPLEXES | TRAF-INTERACTING PROTEIN | Dietary Carbohydrates - administration & dosage | Carps - metabolism | Fish Proteins - chemistry | Humans | RNA, Messenger - genetics | DNA, Complementary - genetics | Gene Expression Regulation | Fish Proteins - metabolism | Lipids - administration & dosage | Phylogeny | RNA, Messenger - metabolism | Carps - immunology | Tumor Necrosis Factor Receptor-Associated Peptides and Proteins - metabolism | Tumor Necrosis Factor Receptor-Associated Peptides and Proteins - chemistry | Fish Proteins - genetics | Animals | Animal Feed - analysis | Cloning, Molecular | HEK293 Cells | Carps - genetics | DNA, Complementary - metabolism | Tumor Necrosis Factor Receptor-Associated Peptides and Proteins - genetics | Diet - veterinary | Sequence Analysis, Protein - veterinary
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11. Full Text A Critical Role for TNF Receptor-Associated Factor 1 and Bim Down-Regulation in CD8 Memory T Cell Survival
by Laurent Sabbagh and Cathy C. Srokowski and Gayle Pulle and Laura M. Snell and Bradley J. Sedgmen and Yuanqing Liu and Erdyni N. Tsitsikov and Tania H. Watts
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2006, Volume 103, Issue 49, pp. 18703 - 18708
The mechanisms that allow the maintenance of immunological memory remain incompletely defined. Here we report that tumor necrosis factor receptor... 
T lymphocytes | Protein isoforms | Recovered memory | Memory | Small interfering RNA | Orthomyxoviridae | Cultured cells | Infections | Family members | Adoptive transfer | Influenza virus | Knockout/transgenic mice | Bcl-2 family | ACTIVATION | INDUCED APOPTOSIS | MULTIDISCIPLINARY SCIENCES | TRAF1 | FAMILY-MEMBER BIM | 4-1BB LIGAND | knockout/transgenic mice | FACTOR (TRAF)-1 | IN-VIVO | influenza virus | NF-KAPPA-B | ANTIGEN | CD8-Positive T-Lymphocytes - cytology | Cell Survival - genetics | TNF Receptor-Associated Factor 1 - physiology | Proto-Oncogene Proteins - biosynthesis | Signal Transduction - immunology | Bcl-2-Like Protein 11 | Apoptosis Regulatory Proteins - genetics | TNF Receptor-Associated Factor 1 - deficiency | Immunologic Memory - genetics | Apoptosis Regulatory Proteins - biosynthesis | Proto-Oncogene Proteins - antagonists & inhibitors | Membrane Proteins - genetics | Mice, Inbred C57BL | TNF Receptor-Associated Factor 1 - genetics | Mice, Transgenic | Proto-Oncogene Proteins - genetics | Signal Transduction - genetics | Cell Survival - immunology | Mice, Knockout | Membrane Proteins - biosynthesis | Animals | Membrane Proteins - antagonists & inhibitors | Apoptosis Regulatory Proteins - antagonists & inhibitors | Mice | CD8-Positive T-Lymphocytes - immunology | Influenza viruses | Research | Tumor necrosis factor | Health aspects | CD8 lymphocytes | knockout | Biological Sciences | transgenic mice
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12. Full Text TNF Receptor-Associated Factor 6 Is an Essential Mediator of CD40-Activated Proinflammatory Pathways in Monocytes and Macrophages
by Mukundan, Lata and Bishop, Gail A and Head, Kimberly Z and Zhang, Lihua and Wahl, Larry M and Suttles, Jill
The Journal of Immunology, ISSN 0022-1767, 01/2005, Volume 174, Issue 2, pp. 1081 - 1090
The interaction between CD40 and its ligand, CD154, has been shown to play a role in the onset and maintenance of inflammatory disease. Contributing to this... 
SIGNAL-TRANSDUCTION | INTERLEUKIN-1 | ACTIVATED PROTEIN-KINASE | HUMAN DENDRITIC CELLS | FACTORS TRAFS | CD40-CD40 LIGAND | ENDOTHELIAL-CELLS | CD40 LIGAND | IMMUNOLOGY | NF-KAPPA-B | MOLECULAR-MECHANISMS | TNF Receptor-Associated Factor 6 - physiology | Humans | Neoplasm Proteins - physiology | TNF Receptor-Associated Factor 2 - genetics | Cell Membrane Permeability | Molecular Sequence Data | Monocytes - metabolism | NF-kappa B - metabolism | Monocytes - immunology | Signal Transduction - immunology | CD40 Antigens - metabolism | TNF Receptor-Associated Factor 3 - genetics | Inflammation Mediators - metabolism | CD40 Antigens - genetics | src-Family Kinases - physiology | TNF Receptor-Associated Factor 6 - genetics | Binding Sites | Inflammation Mediators - physiology | Macrophages - immunology | Protein-Serine-Threonine Kinases - metabolism | Amino Acid Sequence | CD40 Antigens - physiology | Cells, Cultured | TNF Receptor-Associated Factor 2 - metabolism | TNF Receptor-Associated Factor 3 - metabolism | TNF Receptor-Associated Factor 5 - metabolism | I-kappa B Kinase | Macrophages - enzymology | Monocytes - enzymology | Macrophages - metabolism | TNF Receptor-Associated Factor 5 - genetics | Mitogen-Activated Protein Kinase 3 - metabolism | TNF Receptor-Associated Factor 6 - metabolism | Cytokines - antagonists & inhibitors | Enzyme Activation | Intracellular Signaling Peptides and Proteins - physiology | Cell Line, Transformed | Cytokines - biosynthesis | Mitogen-Activated Protein Kinase 1 - metabolism
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13. Full Text Tumor Necrosis Factor (TNF) receptor-associated factor 7 is required for TNFα-induced Jun NH2-terminal kinase activation and promotes cell death by regulating polyubiquitination and lysosomal degradation of c-FLIP protein
by Scudiero, Ivan and Zotti, Tiziana and Ferravante, Angela and Vessichelli, Mariangela and Reale, Carla and Masone, Maria C and Leonardi, Antonio and Vito, Pasquale and Stilo, Romania
Journal of Biological Chemistry, ISSN 0021-9258, 02/2012, Volume 287, Issue 8, pp. 6053 - 6061
The pro-inflammatory cytokine tumor necrosis factor (TNF) alpha signals both cell survival and death. The biological outcome of TNF alpha treatment is... 
