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trifluoromethyl-beta-diketones (19) 19
chemistry, organic (17) 17
derivatives (12) 12
chemistry, inorganic & nuclear (10) 10
inhibitors (10) 10
dehydration (7) 7
pyrazoles (7) 7
antibacterial activity (6) 6
fluorine (6) 6
hydrazines (6) 6
hydroxylamine (6) 6
chemistry, medicinal (5) 5
heterocycles (5) 5
trifluoromethyl-beta-diketone (5) 5
anti-inflammatory activity (4) 4
biological evaluation (4) 4
pyrazole (4) 4
regioselective synthesis (4) 4
regioselectivity (4) 4
trifluoromethyl-β-diketone (4) 4
1,3-diketones (3) 3
agents (3) 3
antibacterial agents (3) 3
antifungal activity (3) 3
celecoxib (3) 3
cox-2 inhibitors (3) 3
design (3) 3
haloacetylated enol ethers (3) 3
hydrazine (3) 3
molecular structure (3) 3
nmr (3) 3
potent (3) 3
1,5-diarylpyrazole class (2) 2
19f nmr (2) 2
3-trifluoromethylpyrazoles (2) 2
5-trifluoromethylpyrazoles (2) 2
analogs (2) 2
analysis (2) 2
anti-bacterial agents - chemical synthesis (2) 2
anti-bacterial agents - chemistry (2) 2
anti-bacterial agents - pharmacology (2) 2
antiinfectives and antibacterials (2) 2
aryl (2) 2
bacteria (2) 2
biochemistry, general (2) 2
biomedicine (2) 2
c-13 (2) 2
c-13 nmr (2) 2
cell biology (2) 2
chemistry, multidisciplinary (2) 2
convenient synthesis (2) 2
drugs (2) 2
f nmr (2) 2
f-19 nmr (2) 2
facile synthesis (2) 2
factor xa (2) 2
gram-negative bacteria - drug effects (2) 2
gram-positive bacteria - drug effects (2) 2
highly potent (2) 2
identification (2) 2
inflammation (2) 2
isoxazoles (2) 2
ketones (2) 2
microbial sensitivity tests (2) 2
pharmacology/toxicology (2) 2
pyrazole derivatives (2) 2
pyridine (2) 2
synthesis (2) 2
trifluoromethyl-β-diketones (2) 2
1,2,4-triazolo[4,3-a]quinoxaline (1) 1
1,3-diketone (1) 1
1,5-diarylpyrazoles (1) 1
1--2-arylazo-4,4,4-trifluorobutane-1,3-diones (1) 1
123066-63-7 (1) 1
128228-96-6 (1) 1
134947-26-5 (1) 1
153628-52-5 (1) 1
153628-54-7 pyrazoles (1) 1
1629-78-3 (1) 1
1632-83-3 (1) 1
19959-90-1 (1) 1
2,4-disubstituted thiazoles (1) 1
2--4- (1) 1
2-h/methyl-3-phenyl-5-alkyl/aryl/heteroaryl-7-trifluoromethylpyrazolo[1,5-a]pyrimidines (1) 1
2-h/methyl-3-phenyl-5-alkyl/aryl/heteroaryl-7-trifluoromethylpyrazolo[1,5-alpha]pyrimidines (1) 1
2-hydrazino-3-phenylquinoxaline (1) 1
2-hydrazino-4,6-dimethylpyrimidine (1) 1
2-hydrazinobenzothiazole (1) 1
214854-86-1 (1) 1
229317-78-6 (1) 1
229317-79-7 (1) 1
229317-80-0 (1) 1
229317-81-1 (1) 1
229317-82-2 (1) 1
229317-83-3 pyrazoles (1) 1
229317-84-4 (1) 1
229317-85-5 pyrazoles (1) 1
3+2 cyclocondensation (1) 1
3--4-arylazo-5-hydroxy-5-trifluoromethyl-delta-isoxazolines (1) 1
3--4-arylazo-5-trifluoromethylisoxazoles (1) 1
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Medicinal Chemistry Research, ISSN 1054-2523, 11/2012, Volume 21, Issue 11, pp. 3757 - 3766
A novel series of heteroaromatic analogues of known anti-inflammatory (AI) drug celecoxib replacing the benzenesulfonamide moiety with... 
Biochemistry, general | Biomedicine | NSAID | Anti-inflammatory activity | Inflammation | 1,5-Diarylpyrazoles | Pharmacology/Toxicology | Benzothiazolesulfonamide | Cell Biology | CHEMISTRY, MEDICINAL | DEHYDRATION | DRUGS | REGIOSELECTIVE SYNTHESIS | BIOLOGICAL EVALUATION | TRIFLUOROMETHYL-BETA-DIKETONES | ARYL | INHIBITORS | DERIVATIVES
Journal Article
European Journal of Organic Chemistry, ISSN 1434-193X, 08/2018, Volume 2018, Issue 27-28, pp. 3750 - 3755
Gold‐ and silver‐catalysed reactions of trifluoromethylated ynones with aryl (alkyl) hydrazines were investigated. The use of (THD‐Dipp)AuOTf and AgOTf... 
