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Journal of Clinical Investigation, ISSN 0021-9738, 07/2013, Volume 123, Issue 7, pp. 2921 - 2934
Journal Article
Nature Cell Biology, ISSN 1465-7392, 03/2010, Volume 12, Issue 3, pp. 213 - 223
Impaired selective turnover of p62 by autophagy causes severe liver injury accompanied by the formation of p62-positive inclusions and upregulation of... 
OXIDATIVE STRESS | PROTEIN | MECHANISM | CUL3-BASED E3 LIGASE | STRUCTURAL BASIS | DLG MOTIFS | DEGRADATION | MICE | BETA-CELL MASS | INDUCTION | CELL BIOLOGY | Adaptor Proteins, Signal Transducing - chemistry | Liver - pathology | Microtubule-Associated Proteins - genetics | Cytoskeletal Proteins - genetics | Gene Expression - genetics | Protein Interaction Domains and Motifs - physiology | Sequestosome-1 Protein | Humans | Oxidative Stress - physiology | Crystallography, X-Ray | Hepatocytes - pathology | Autophagy - physiology | Intracellular Signaling Peptides and Proteins - metabolism | Hepatocytes - metabolism | Liver - physiopathology | Heat-Shock Proteins - genetics | Mutation - physiology | Transfection | Organ Size - genetics | Cytoskeletal Proteins - metabolism | NF-E2-Related Factor 2 - genetics | Inclusion Bodies - metabolism | Kelch-Like ECH-Associated Protein 1 | Cell Line | Binding, Competitive - physiology | Heat-Shock Proteins - metabolism | Liver - metabolism | Models, Molecular | Mice, Transgenic | Cytoskeletal Proteins - chemistry | Mice, Knockout | Protein Interaction Mapping | Autophagy-Related Protein 7 | Animals | Models, Biological | NF-E2-Related Factor 2 - metabolism | Adaptor Proteins, Signal Transducing - genetics | Calorimetry | Signal Transduction - physiology | Mice | Adaptor Proteins, Signal Transducing - metabolism | Heat-Shock Proteins - chemistry | Protein Binding - physiology | Autophagy (Cytology) | Care and treatment | Transcription factors | Liver diseases | Physiological aspects | Genetic aspects | Research | Index Medicus
Journal Article
Biochemical Journal, ISSN 0264-6021, 01/2004, Volume 377, Issue 1, pp. 205 - 213
TCDD (2,3,7,8-tetrachlorodibenzo-p-dixoin) induces phase II drug-metabolizing enzyme NQO1 [NAD(P)H:quinone oxidoreductase; EC 1.6.99.2; DT-diaphorase] in a... 
AhR (aryl hydrocarbon receptor) | DRE (dioxin response element) | TCDD (2,3,7,8-tetrachlorodibenzo-p- dioxin) | ARE (antioxidant response element) | NQO1 [NAD(P)H:quinone oxidoreductase 1] | Nrf2 (nuclear factor erythroid 2-related factor 2) | NQO1 [NAD(P)H : quinone oxidoreductase 1] | BIOCHEMISTRY & MOLECULAR BIOLOGY | MOUSE | POLYMORPHISM | IDENTIFICATION | ANTIOXIDANT RESPONSE ELEMENT | CARCINOGENESIS | DT-DIAPHORASE | NQO1 GENE | GENE-EXPRESSION | TCDD (2,3,7,8-tetrachlorodibenzo-p-dioxin) | UBIQUITIN-PROTEASOME PATHWAY | INDUCIBLE EXPRESSION | Leucine Zippers | Multienzyme Complexes - metabolism | NAD(P)H Dehydrogenase (Quinone) - genetics | Hydroquinones - pharmacology | Proteasome Endopeptidase Complex | Trans-Activators - chemistry | Trans-Activators - physiology | DNA-Binding Proteins - metabolism | Cysteine Endopeptidases - metabolism | Polychlorinated Dibenzodioxins - pharmacology | Receptors, Aryl Hydrocarbon - metabolism | Transcription, Genetic | Protein Synthesis Inhibitors - pharmacology | Ubiquitins - metabolism | DNA-Binding Proteins - physiology | Signal Transduction | Cells, Cultured | Enzyme Induction | Antioxidants - pharmacology | DNA-Binding Proteins - chemistry | Cycloheximide - pharmacology | NAD(P)H Dehydrogenase (Quinone) - biosynthesis | Animals | Cell Line, Tumor | NAD(P)H Dehydrogenase (Quinone) - metabolism | Ligands | NF-E2-Related Factor 2 | Trans-Activators - metabolism | Mice | Index Medicus
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 07/2010, Volume 285, Issue 29, pp. 22576 - 22591
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 03/2012, Volume 52, Issue 5, pp. 928 - 936
Interest in histone deacetylase (HDAC)-based therapeutics as a potential treatment for stroke has grown dramatically. The neuroprotection of HDAC inhibition... 
HDAC inhibition | Cerebral ischemia | TSA | Nrf2 | OXIDATIVE STRESS | SUBEROYLANILIDE HYDROXAMIC ACID | BRAIN-INJURY | ANTICANCER AGENTS | GINKGO-BILOBA | BIOCHEMISTRY & MOLECULAR BIOLOGY | NEURONAL CELL-DEATH | MOUSE MODEL | ENDOCRINOLOGY & METABOLISM | NRF2-MEDIATED ANTIOXIDANT RESPONSE | GENE-EXPRESSION | INTRACEREBRAL HEMORRHAGE | Neuroprotective Agents - therapeutic use | Cytoskeletal Proteins - genetics | Male | Luciferases - genetics | Cell Hypoxia | Neuroprotective Agents - pharmacology | Neurons - physiology | Cytoskeletal Proteins - metabolism | Female | NF-E2-Related Factor 2 - genetics | Neurons - drug effects | Hydroxamic Acids - pharmacology | Kelch-Like ECH-Associated Protein 1 | Genes, Reporter | Cell Survival - drug effects | Gene Expression | Response Elements | Mice, Inbred C57BL | Cells, Cultured | Mice, Knockout | Gene Expression Regulation - drug effects | Animals | Brain Ischemia - drug therapy | NF-E2-Related Factor 2 - metabolism | Adaptor Proteins, Signal Transducing - genetics | Brain Ischemia - pathology | Protein Binding | Histone Deacetylase Inhibitors - pharmacology | Hydroxamic Acids - therapeutic use | Histone Deacetylase Inhibitors - therapeutic use | Mice | Adaptor Proteins, Signal Transducing - metabolism | Luciferases - biosynthesis | Antioxidants | Cysteine | Surface active agents | Ligases | Heme | Histones | DNA binding proteins | Glucose | Sulfates | Glutamate | Dextrose | Phosphates | Glucose metabolism | Glutamate-cysteine ligase | Brain | Cell culture | Histone deacetylase | Neuroprotection | Oxygen | Stroke | Transcription factors | Neurons | Regulatory sequences | Nuclear transport | Ischemia | quinone oxidoreductase | Trichostatin A | Acetylation | Catalytic subunits | Index Medicus
Journal Article
Antioxidants & Redox Signaling, ISSN 1523-0864, 06/2011, Volume 14, Issue 12, pp. 2347 - 2360
Journal Article
Journal Article
Molecular and Cellular Biology, ISSN 0270-7306, 01/2005, Volume 25, Issue 1, pp. 162 - 171
Journal Article
Journal Article
Kidney International, ISSN 0085-2538, 02/2017, Volume 91, Issue 2, pp. 387 - 401
Journal Article