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Arteriosclerosis, thrombosis, and vascular biology, ISSN 1079-5642, 2014, Volume 34, Issue 2, pp. 279 - 284
Liver X receptor (LXR) activators decrease atherosclerosis in mice. LXR activators (1) directly upregulate genes involved in reverse cholesterol transport and... 
atherosclerosis | ATP-binding cassette transporters | macrophages | liver X receptor | inflammation | ANTIINFLAMMATORY ACTIVITY | MYELOPROLIFERATIVE DISORDERS | LDL RECEPTOR | TERTIARY-AMINES | ACCELERATES ATHEROSCLEROSIS | KNOCKOUT MICE | NUCLEAR RECEPTOR | REVERSE CHOLESTEROL TRANSPORT | MACROPHAGE ABCA1 | GENE-EXPRESSION | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | Lipoproteins - deficiency | Macrophages - transplantation | ATP Binding Cassette Transporter, Sub-Family G, Member 1 | Lipoproteins - genetics | Atherosclerosis - genetics | Hydrocarbons, Fluorinated - pharmacology | Male | Aorta - metabolism | Orphan Nuclear Receptors - metabolism | ATP-Binding Cassette Transporters - deficiency | ATP-Binding Cassette Transporters - genetics | Biological Transport | Liver X Receptors | Myocardium - metabolism | Bone Marrow Transplantation | Inflammation Mediators - metabolism | Receptors, LDL - deficiency | Female | Cytokines - genetics | Macrophages - immunology | Disease Models, Animal | Receptors, LDL - genetics | Atherosclerosis - pathology | Atherosclerosis - immunology | Cytokines - metabolism | Anti-Inflammatory Agents - pharmacology | Aorta - drug effects | Mice, Inbred C57BL | Orphan Nuclear Receptors - agonists | Gene Expression Regulation | Myocardium - pathology | Cholesterol - metabolism | Sulfonamides - pharmacology | Atherosclerosis - metabolism | Mice, Knockout | Aorta - pathology | Macrophages - metabolism | Animals | Lipopolysaccharides - pharmacology | ATP Binding Cassette Transporter 1 - deficiency | Benzoates - pharmacology | Macrophages - drug effects | Mice | Benzylamines - pharmacology | Atherosclerosis - prevention & control | ATP Binding Cassette Transporter 1 - genetics | Index Medicus
Journal Article
Journal Article
Journal Article
Experimental Cell Research, ISSN 0014-4827, 08/2015, Volume 336, Issue 1, pp. 33 - 42
Journal Article
Journal Article
Circulation research, ISSN 0009-7330, 2013, Volume 112, Issue 11, pp. 1456 - 1465
Rationale: Plasma high-density lipoprotein levels are inversely correlated with atherosclerosis. Although it is widely assumed that this is attributable to the... 
atherosclerosis | monocytes | macrophages | inflammation | high-density lipoprotein | ABCA1 | CARDIAC & CARDIOVASCULAR SYSTEMS | STEM-CELL PROLIFERATION | APOA-I | LESIONS | HIGH-DENSITY-LIPOPROTEIN | TANGIER-DISEASE | LIPID-ACCUMULATION | EFFLUX | GENE | REVERSE CHOLESTEROL TRANSPORT | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | ATP Binding Cassette Transporter, Sub-Family G, Member 1 | Lipoproteins - genetics | Atherosclerosis - genetics | Cholesterol, Dietary - metabolism | Vasculitis - pathology | Monocytes - metabolism | Monocytes - immunology | Vasculitis - immunology | Vasculitis - genetics | ATP-Binding Cassette Transporters - genetics | Bone Marrow Transplantation | Lipoproteins - metabolism | Monocytes - pathology | ATP-Binding Cassette Transporters - metabolism | ATP Binding Cassette Transporter 1 | Spleen - pathology | Foam Cells - pathology | Neutrophils - metabolism | Foam Cells - metabolism | Macrophages - immunology | Neutrophils - pathology | Receptors, LDL - genetics | Atherosclerosis - pathology | Atherosclerosis - immunology | Macrophages - pathology | Neutrophils - immunology | Receptors, LDL - metabolism | Mice, Knockout | Macrophages - metabolism | Animals | Foam Cells - immunology | Mice | ATP-Binding Cassette Transporters - immunology | Lipoproteins - immunology | Animal Feed | Index Medicus
Journal Article
Atherosclerosis, ISSN 0021-9150, 2014, Volume 236, Issue 1, pp. 215 - 226
Journal Article
Clinical and Experimental Pharmacology and Physiology, ISSN 0305-1870, 12/2014, Volume 41, Issue 12, pp. 1023 - 1030
Adenosine triphosphate‐binding cassette transporter A1 (ABCA1) and ABCG1 play crucial roles in reverse cholesterol transport, and have anti‐atherosclerosis... 
