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Organic & Biomolecular Chemistry, ISSN 1477-0520, 06/2017, Volume 15, Issue 25, pp. 5332 - 5336
S-Geranylated 2-thiouridines (geS2Us) are unique hydrophobic modified nucleosides identified very recently in bacterial tRNAs. Our study on the synthesis of... 
Journal Article
NATURE COMMUNICATIONS, ISSN 2041-1723, 06/2016, Volume 7
Epitranscriptome modifications are required for structure and function of RNA and defects in these pathways have been associated with human disease. Here we... 
METHYLTRANSFERASE MISU NSUN2 | NONCODING RNA | HYPERTROPHIC CARDIOMYOPATHY | 5-METHYLCYTOSINE | DNA | MULTIDISCIPLINARY SCIENCES | BOVINE LIVER | MITOCHONDRIAL TRANSFER-RNAS | ANTICODON | 5-FORMYLCYTOSINE | GENOME
Journal Article
Cold Spring Harbor perspectives in biology, ISSN 1943-0264, 10/2018, Volume 10, Issue 10
Termination of mRNA translation occurs when a stop codon enters the A site of the ribosome, and in eukaryotes is mediated by release factors eRF1 and eRF3,... 
COGNATE TRANSFER-RNAS | OPEN READING FRAMES | MESSENGER-RNA | STRUCTURAL BASIS | CRYSTAL-STRUCTURE | CRYO-EM | PEPTIDE RELEASE | STOP CODON RECOGNITION | GTP HYDROLYSIS | RELEASE FACTOR ERF1 | CELL BIOLOGY
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 02/2018, Volume 46, Issue 4, pp. 1565 - 1583
Abstract Modified uridine containing taurine, 5-taurinomethyluridine (τm5U), is found at the anticodon first position of mitochondrial (mt-)transfer RNAs... 
JAPANESE FLOUNDER | HYPERTROPHIC CARDIOMYOPATHY | WOBBLE MODIFICATION DEFICIENCY | MUTANT TRANSFER-RNAS | BIOCHEMISTRY & MOLECULAR BIOLOGY | MODIFICATION DEFECT | MITOCHONDRIAL TRANSFER-RNAS | STROKE-LIKE EPISODES | LACTIC-ACIDOSIS | CLINICAL-FEATURES | ONE-CARBON METABOLISM | NAR Breakthrough
Journal Article
Drug Discovery Today, ISSN 1359-6446, 04/2014, Volume 19, Issue 4, pp. 388 - 399
We describe a new discovery technology that uses mRNA-display to rapidly synthesize and screen macrocyclic peptide libraries to explore a valuable region of... 
ELONGATION-FACTOR TU | UNNATURAL PEPTIDES | PERMEABILITY | IN-VITRO SELECTION | RIBOSOMAL SYNTHESIS | PHARMACOLOGY & PHARMACY | AMINOACYL-TRANSFER-RNAS | TRANSLATION | N-METHYLATION | BINDING | CYCLIC-PEPTIDES | Biological Products | RNA, Messenger - chemistry | Peptide Library | Peptides - chemistry | Drug Discovery | Messenger RNA
Journal Article
Cell, ISSN 0092-8674, 07/2016, Volume 166, Issue 3, pp. 691 - 702
Journal Article
NATURE CHEMICAL BIOLOGY, ISSN 1552-4450, 10/2010, Volume 6, Issue 10, pp. 733 - 740
Adenosine-to-inosine (A-to-I) RNA editing is a post-transcriptional processing event involved in diversifying the transcriptome responsible for various... 
INTERFERON | MESSENGER-RNA | GENE | PSEUDOURIDINE | BIOCHEMISTRY & MOLECULAR BIOLOGY | ADENOSINE DEAMINATION | GLUR-B | MITOCHONDRIAL TRANSFER-RNAS | EXPRESSION | TRANSFER RIBONUCLEIC ACID | ENZYME ADAR1
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 07/2019, Volume 47, Issue 12, pp. 6339 - 6350
Abstract Stop codon readthrough—the decoding of a stop codon by a near-cognate tRNA—is employed by viruses to balance levels of enzymatic and structural... 
STOP CODON READTHROUGH | COGNATE TRANSFER-RNAS | MESSENGER-RNA | NONSENSE | DOWNSTREAM | BIOCHEMISTRY & MOLECULAR BIOLOGY | TERMINATION CODONS | SUPPRESSION | EUKARYOTIC RELEASE FACTOR-1 | CONTEXT | BASE | Molecular Biology
Journal Article
by Ho, AT and Hurst, LD
PLOS GENETICS, ISSN 1553-7404, 09/2019, Volume 15, Issue 9
Author summary In all organisms, gene expression is error-prone. One such error, translational read-through, occurs where the primary stop codon of an... 
PEPTIDE-CHAIN TERMINATION | COGNATE TRANSFER-RNAS | IN-VITRO | MESSENGER-RNA | RELEASE FACTORS RF1 | TRANSLATIONAL TERMINATION | NONSENSE | ESCHERICHIA-COLI | GENETICS & HEREDITY | EFFICIENCY | UGA
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 02/2019, Volume 47, Issue 3, pp. 1164 - 1177
Abstract Synonymous codons provide redundancy in the genetic code that influences translation rates in many organisms, in which overall codon use is driven by... 
GENOME DATABASE | TRANSFER-RNAS | USAGE | PREFERENCES | ELONGATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI | EXPRESSED GENES | MUTATION BIAS | SEQUENCE | EFFICIENCY | Computational Biology
Journal Article
Biochemistry, ISSN 0006-2960, 02/2019, Volume 58, Issue 5, pp. 299 - 304
Since their initial discovery, tRNAs have risen from sole adapter molecules during protein synthesis to pivotal modulators of gene expression. Through their... 
LACKING | ENZYME | MESSENGER-RNA | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI | EXOSOME | DEGRADATION | MITOCHONDRIAL TRANSFER-RNAS | ELONGATION-FACTOR-TU | BINDING | MINIMAL TRANSFER-RNA
Journal Article