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trap1 (119) 119
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hsp90 heat-shock proteins - metabolism (63) 63
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Journal Article
Oncotarget, ISSN 1949-2553, 2017, Volume 8, Issue 13, pp. 20521 - 20522
Journal Article
Oncotarget, ISSN 1949-2553, 05/2016, Volume 7, Issue 22, pp. 32375 - 32393
Metabolic changes are associated with cancer, but whether they are just bystander effects of deregulated oncogenic signaling pathways or characterize early... 
Pentose phosphate pathway | TRAP1 | HCC | NRF2 | Oxidative phosphorylation | PERMEABILITY TRANSITION PORE | GLUTAMINE | MODEL | MITOCHONDRIAL CHAPERONE TRAP1 | CANCER | oxidative phosphorylation | pentose phosphate pathway | CELL BIOLOGY | HEPATOCELLULAR-CARCINOMA | ORIGIN | PATHWAY | WARBURG | Humans | Middle Aged | Rats, Inbred F344 | Gene Expression Regulation, Neoplastic | Hepatocytes - pathology | Male | Precancerous Conditions - metabolism | Carcinoma, Hepatocellular - secondary | Hepatocytes - metabolism | Neoplasm Grading | Transfection | RNA Interference | Time Factors | Cell Transformation, Neoplastic - genetics | Carcinoma, Hepatocellular - genetics | Aged, 80 and over | Female | Liver Neoplasms - pathology | NF-E2-Related Factor 2 - genetics | Precancerous Conditions - pathology | HSP90 Heat-Shock Proteins - genetics | Tumor Cells, Cultured | Energy Metabolism - genetics | Liver Neoplasms - genetics | Oxidative Phosphorylation | Cell Transformation, Neoplastic - metabolism | Precancerous Conditions - genetics | Cellular Reprogramming - drug effects | Gene Expression Regulation, Enzymologic | Animals | NF-E2-Related Factor 2 - metabolism | Liver Neoplasms - metabolism | Glucosephosphate Dehydrogenase - metabolism | Glycolysis | HSP90 Heat-Shock Proteins - metabolism | Aged | Glucosephosphate Dehydrogenase - genetics | Cell Transformation, Neoplastic - pathology | Keratin-19 - metabolism | Pentose Phosphate Pathway | Carcinoma, Hepatocellular - metabolism
Journal Article
The FEBS Journal, ISSN 1742-464X, 06/2014, Volume 281, Issue 12, pp. 2805 - 2819
Journal Article
BMC biology, ISSN 1741-7007, 01/2020, Volume 18, Issue 1, pp. 10 - 23
The molecular chaperone TRAP1, the mitochondrial isoform of cytosolic HSP90, remains poorly understood with respect to its pivotal role in the regulation of... 
HSP90 | TRAP1 | Mitochondria | Oxidative phosphorylation | Molecular chaperone | Glutamine
Journal Article
Journal of Gastroenterology and Hepatology, ISSN 0815-9319, 12/2019, Volume 34, Issue 12, pp. 2118 - 2125
Background and Aim Anti‐tumor necrosis factor (TNF) agents, such as infliximab (IFX), have been increasingly used to induce and maintain disease remission in... 
TRAP1 | Crohn's disease | infliximab | response | BIOMARKERS | INFLAMMATORY-BOWEL-DISEASE | THERAPY | GASTROENTEROLOGY & HEPATOLOGY
Journal Article
International journal of molecular sciences, ISSN 1422-0067, 12/2019, Volume 21, Issue 1, p. 145
Tumor Necrosis Factor Receptor-Associated Protein 1 (TRAP1) is a heat shock protein 90 (HSP90) molecular chaperone overexpressed in 60-70% human colorectal... 
s-nitrosylation | trap1 | colorectal carcinoma | copy number variation | gsnor
Journal Article
by Chen, JF and He, Q and Dai, MH and Kong, W
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ISSN 0006-291X, 06/2019, Volume 515, Issue 1, pp. 64 - 71
Heat shock protein 75 (HSP75, also known as TRAP1) as a member of the Hsp90 molecular chaperone family, has been implicated in the progression of renal... 
OVEREXPRESSION | TRAP1 | Mitochondria | BIOPHYSICS | Heat shock protein 75 | Renal fibrosis | BIOCHEMISTRY & MOLECULAR BIOLOGY | Apoptosis | PROTECTS
Journal Article
Molecular Oncology, ISSN 1574-7891, 12/2014, Volume 8, Issue 8, pp. 1482 - 1494
Journal Article
Cell Death and Differentiation, ISSN 1350-9047, 04/2012, Volume 19, Issue 4, pp. 592 - 602
Journal Article
The Journal of Pathology, ISSN 0022-3417, 09/2017, Volume 243, Issue 1, pp. 123 - 134
Regulation of tumour cell proliferation by molecular chaperones is still a complex issue. Here, the role of the HSP90 molecular chaperone TRAP1 in cell cycle... 
CDK1 | TRAP1 | MAD2 | cell cycle | mitotic entry | PROTEIN | CLASSIFICATION | PROLIFERATION | PATHOLOGY | MITOCHONDRIAL CHAPERONE TRAP1 | INHIBITION | METABOLISM | ONCOLOGY | RESISTANCE | DEGRADATION | CARCINOMA | DEPENDENT KINASES | CDC2 Protein Kinase | Cell Proliferation | Cyclin-Dependent Kinases - metabolism | Mad2 Proteins - metabolism | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Ki-67 Antigen - metabolism | Male | Cyclin B1 - metabolism | Ubiquitination | Transfection | Neoplasms - genetics | RNA Interference | Time Factors | Aged, 80 and over | Adult | Female | Transcription, Genetic | HSP90 Heat-Shock Proteins - genetics | Cyclin-Dependent Kinases - genetics | ATPases Associated with Diverse Cellular Activities | Signal Transduction | Neoplasms - enzymology | G2 Phase Cell Cycle Checkpoints | Mad2 Proteins - genetics | Cell Line, Tumor | HSP90 Heat-Shock Proteins - metabolism | Aged | Proteasome Endopeptidase Complex - metabolism | Neoplasms - pathology | Analysis | Cell cycle | Cell proliferation | Post-transcription | Regulations | Biotechnology | Hsp90 protein | Regulators | Deregulation | Profiling | Transcription | Gene regulation | Colorectal carcinoma | Chaperones | Machinery | Cyclin B1 | Machinery and equipment | Degradation | Proteins | Breast carcinoma | Eukaryotes | Translocation | Lung carcinoma | Tumor cell lines | Gene expression | Transit | Nuclear transport | Quality control | Breast | Biomarkers | Tumors
Journal Article
JOURNAL OF BIOLOGICAL CHEMISTRY, ISSN 0021-9258, 07/2019, Volume 294, Issue 27, pp. 10407 - 10414
The role of mitochondria in cancer continues to be debated, and whether exploitation of mitochondrial functions is a general hallmark of malignancy or a tumor-... 
TRAP1 | CELLS | mitochondria | BIOCHEMISTRY & MOLECULAR BIOLOGY | NEUROBLASTOMA | CANCER | oxidative phosphorylation | invasion | metastasis | GENES | N-MYC | metabolism | EXPRESSION | Myc (c-Myc) | Editors' Picks
Journal Article
Cell Reports, ISSN 2211-1247, 01/2017, Volume 18, Issue 3, pp. 659 - 672
Journal Article