liver X receptor α | reverse cholesterol transport | angiotensin‐(1–7) | adenosine triphosphate‐binding cassette transporter A1 | adenosine triphosphate‐binding cassette transporter G1 | Liver X receptor α | Adenosine triphosphate-binding cassette transporter G1 | Adenosine triphosphate-binding cassette transporter A1 | Angiotensin-(1-7) | Reverse cholesterol transport | PHYSIOLOGY | LXR | INCREASES | ATHEROSCLEROSIS | MECHANISMS | liver X receptor alpha | FOAM CELLS | adenosine triphosphate-binding cassette transporter G1 | SMOOTH-MUSCLE | EFFLUX | adenosine triphosphate-binding cassette transporter A1 | ATHEROPROTECTION | INFLAMMATION | angiotensin-(1-7) | PHARMACOLOGY & PHARMACY | RNA, Small Interfering - genetics | ATP Binding Cassette Transporter, Sub-Family G, Member 1 | Atherosclerosis - genetics | Humans | RNA, Messenger - genetics | Proto-Oncogene Proteins - genetics | Up-Regulation - genetics | Signal Transduction - genetics | Cholesterol - metabolism | Orphan Nuclear Receptors - genetics | Macrophages - metabolism | ATP-Binding Cassette Transporters - genetics | Angiotensin I - genetics | Membrane Transport Proteins - genetics | Liver X Receptors | Cell Line, Tumor | Receptors, G-Protein-Coupled - genetics | Peptide Fragments - genetics | ATP Binding Cassette Transporter 1 - genetics | RNA | Liver | Atherosclerosis | Angiotensin | Muscle proteins | Macrophages | Adenosine triphosphate | Index Medicus
Journal Article
Journal Article
Arteriosclerosis thrombosis and vascular biology, ISSN 1079-5642, 06/2016, Volume 36, Issue 7, pp. 1328 - 1337
Objective-Plasma high-density lipoproteins have several putative antiatherogenic effects, including preservation of endothelial functions. This is thought to... 
atherosclerosis | ATP-binding cassette transporters | Hypercholesterolemia | Endothelium | endothelium | ACTIVATION | NITRIC-OXIDE SYNTHASE | LINEAGE ANALYSIS | ADHESION MOLECULES | KNOCKOUT MICE | hypercholesterolemia | HIGH-DENSITY-LIPOPROTEIN | HEART-DISEASE | GENE-EXPRESSION | PERIPHERAL VASCULAR DISEASE | HDL CHOLESTEROL | HEMATOLOGY | CORONARY-ARTERY-DISEASE | Whole-Body Irradiation | ATP Binding Cassette Transporter, Subfamily G, Member 1 - deficiency | Atherosclerosis - genetics | Male | Monocytes - metabolism | Retinal Neovascularization - metabolism | Aortic Diseases - metabolism | ATP Binding Cassette Transporter, Subfamily G, Member 1 - genetics | Time Factors | Diet, High-Fat | Bone Marrow Transplantation | Inflammation Mediators - metabolism | Receptors, LDL - deficiency | Retinal Neovascularization - genetics | Nitric Oxide Synthase Type III - metabolism | Aorta, Thoracic - pathology | Aortic Diseases - pathology | Disease Models, Animal | Receptors, LDL - genetics | Atherosclerosis - pathology | Genetic Predisposition to Disease | Atherosclerosis - physiopathology | Endothelial Cells - metabolism | Tissue Culture Techniques | Aorta, Thoracic - metabolism | Aorta, Thoracic - physiopathology | Cholesterol - metabolism | Plaque, Atherosclerotic | Regional Blood Flow | Atherosclerosis - metabolism | Disease Progression | Mice, Knockout | Aortic Diseases - genetics | Macrophages - metabolism | Phenotype | Animals | ATP Binding Cassette Transporter 1 - deficiency | Endothelial Cells - pathology | Neovascularization, Physiologic | ATP Binding Cassette Transporter 1 - genetics | Index Medicus | HDL | ABC transporters | angiogenesis
Journal Article