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Journal Article
Journal Article
Cold Spring Harbor Perspectives in Biology, ISSN 1943-0264, 09/2011, Volume 3, Issue 9, pp. 1 - 16
Journal Article
Nature reviews. Cancer, ISSN 1474-1768, 2007, Volume 7, Issue 9, pp. 654 - 658
Journal Article
PloS one, ISSN 1932-6203, 2012, Volume 7, Issue 12, p. e51432
...). A commonly used mouse model for AD is 3xTg-AD mouse, which is generated by over-expression of mutated presenilin 1, APP and tau in the brain and thus represents a mouse model of FAD... 
ACTIVATION | PRESENILINS | CALPAIN | GLUCOSE-METABOLISM | INSULIN-RESISTANCE | MULTIDISCIPLINARY SCIENCES | A-BETA | SIGNALING MECHANISMS | TAU | TRIPLE-TRANSGENIC MODEL | DEGENERATION | Alzheimer Disease - etiology | DNA, Complementary - genetics | Real-Time Polymerase Chain Reaction - methods | Transcriptome | Gene Expression Regulation - physiology | Reverse Transcriptase Polymerase Chain Reaction | Cerebral Cortex - metabolism | Hippocampus - metabolism | Animals | Presenilin-1 - metabolism | Alzheimer Disease - metabolism | Mice | Streptozocin - toxicity | Alzheimer Disease - genetics | Disease Models, Animal | Type 2 diabetes | Brain | Advertising executives | Analysis | Genes | Physiological aspects | Genetic aspects | Gene expression | Protein kinases | Alzheimer's disease | TOR protein | Drugs | Neurosciences | Animal models | Cerebral cortex | Streptozocin | Neurobiology | Glucose | Drug development | Kinases | Protein turnover | Proteins | Glucose metabolism | Etiology | Rodents | Neurochemistry | Neurodegenerative diseases | Metabolism | Insulin | Amyloid precursor protein | Studies | Neurology | Signaling | Brain research | Overexpression | Tau protein | Presenilin 1 | Cytoskeleton | Insulin resistance | Diabetes | Mutation | Alzheimers disease | Hippocampus | Developmental disabilities | Phagocytosis | Apoptosis | Dementia | Animal cognition
Journal Article
Journal of neurochemistry, ISSN 0022-3042, 2013, Volume 125, Issue 3, pp. 410 - 419
...; recent studies demonstrated that PPAR‐γ activation prevented mitochondrial depolarization in cells expressing mutant HTT and attenuated neurodegeneration in various models of neurodegenerative diseases. PPAR‐γ‐coactivator 1α (PGC‐1 α... 
PPAR‐γ | BDNF | glucose metabolism | Sirt6 | huntingtin | PGC‐1α | PGC-1α | PPAR-γ | BDNF LEVELS | TRANSGENIC MOUSE | NEUROTROPHIC FACTOR | PGC-1-ALPHA | BIOCHEMISTRY & MOLECULAR BIOLOGY | AMYOTROPHIC-LATERAL-SCLEROSIS | NEUROSCIENCES | TRANSCRIPTIONAL DYSREGULATION | PPAR | PGC-1 | ACTIVATED-RECEPTOR-GAMMA | MITOCHONDRIAL DYSFUNCTION | ENERGY-METABOLISM | PARKINSONS-DISEASE | L-Lactate Dehydrogenase - metabolism | Neuroprotective Agents - therapeutic use | Humans | Huntington Disease - pathology | Brain - enzymology | Male | Intracellular Signaling Peptides and Proteins - metabolism | RNA, Messenger - metabolism | Hyperglycemia - drug therapy | Thiazolidinediones - therapeutic use | Neuroprotective Agents - pharmacology | Transfection | Adenosine Triphosphate - metabolism | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Trans-Activators - genetics | Brain-Derived Neurotrophic Factor - metabolism | Neurons - metabolism | Huntington Disease - drug therapy | Neurons - drug effects | Thiazolidinediones - pharmacology | Disease Models, Animal | Cell Line | Orexins | Gene Expression Regulation - genetics | Glutamates - genetics | Mice, Transgenic | Neuropeptides - metabolism | Nerve Tissue Proteins - genetics | Brain - drug effects | Gene Expression Regulation - drug effects | Huntington Disease - complications | Huntingtin Protein | Animals | PPAR gamma - antagonists & inhibitors | Movement Disorders - etiology | Anilides - pharmacology | Brain - pathology | Huntington Disease - genetics | Trinucleotide Repeat Expansion - genetics | Trans-Activators - metabolism | Hyperglycemia - etiology | Mice | Transcription Factors | Sirtuins - metabolism | Movement Disorders - drug therapy | Index Medicus
Journal Article
Cellular and molecular life sciences : CMLS, ISSN 1420-9071, 2011, Volume 69, Issue 7, pp. 1153 - 1165
Journal Article
Nature medicine, ISSN 1546-170X, 2014, Volume 20, Issue 10, pp. 1157 - 1164
Journal Article