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Journal Article
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 05/2009, Volume 119, Issue 5, pp. 1201 - 1215
Hepatic steatosis is present in insulin-resistant obese rodents and is concomitant with active lipogenesis. Hepatic lipogenesis depends on the insulin-induced... 
MEDICINE, RESEARCH & EXPERIMENTAL | GLUCOSE-HOMEOSTASIS | FATTY-ACID SYNTHESIS | ELEMENT-BINDING PROTEIN-1C | ENZYME GENES | LIPOGENIC GENE-EXPRESSION | ENDOPLASMIC-RETICULUM STRESS | COPII PROTEINS | TRANSCRIPTION FACTOR | DIFFERENTIAL REGULATION | LIVER-X-RECEPTOR | Molecular Chaperones - metabolism | Gene Expression - drug effects | Rats, Wistar | Fatty Liver - pathology | Gene Expression - genetics | Endoplasmic Reticulum - metabolism | Fatty Liver - therapy | Male | Hepatocytes - metabolism | Insulin Receptor Substrate Proteins - metabolism | Heat-Shock Proteins - genetics | Insulin Resistance - physiology | Endoplasmic Reticulum - drug effects | Lipid Metabolism - genetics | Sterol Regulatory Element Binding Protein 2 - metabolism | Nuclear Proteins - genetics | Hepatocytes - drug effects | Sterol Regulatory Element Binding Protein 1 - metabolism | Insulin - pharmacology | Fatty Liver - metabolism | Heat-Shock Proteins - metabolism | Liver - metabolism | Molecular Chaperones - genetics | Rats | Nuclear Proteins - metabolism | Signal Transduction - genetics | Transcription Factors - genetics | Obesity - metabolism | Rats, Zucker | Transcription Factors - metabolism | Animals | Sterol Regulatory Element Binding Protein 1 - genetics | Models, Biological | Glucose - metabolism | Thapsigargin - pharmacology | Mice, Obese | Mice | Care and treatment | Liver diseases | Physiological aspects | Heat shock proteins | Insulin resistance | Genetic aspects | Research | Endoplasmic reticulum | Health aspects | Risk factors
Journal Article