CASPASE-8 ACTIVATION | INHIBITORY PROTEIN | JNK | BIOCHEMISTRY & MOLECULAR BIOLOGY | THERAPEUTIC TARGET | DOWN-REGULATION | RESISTANCE | CHRONIC LYMPHOCYTIC-LEUKEMIA | TRAIL-INDUCED APOPTOSIS | MEDIATED APOPTOSIS | NF-KAPPA-B | Lysosomes - drug effects | Polyubiquitin - metabolism | RNA, Small Interfering - genetics | Jurkat Cells | Humans | JNK Mitogen-Activated Protein Kinases - metabolism | Enzyme Activation - drug effects | Gene Knockdown Techniques | Tumor Necrosis Factor Receptor-Associated Peptides and Proteins - metabolism | Gene Expression Regulation - drug effects | Proteolysis - drug effects | Tumor Necrosis Factor Receptor-Associated Peptides and Proteins - deficiency | Tumor Necrosis Factor-alpha - pharmacology | Lysosomes - metabolism | Ubiquitination - drug effects | HEK293 Cells | Cell Death - drug effects | HeLa Cells | CASP8 and FADD-Like Apoptosis Regulating Protein - metabolism | Tumor Necrosis Factor Receptor-Associated Peptides and Proteins - genetics | TRAF7 | Ubiquitination | Signal Transduction | TRAF | Tumor necrosis factor (TNF) | Lysosomes | Jun NH2-terminal kinase (JNK) | Apoptosis
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14. Full Text Cooperation between TNF Receptor-Associated Factors 1 and 2 in CD40 Signaling
by Xie, Ping and Hostager, Bruce S and Munroe, Melissa E and Moore, Carissa R and Bishop, Gail A
The Journal of Immunology, ISSN 0022-1767, 05/2006, Volume 176, Issue 9, pp. 5388 - 5400
TNFR-associated factor 1 (TRAF1) is unique among the TRAF family, lacking most zinc-binding features, and showing marked up-regulation following activation... 
MOLECULAR MECHANISMS | TARGETED DISRUPTION | FACTOR (TRAF)-1 | INDUCED APOPTOSIS | CELL ANTIGEN RECEPTOR | TRANSFORMING PROTEIN | IMMUNOLOGY | LATENT MEMBRANE-PROTEIN | NF-KAPPA-B | EPSTEIN-BARR-VIRUS | LYMPHOCYTE-ACTIVATION | Cell Line | Immunoglobulins - immunology | Signal Transduction | Membrane Microdomains - metabolism | TNF Receptor-Associated Factor 1 - metabolism | TNF Receptor-Associated Factor 2 - genetics | Gene Expression Regulation | TNF Receptor-Associated Factor 1 - genetics | TNF Receptor-Associated Factor 2 - metabolism | JNK Mitogen-Activated Protein Kinases - metabolism | NF-kappa B - metabolism | Mice, Knockout | Animals | B-Lymphocytes - immunology | CD40 Antigens - metabolism | Mice | Enzyme Activation | Immunoglobulins - biosynthesis | TNF Receptor-Associated Factor 1 - deficiency | B-Lymphocytes - metabolism | TNF Receptor-Associated Factor 2 - deficiency
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15. Full Text TNF Receptor-Associated Factor (TRAF) Signaling Network in CD4+ T-Lymphocytes
by So, Takanori and Nagashima, Hiroyuki and Ishii, Naoto
The Tohoku Journal of Experimental Medicine, ISSN 0040-8727, 2015, Volume 236, Issue 2, pp. 139 - 154
CD4+ T helper cells (TH cells), such as TH1, TH2, TH17, TFH, and Treg cells, play critical roles in host defense against infection and in the pathogenesis of... 
TNFR | T-cell biology | CD4+ T cells | signalosome | TRAF | CD4 | Signalosome | T cells | TRANSCRIPTION FACTORS | CYTOPLASMIC DOMAIN | MEDICINE, RESEARCH & EXPERIMENTAL | COSTIMULATORY RECEPTOR | NEGATIVE REGULATOR | MEDICINE, GENERAL & INTERNAL | FAMILY-MEMBER | TARGETED DISRUPTION | HERPESVIRUS ENTRY MEDIATOR | STRUCTURAL BASIS | DEFECTIVE INTERLEUKIN-1 | CD4(+) T cells | NF-KAPPA-B | Animals | Humans | Signal Transduction - physiology | CD4-Positive T-Lymphocytes - physiology | Cytokines - physiology | Receptors, Antigen, T-Cell - physiology | Receptors, Tumor Necrosis Factor - physiology
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