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International immunopharmacology, ISSN 1567-5769, 11/2013, Volume 17, Issue 3, pp. 638 - 650
Signaling | Receptors | Inflammation | Kinases | Neutrophils | Pharmacology & Pharmacy | Immunology | Life Sciences & Biomedicine | Science & Technology | Signal Transduction - immunology | Animals | Receptors, Cell Surface - immunology | Humans | Neutrophils - immunology | Selectins - immunology | Mycoses | Lectins | Fc receptors | Integrins | Index Medicus | FcR, Fc-receptor | GPI, glycosylphosphatidylinositol anchor | CLEC, C-type lectin | OSCAR, osteoclast-associated receptor | PKB, protein kinase B | DAG, diacyl-glycerol | Tyk2, tyrosine protein kinase 2 | VCAM-1, vascular cell adhesion molecule 1 | ICAM-1, intercellular adhesion molecule 1 | FADD, Fas-associated protein with death domain | IκB, inhibitor of NF-κB | GM-CSF, granulocyte | MyD88, myeloid differentiation protein 88 | TNF, tumor necrosis factor | LTβ, lymphotoxin β | TRADD, TNFR1-associated death domain protein | Abl, Abelson leukemia proto-oncogene | SLP-76, SH2 domain-containing leukocyte protein of 76 kDa | CALDAG-GEFI, calcium and DAG-regulated guanine nucleotide exchange factor I | IL, interleukin | Src, Rous sarcoma virus proto-oncogene | IRF, IFN regulatory factor | RIG, retinoic acid-inducible gene | PLC, phospholipase C | TCR, T-cell receptor | IKK, IκB kinase | ITAM, immunoreceptor tyrosine-based activation motif | CARD, caspase activation and recruitment domain | IP3, inositol-tris-phosphate | CHO, Chinese hamster ovary cells | MKK, MAP kinase kinase | fMLP, formly-Met-Leu-Phe | TRAF, TNF receptor-associated factor | MIP, macrophage inflammatory protein | Rac, Ras-related C3 botulinum toxin substrate | monocyte colony-stimulating factor | PIP3, phosphatidylinositol-3-phosphate | VLA-4, very late antigen 4 (α4β1 integrin) | PAF, platelet activating factor | STAT, signal transducer and activator of transcription | TAK, TGFβ-activated kinase 1 | Mac-1, macrophage antigen 1 (αMβ2 integrin) | FcRγ, Fc-receptor γ-chain | Asc, apoptosis-associated speck-like protein containing a CARD | cIAP, cellular inhibitor of apoptosis | BCR, B-cell receptor | Fgr, Gardner–Rasheed feline sarcoma proto-oncogene | VASP, vasodilator-stimulated phosphoprotein | Hck, hematopoietic cell kinase | TGFβ, transforming growth factor β | Rap, Ras-related protein | SHP-1, SH2 domain-containing protein tyrosine phosphatase 1 | Syk, spleen tyrosine kinase | GPCR, G protein-coupled receptor | G-CSF, granulocyte colony-stimulating factor | TREM, triggering receptor expressed on myeloid cells | DISC, death-inducing signaling complex | MDL-1, myeloid DAP12-associating lectin 1 | C3G, Crk SH3 domain-binding guanine nucleotide exchange factor (RapGEF1) | NF-κB, nuclear factor κB | ERM, ezrin-radixin-moesin | Epac1, exchange protein activated by cyclic AMP 1 | LTB4, leukotriene B4 | Mcl, macrophage C-type lectin | SAP130, Sin3A-associated protein of 130 kDa | SH2, Src-homology 2 domain | MAP kinase, mitogen-activated protein kinase | PSGL-1, P-selectin glycoprotein ligand | PI3K, phoshoinositide-3-kinase | ADAP, adhesion and degranulation promoting adapter protein (Fyb, SLAP-130) | NLRP3, NOD-like receptor family, pyrin domain containing 3 | MDA5, melanoma differentiation-associated protein 5 | TLR, Toll-like receptor | GRK, GPCR kinase | LAD, leukocyte adhesion deficiency | MAPKAP-kinase, MAP kinase-associated protein kinase | ZAP-70, ζ-chain-associated protein of 70 kDa | TRAIL, TNF-related apoptosis-inducing ligand | JNK, c-Jun N-terminal kinase | LFA-1, lymphocyte function-associated receptor 1 (αLβ2 integrin) | ROS, reactive oxygen species | RIP3, receptor-interacting serine-threonine protein kinase 3 | DAP12, DNAX activating protein 12 | IFN, interferon | PIR, paired immunoglobulin-like receptor | PKC, protein kinase C | PAK, p21-activated kinase | ESL-1, E-selectin ligand 1 | GAP, GTPase activating protein | ERK, extracellular signal-regulated kinase | SOCS, suppressor of cytokine signaling | JAK, Janus kinase | RANK, receptor activator of NF-κB | IRAK, IL-1 receptor-associated kinase | NOD, nucleotide-binding oligomerization domain containing protein | CEACAM3, carcinoembryonic antigen-related cell adhesion molecule 3 (CD66b)
