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Science (Washington), ISSN 0036-8075, 06/2001, Volume 292, Issue 5524, pp. 2075 - 2077
In yeast, telomere position effect (TPE) results in the reversible silencing of genes near telomeres. Here we demonstrate the presence of TPE in human cells.... 
trichostatin A
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 02/2001, Volume 276, Issue 7, pp. 4539 - 4542
DNA topoisomerase II (topo II) is a ubiquitous nuclear enzyme that is involved in DNA replication, transcription, chromosome segregation, and apoptosis. Here... 
trichostatin A
Journal Article
Cancer Research, ISSN 0008-5472, 02/2001, Volume 61, Issue 4, pp. 1247 - 1249
Remodeling of the chromatin template by inhibition of histone deacetylase (HDAC) activities represents a major goal for transcriptional therapy in neoplastic... 
trichostatin A
Journal Article
02/2013
Background: Epigenetic reprogramming of differentiated cells can modify somatic cells into pluripotential state. Pluripotency can be induced in somatic cells... 
Reprogramming | 5-Aza-Deoxycytidine | Embryonic stem cell | Trichostatin A | Cell free extract
Web Resource
Biology of Reproduction, ISSN 0006-3363, 06/2001, Volume 64, Issue 6, pp. 1713 - 1721
Superimposed on the activation of the embryonic genome in the preimplantation mouse embryo is the formation of a transcriptionally repressive state during the... 
trichostatin A
Journal Article
Tuberculosis, ISSN 1472-9792, 09/2019, Volume 118, p. 101861
Histone deacetylase inhibitors (HDACi), a novel class of anti-cancer drug, have been recently reported to suppress host immunity and increase susceptibility to... 
Trichostatin A | Mycobacterium tuberculosis | Susceptibility | HDACi | Autophagy
Journal Article
Developmental dynamics : an official publication of the American Association of Anatomists, ISSN 1058-8388, 11/2015, Volume 244, Issue 11, pp. 1404 - 1414
Journal Article
Biochimie, ISSN 0300-9084, 08/2017, Volume 139, pp. 56 - 73
The use of histone acetyl-transferase inhibitors such as trichostatin A (TSA) for epigenetic transformation of mesenchymal stem cells (MSCs), whose nuclei will... 
Transcriptome | Trichostatin A | Mesenchymal stem cells | Pig
Journal Article
Asian Pacific Journal of Cancer Prevention, ISSN 1513-7368, 12/2017, Volume 18, Issue 12, pp. 3445 - 3450
Epigenetic changes such as DNA methylation and histone acetylation play important roles in determining gene expression. Hypermethylation of CpG islands of the... 
Hepatocellular carcinoma | Genistein | Trichostatin A | trichostatin A | hepatocellular carcinoma
Journal Article
Frontiers in Microbiology, ISSN 1664-302X, 10/2019, Volume 10
Histone deacetylase inhibitor (HDACi) has been used in the treatment of neurodegenerative or autoimmune diseases. Angiostrongyliasis cantonensis caused by... 
trichostatin A | inflammation | Angiostrongylus cantonensis | cognitive impairments | eosinophilic meningitis | HDAC
Journal Article
Cell, ISSN 0092-8674, 06/2013, Volume 153, Issue 6, pp. 1228 - 1238
Reprogramming somatic cells into pluripotent embryonic stem cells (ESCs) by somatic cell nuclear transfer (SCNT) has been envisioned as an approach for... 
NUMBER | ACTIVATION | CLONING | BIOCHEMISTRY & MOLECULAR BIOLOGY | MOUSE | PREIMPLANTATION DEVELOPMENT | MG132 | IVF | OOCYTES | TRICHOSTATIN-A | PRIMATES | CELL BIOLOGY | Gene expression | Embryonic stem cells | Chromosomes | Genomics
Journal Article
Oncotarget, ISSN 1949-2553, 01/2019, Volume 10, Issue 3, pp. 404 - 414
Melanoma, one of the most aggressive neoplasms, is characterized by rapid cell proliferation. Transducin-like Enhancer of Split (TLE) is an important regulator... 
HDAC inhibitors | Trichostatin A | Transcriptional co-repressor | Malignant melanoma
Journal Article
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ISSN 0006-291X, 02/2006, Volume 340, Issue 1, pp. 183 - 189
The low success rate of animal cloning by somatic cell nuclear transfer (SCNT) is believed to be associated with epigenetic errors including abnormal DNA... 
METHYLATION | trichostatin A | BIOCHEMISTRY & MOLECULAR BIOLOGY | NT-ES | EMBRYONIC STEM-CELL | full term development | LINES | mouse | BIOPHYSICS | CLONED MICE | GENE-EXPRESSION | nuclear transfer | DONOR CELLS | HISTONE DEACETYLASE
Journal Article
Frontiers in pharmacology, ISSN 1663-9812, 2018, Volume 9, p. 1434
[This corrects the article DOI: 10.3389/fphar.2017.00223.]. 
trichostatin-A | survivin | wound healing | cytokines | scarring | haze
Journal Article
Theriogenology, ISSN 0093-691X, 11/2013, Volume 80, Issue 8, pp. 878 - 886
It has been reported that buffalo ( Bubalus bubalis) embryos reconstructed by somatic cell nucleus transfer (SCNT) can develop to the full term of gestation... 
Embryo developmental competence | Nucleus reprogramming | Histone acetylation | Trichostatin A
Journal Article
Cell Death and Disease, 01/2011, Volume 2, Issue 1, p. e117
  Histone deacetylase inhibitors (HDACIs) have shown promising anti-tumor effects for a variety of malignancies, however, many tumors are reportedly resistant... 
PP1 | AKT | Trichostatin A | Tubulin | C6-ceramide | Histone deacetylase inhibitors
Journal Article
Advanced biomedical research, ISSN 2277-9175, 2019, Volume 8, Issue 1, pp. 52 - 52
Cancer initiation and progression depends on genetic and epigenetic alterations such as DNA methylation and histone modifications. Hypermethylation and... 
5-Aza-2'-deoxycytidine | cancer | valproic acid | trichostatin A
Journal Article
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, ISSN 1046-6673, 01/2007, Volume 18, Issue 1, pp. 58 - 65
Histone acetylation plays an important role in regulating gene expressions by modulating chromatin structure. Histone deacetylase (HDAC) inhibitors have been... 
FIBROSIS | APOPTOSIS | GROWTH-FACTOR-BETA | UNILATERAL URETERAL OBSTRUCTION | CANCER CELLS | MECHANISM | DISEASE | MESANGIAL CELLS | UROLOGY & NEPHROLOGY | FIBROGENESIS | TRICHOSTATIN-A
Journal Article
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