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Journal of Neurology, Neurosurgery and Psychiatry, ISSN 0022-3050, 05/2019, Volume 90, Issue 5, pp. 529 - 536
Objective The aim of this study was to evaluate the efficacy and safety of high-dose taurine supplementation for prevention of stroke-like episodes of MELAS... 
ENCEPHALOPATHY | SURGERY | WOBBLE MODIFICATION DEFICIENCY | PSYCHIATRY | TRANSFER RNALEU(UUR) GENE | MODIFICATION DEFECT | MUTATION | LACTIC-ACIDOSIS | TRANSFER-RNA | MITOCHONDRIAL MYOPATHY | CLINICAL NEUROLOGY | Neurology | Stroke | Medical prognosis | Clinical trials | Mitochondrial DNA | Clinical medicine | Mutation | Neurogenetics | 1506
Journal Article
FASEB JOURNAL, ISSN 0892-6638, 08/2011, Volume 25, Issue 8, pp. 2669 - 2687
Mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS) is a mitochondrial disease most usually caused by point mutations in tRNA... 
free radicals | autophagy | BIOCHEMISTRY & MOLECULAR BIOLOGY | PROTEIN-SYNTHESIS | PERMEABILITY TRANSITION | CELL-DEATH | CELL BIOLOGY | mitochondrial diseases | DNA | TRANSFER RNALEU(UUR) GENE | MUTATION | BIOLOGY | STROKE-LIKE EPISODES | LACTIC-ACIDOSIS | TRANSFER-RNA
Journal Article
Molecular Neurobiology, ISSN 0893-7648, 1/2019, Volume 56, Issue 1, pp. 321 - 334
Journal Article
Journal Article
CELL BIOCHEMISTRY AND BIOPHYSICS, ISSN 1085-9195, 04/2015, Volume 71, Issue 3, pp. 1589 - 1603
Conformational preferences of hypermodified nucleoside 5-taurinomethyluridine 5'-monophoshate 'p-tau m(5)U' (-CH2-NH2 (+)-CH2-CH2-SO3 (-)) have been... 
POINT MUTATION | tRNA | BIOCHEMISTRY & MOLECULAR BIOLOGY | MITOCHONDRIAL TRANSFER-RNAS | MYOPATHY | MELAS SUBGROUP | CELL BIOLOGY | ENCEPHALOPATHY | DFT | BIOPHYSICS | RM1 | TRANSFER RNALEU(UUR) GENE | Molecular electrostatics potential (MEPs) | STROKE-LIKE EPISODES | LACTIC-ACIDOSIS | ADENINE | TAURINE | tau mU
Journal Article
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 08/1994, Volume 202, Issue 3, pp. 1624 - 1630
A new point mutation at nucleotide pair 3291 in the mitochondrial tRNA-Leu(UUR) gene was found in a Japanese MELAS patient. The nucleotides at the mutated site... 
MELAS Syndrome - genetics | Point Mutation | Animals | Base Sequence | Humans | RNA, Mitochondrial | Molecular Sequence Data | Male | Child | Sequence Homology, Nucleic Acid | RNA, Transfer, Leu - genetics | RNA - genetics | Index Medicus
Journal Article
Journal Article
NUCLEAR MEDICINE AND BIOLOGY, ISSN 0969-8051, 02/2012, Volume 39, Issue 2, pp. 177 - 185
Objectives: Radiolabeled Cu-diacetyl-bis (N-4-methylthiosemicarbazone) (*Cu-ATSM), including Cu-60/62/64-ATSM, is a potential imaging agent of hypoxic tumors... 
rho cell | OXIDATIVE STRESS | Mitochondrial dysfunction | POINT MUTATION | Cu-ATSM | CERVICAL-CANCER | CU-64-ATSM | Overreduced state | IN-VITRO | POSITRON-EMISSION-TOMOGRAPHY | TRANSFER RNALEU(UUR) GENE | ASSESSING TUMOR HYPOXIA | LACTIC-ACIDOSIS | MELAS | PIMONIDAZOLE | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | PET
Journal Article
European Journal of Neurology, ISSN 1351-5101, 04/2017, Volume 24, Issue 4, pp. 587 - 593
Journal Article
SEMINARS IN PEDIATRIC NEUROLOGY, ISSN 1071-9091, 11/2016, Volume 23, Issue 4, pp. 290 - 305
Mitochondrial diseases exhibit significant clinical and genetic heterogeneity. Mitochondria are highly dynamic organelles that are the major contributor of... 
PROGRESSIVE EXTERNAL OPHTHALMOPLEGIA | MULTIPLE MTDNA DELETIONS | DNA-POLYMERASE-GAMMA | MARIE-TOOTH-DISEASE | C-OXIDASE DEFICIENCY | TRANSFER RNALEU(UUR) GENE | NEUROGASTROINTESTINAL ENCEPHALOMYOPATHY MNGIE | PEDIATRICS | COMPLEX I DEFICIENCY | MITOFUSIN 2 MUTATIONS | CEREBRAL FOLATE-DEFICIENCY | CLINICAL NEUROLOGY
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 11/2012, Volume 167, Issue 6, pp. 1311 - 1328
Journal Article