Journal Article
FEBS letters, ISSN 0014-5793, 05/2015, Volume 589, Issue 12, pp. 1369 - 1375
Ubiquitin | Tumor necrosis factor-α | Nuclear factor-κB | Apoptosis | receptor-interacting protein | interleukin-1 | TRAF | TRADD | PARP | HOIP | IκB kinase | IκB | NF-κB | transforming growth factor-β-activated kinase 1 | heme-oxidized iron regulatory protein-2 ubiquitin ligase-1 | TAK1 | HOIL-1 | Fas-associated protein with death domain | TNF-related apoptosis-inducing ligand | cIAP | FADD | HOIL-1-interacting protein | TNF receptor-associated factor | Poly (ADP-ribose) polymerase | TNF receptor-associated death domain | TRAIL | IL-1 | IKK | cellular inhibitor of apoptosis | nuclear factor-κB | TNF-α | tumor necrosis factor-α | RIP | inhibitor of κB | Biochemistry & Molecular Biology | Biophysics | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Cysteine Endopeptidases - chemistry | Tumor Necrosis Factor-alpha - metabolism | Apoptosis - drug effects | Humans | Tumor Necrosis Factor-alpha - genetics | Ubiquitin-Protein Ligases - antagonists & inhibitors | Interleukin-1alpha - metabolism | NF-kappa B - metabolism | Baculoviral IAP Repeat-Containing 3 Protein | Intracellular Signaling Peptides and Proteins - metabolism | DNA-Binding Proteins - metabolism | Cysteine Endopeptidases - metabolism | Inhibitor of Apoptosis Proteins - antagonists & inhibitors | Tumor Necrosis Factor alpha-Induced Protein 3 | Inhibitor of Apoptosis Proteins - metabolism | Interleukin-1alpha - genetics | Nuclear Proteins - genetics | Intracellular Signaling Peptides and Proteins - genetics | Recombinant Proteins - metabolism | Cell Line | Cell Survival - drug effects | NF-kappa B - antagonists & inhibitors | Zinc Fingers | Enzyme Inhibitors - pharmacology | Ubiquitin-Protein Ligases - metabolism | Recombinant Proteins - chemistry | Mutant Proteins - metabolism | Nuclear Proteins - metabolism | DNA-Binding Proteins - genetics | Nuclear Proteins - chemistry | DNA-Binding Proteins - chemistry | Animals | Intracellular Signaling Peptides and Proteins - chemistry | Cysteine Endopeptidases - genetics | Mutant Proteins - chemistry | Mice | Amino Acid Substitution | Index Medicus
Journal Article
Seminars in cancer biology, ISSN 1044-579X, 06/2018, Volume 50, pp. 77 - 89
Life Sciences & Biomedicine | Oncology | Science & Technology | DNA Repair - drug effects | Humans | Gene Expression Regulation, Neoplastic | Antineoplastic Agents - therapeutic use | Neoplasms - drug therapy | Cell Self Renewal - genetics | Forkhead Box Protein O3 - genetics | Drug Resistance, Neoplasm - genetics | Neoplasms - genetics | Forkhead Box Protein M1 - genetics | Cell Proliferation - drug effects | Neoplasms - pathology | Drug Resistance, Neoplasm - drug effects | Drug resistance in microorganisms | Chromatin | Endothelial growth factors | Leukemia | DNA damage | Estrogen | Disease susceptibility | Biological response modifiers | T cells | DNA repair | Epidermal growth factor | Nucleotide sequencing | Drug therapy | Protein kinases | Health aspects | Protein binding | Tyrosine | Niacinamide | Superoxide | DNA binding proteins | Cell differentiation | Chemotherapy | Multiprocessing | Gliomas | Stem cells | Interferon | Lymphomas | Adenylic acid | Mitogens | Cancer | DNA sequencing | Index Medicus | AURKA, aurora kinase A | Fox, forkhead box | Bim, B-cell lymphoma 2 interacting mediator | EGF, epidermal growth factor | JNK | BRIP1, BRCA1-interacting protein-terminal helicase 1 | GICs, glioma-initiating cells | MCL, mantle cell lymphoma | PKB, protein kinase B | SCs, stem cells | LEF, T-cell factor | Skp2, S-phase kinase-associated protein 2 | SSBs, single-strand breaks | mTOR, mammalian target of rapamycin | NBS1, Nijmegen breakage syndrome 1 | stress activated protein kinase | MEK, mitogen-activated protein kinase kinase | PIP3, phosphatidylinositol- 3,4,5-trisphosphate | BER, base excision repair | lymphoid enhancer factor | VEGF, vascular endothelial growth factor | AML, acute myeloid leukaemia | ER+ve, estreogen receptor positive | EXO1, exonuclease 1 | EGFR, epidermal growth factor receptor | MDR1, multidrug resistance protein 1 | ChIP-seq, chromatin immunoprecipitation with massively parallel DNA sequencing | ABCB1, ATP-binding cassette sub-family B member 1 | TCF | SOD-2, superoxide dismutase | TKIs, tyrosine kinase inhibitors | PDK, phosphoinositide-dependent kinase | IFNɣ, interferon-ɣ | BRCA2, breast cancer-associated gene 2 | DDR, DNA damage response | Cks1, cyclin-dependent kinases regulatory subunit 1 | ESR1, estrogen receptor alpha gene | NHEJ, non-homologous end joining | XRCC1, X-ray cross-complementing group 1 | OTUB1, OUT domain-containing ubiquitin aldehyde-binding protein 1 | IGF, insulin growth factor | TRAIL, tumour necrosis factor-related apoptosis inducing ligand | ER, estrogen receptor | MRN, MER11-RAD50-NBS1 | BRCA1, breast cancer susceptibility gene product 1 | FasL, fas ligand | RTKs, receptor tyrosine kinases | Sox1, sex determining region Y box 2 | GADD45, DNA damage-inducible protein 45 | MMR, mismatch repair | PI3K, phosphatidylinositol 3-kinase | ROS, reactive oxygen species | NAMPT, nicotinamide-phosphribosyltransferase | miRs, Micro-RNAs | FHRE, forkhead response element | ATM, Ataxia-telangiectasia mutated | NER, nucleotide excision repair | ERK, extracellular signal-regulated kinase | HR, homologous recombination | AMPK, adenosine monophosphate-activated protein kinase | DSBs, double strands breaks | PA, Psammaplysene A | CML, chronic myeloid leukaemia | HCC, hepatocellular carcinoma | Mst1, macrophage stimulating 1 | Rb2, retinoblastoma-related p130 | SAPK, c-Jun N-terminal kinase | CSCs, cancer stem cells
Journal Article
Biochemical pharmacology, ISSN 0006-2952, 08/2018, Volume 154, pp. 424 - 434
Infection | Multi-tRNA synthetase complex | Antibiotics | Aminoacyl-tRNA synthetase | Antiviral immunity | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Humans | Protein Biosynthesis - physiology | Anti-Bacterial Agents - metabolism | Antiviral Agents - metabolism | Antiviral Agents - administration & dosage | Communicable Diseases - metabolism | Animals | Communicable Diseases - drug therapy | Signal Transduction - drug effects | Protein Biosynthesis - drug effects | Signal Transduction - physiology | Drug Delivery Systems - trends | Amino Acyl-tRNA Synthetases - metabolism | Anti-Bacterial Agents - administration & dosage | Drug Delivery Systems - methods | Microbial Sensitivity Tests - methods | Amino Acyl-tRNA Synthetases - antagonists & inhibitors | C-reactive protein | Communicable diseases | HIV (Viruses) | Biological response modifiers | Materia medica and therapeutics | Proteins | Interleukins | Bone morphogenetic proteins | Research institutes | Aminoacyl-tRNA synthetases | Health aspects | Protein kinases | Protein binding | Tretinoin | Transfer RNA | Post-translational modification | Antiviral agents | Medical research | Chromosomal proteins | Dendritic cells | Melanoma | Protein biosynthesis | Transforming growth factors | Homeopathy | Therapeutics | Medicine, Experimental | Hepatitis C virus | Mitogens | Index Medicus | PTM, post-translational modification | RIG-I, retinoic acid-inducible gene-I | MDA5, melanoma differentiation-associated protein 5 | WT, wild-type | GAIT, IFN-γ-activated inhibition of translation | HCV, hepatitis C virus | TLS, tRNA-like structure | MAVS, mitochondrial antiviral signaling protein | IL-1β, interleukin-1β | AA-AMP, aminoacyl-adenylate | ITCH, E3 ubiquitin-protein ligase Itchy homolog | Oas, 2′-5′-oligoadenylate synthase | AIMP, ARS-interacting multifunctional protein | HMGB1, high mobility group box 1 | TH1, T-helper type 1 | TRAIL, tumor necrosis factor-related apoptosis-inducing ligand | MSC, multi-tRNA synthetase complex | PBMC, peripheral blood mononuclear cell | BMDM, bone marrow-derived macrophage | ARS, aminoacyl-tRNA synthetase | TLR, toll-like receptor | IFN, interferon | eEF1A, eukaryotic elongation factor 1 alpha | EMAPII, endothelial monocyte-activating polypeptide II | BMDC, bone marrow-derived dendritic cell | HIV, human immunodeficiency virus | MITF, microphthalmia-associated transcription factor | TGF-β, tumor growth factor-β | ERK, extracellular-related kinase | PCBP2, poly(rC)-binding protein 2 | TNF-α, tumor necrosis factor-α | IP-10, interferon-inducible protein 10 | IFN-α, interferon-α | MEK, MAPK kinase kinase | TCID50, a median tissue culture infective dose | LPS, lipopolysaccharide | CRP, C-reactive protein | MAPK, mitogen-activated protein kinase
Journal Article
5.