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Oncogene, ISSN 0950-9232, 01/2002, Volume 21, Issue 4, pp. 532 - 540
Telomeres allow cells to distinguish natural chromosome ends from damaged DNA. When telomere function is disrupted, a potentially lethal DNA damage response... 
Capping | Senescence | DNA-PK | Genome instability | ATM | Telomere | TRF2 | Apoptosis | P53 | TRF2 protein
Journal Article
Viruses, ISSN 1999-4915, 07/2017, Volume 9, Issue 7, p. 164
Journal Article
Nature, ISSN 0028-0836, 09/2017, Volume 549, Issue 7670, pp. 54 - 59
Nuclear small RNA pathways safeguard genome integrity by establishing transcription-repressing heterochromatin at transposable elements. This inevitably also... 
COMPLEX | SMALL RNAS | CHROMATIN | TBP-LIKE FACTOR | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | POL II | POLYMERASE-II TRANSCRIPTION | TRF2 | MICE LACKING | TFIIA | Multigene Family - genetics | RNA, Small Interfering - genetics | Chromosomal Proteins, Non-Histone - metabolism | Gene Silencing | RNA Polymerase II - metabolism | Drosophila Proteins - metabolism | Drosophila melanogaster - genetics | Promoter Regions, Genetic - genetics | Heterochromatin - chemistry | Animals | Heterochromatin - genetics | Heterochromatin - metabolism | RNA, Small Interfering - biosynthesis | DNA Transposable Elements - genetics | Female | Telomeric Repeat Binding Protein 2 - metabolism | Transcription, Genetic | Transcription Initiation, Genetic | RNA Polymerase II - chemistry | Transcription Factor TFIIA - metabolism | RNA | Genomics | Drosophila | Physiological aspects | Genetic research | Genetic aspects | Genetic transcription | Research | Methods | Transcription factors | Complex formation | Genomes | Biosynthesis | DNA-directed RNA polymerase | Proteins | Heterochromatin | DNA methylation | Clusters | Evolution | Deoxyribonucleic acid--DNA | Initiation complex | Telomere-binding protein | Transposons | Nucleotide sequence | RNA polymerase | Gene expression | Ribonucleic acid--RNA | Loci | Polymerase | TATA-binding protein | Insects | TFIID protein | TRF2 protein | Gene loci | Transcription initiation factor TFIIA | Gonads | RNA polymerase II
Journal Article
Cell Cycle, ISSN 1538-4101, 8/2014, Volume 13, Issue 15, pp. 2469 - 2474
The stability of mammalian telomeres depends upon TRF2, which prevents inappropriate repair and checkpoint activation. By using a plasmid integration assay in... 
shelterin | recombination | Report | telomere | TRF2
Journal Article
Journal Article
Differentiation, ISSN 0301-4681, 07/2018, Volume 102, pp. 27 - 29
Journal Article
Cell, ISSN 0092-8674, 10/2013, Volume 155, Issue 2, pp. 345 - 356
Journal Article
Molecular and Cellular Biochemistry, ISSN 0300-8177, 3/2016, Volume 414, Issue 1, pp. 201 - 208
Telomere uncapping is thought to be the fundamental cause of replicative cellular senescence, but the cellular machineries mediating this process have not been... 
Life Sciences | Biochemistry, general | Senescence | Telomere uncapping | Sp1 | Medical Biochemistry | Oncology | Cardiology | TRF2 ΔBΔM | Nuclear transport | TRF2
Journal Article