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Molecular Cell, ISSN 1097-2765, 2011, Volume 44, Issue 2, pp. 304 - 316
DEPTOR, an inhibitor of mTORC1 and mTORC2, is degraded via ubiquitin-proteasome pathway by an unknown E3 ubiquitin ligase. Here we report that DEPTOR is a... 
CANCER-CELLS | TARGET | IN-VITRO | COMPLEX | PATHWAY | BIOCHEMISTRY & MOLECULAR BIOLOGY | F-BOX PROTEINS | DEGRADATION | CELL-GROWTH | KAPPA-B | PROMOTES | CELL BIOLOGY | mTOR | SCF E3 ligase | DEPTOR | Autophagy | βTrCP | survival
Journal Article
by Liu, YC
ANNUAL REVIEW OF IMMUNOLOGY, ISSN 0732-0582, 2004, Volume 22, pp. 81 - 127
Ubiquitin (Ub)-protein conjugation represents a novel means of post-transcriptional modification in a proteolysis-dependent or -independent manner. E3 Ub... 
TRCP-MEDIATED UBIQUITINATION | KAPPA-B-KINASE | P105 REQUIRES PHOSPHORYLATION | NEWLY SYNTHESIZED PROTEINS | immunity | IMMUNOLOGY | HECT | lymphocyte | MHC CLASS-I | GROWTH-FACTOR-BETA | INNATE IMMUNE RECOGNITION | TUMOR-SUPPRESSOR FUNCTION | ubiquitination | RING | T-CELL-RECEPTOR | F-BOX PROTEIN
Journal Article
MOLECULAR CELL, ISSN 1097-2765, 03/2013, Volume 49, Issue 6, pp. 1159 - 1166
F-box proteins and DCAF proteins are the substrate binding subunits of the Skp1-Cul1-F-box protein (SCF) and Cul4-RING protein ligase (CRL4) ubiquitin ligase... 
PCNA | PROTEIN | GENE | OTITIS-MEDIA | BETA-TRCP | PATHWAY | BIOCHEMISTRY & MOLECULAR BIOLOGY | UBIQUITYLATION | DEGRADATION | PROTEOLYSIS | IDENTIFICATION | CELL BIOLOGY
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 02/2010, Volume 285, Issue 6, pp. 3794 - 3805
Journal Article
Journal Article
Journal Article
Proceedings of the National Academy of Sciences, ISSN 0027-8424, 05/2014, Volume 111, Issue 19, pp. E1980 - E1989
In epithelial tissues, growth control depends on the maintenance of proper architecture through apicobasal polarity and cell-cell contacts. The Hippo signaling... 
development | signal transduction | Drosophila | MULTIDISCIPLINARY SCIENCES | HIPPO PATHWAY | SCF-BETA-TRCP | MULTIPLE SEQUENCE ALIGNMENT | DROSOPHILA EPITHELIAL-CELLS | SIGNAL-INDUCED UBIQUITINATION | ALPHA UBIQUITINATION | TUMOR-SUPPRESSOR | APICAL-POLARITY PROTEINS | F-BOX PROTEIN | I-KAPPA-B | Biological Sciences | PNAS Plus
Journal Article