Silver | Nitrogen heterocycles | Regioselectivity | Fluorine | Pyrazoles | Fluorinated compounds | HYDRAZONES | CHEMISTRY, ORGANIC | 3+2 CYCLOCONDENSATION | ALKYNES | SOLVENT | PYRAZOLE | INTERMOLECULAR HYDROAMINATION | TRIFLUOROMETHYL-BETA-DIKETONES | COX-2 inhibitors
Journal Article
European journal of medicinal chemistry, ISSN 0223-5234, 2013, Volume 62, pp. 508 - 514
Journal Article
Journal of Fluorine Chemistry, ISSN 0022-1139, 12/2015, Volume 180, pp. 55 - 97
The review summarizes the synthetic approaches of fluorinated isoxazolines and isoxazoles. Biological significance, mechanistic aspects and their NMR spectral... 
Trifluoromethyl | Isoxazole | NMR | Synthetic routes | Fluorine | Isoxazoline | HYDROXYLAMINE | PYRAZOLES | NATURAL-PRODUCTS | CHEMISTRY, ORGANIC | N-NUCLEOPHILES | CHEMISTRY, INORGANIC & NUCLEAR | MEDICINAL CHEMISTRY | SUBSTITUTED HETEROCYCLES | TRIFLUOROMETHYL-BETA-DIKETONES | INHIBITORS | DERIVATIVES | HALOACETYLATED ENOL ETHERS
Journal Article
Synlett, ISSN 0936-5214, 09/2017, Volume 28, Issue 15, pp. 2018 - 2023
Journal Article
INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, ISSN 0971-1627, 10/2017, Volume 27, Issue 4, pp. 439 - 442
The reaction of 2-hydrazino-4,6-dimethylpyrimidine with trifluoromethyl-beta-diketones has been studied in different reaction conditions (neutral as well as... 
3/5Trifluoromethylpyrazoles | Regioselectivity | BIOLOGICAL EVALUATION | CHEMISTRY, ORGANIC | Trifluoromethyl-beta-diketones | 5-Hydroxy-5 trifluoromethylpyrazolines | DERIVATIVES | 2-Hydrazino-4,6-dimethylpyrimidine
Journal Article
Journal of Fluorine Chemistry, ISSN 0022-1139, 2010, Volume 131, Issue 3, pp. 426 - 432
Bromodifluoromethyl substituted β-diketones reacted with aryl hydrazine derivatives or hydroxylamine hydrochloride affording corresponding bromodifluoromethyl... 
Isoxazoles | Synthesis | Bromodifluoromethyl | Regioselectivity | Pyrazoles | DESIGN | HETEROCYCLES | CHEMISTRY, ORGANIC | TRIFLUOROMETHYL-BETA-DIKETONES | INHIBITORS | CHEMISTRY, INORGANIC & NUCLEAR | Fine chemicals | Hydroxides
Journal Article
ChemistrySelect, ISSN 2365-6549, 11/2016, Volume 1, Issue 18, pp. 5990 - 5994
In this article we present the unprecedented preparation of 4,7‐dihydro‐1H‐pyrazolo[3,4‐b]pyridine‐5‐nitriles and pyrazolo[3,4‐b]pyridine‐5‐nitrile derivatives... 
Pyrazolo[3,4-b]pyridine- 5-nitriles | 5-Aminopyrazoles | 4,7-Dihydro-1H-pyrazolo[3,4-b]pyridine-5-nitriles | 3-aryl-3-oxopropanonitriles | Domino assemblage | HYDROXYLAMINE | PYRAZOLE DERIVATIVES | ONE-POT | ANTIMICROBIAL AGENTS | ALPHA | 3-AMINOPYRAZOLE INHIBITORS | ANTITUMOR | CHEMISTRY, MULTIDISCIPLINARY | Pyrazolo[3,4-b] pyridine-5-nitriles | TRIFLUOROMETHYL-BETA-DIKETONES | ARYL
Journal Article
International Journal of Chemical Kinetics, ISSN 0538-8066, 07/2008, Volume 40, Issue 7, pp. 370 - 383
Reaction kinetics for the condensation of 1,3‐diketones 1a–o with selected arylhydrazines (aryl = Ph, 4‐NO2Ph, 4‐CH3OPh, and 2,4‐diNO2Ph) was studied using 19F... 
CATALYSIS | C-13 | HETEROCYCLES | CHEMISTRY, PHYSICAL | HYDRAZINES | TRIFLUOROMETHYL-BETA-DIKETONES | INHIBITORS | REGIOSELECTIVITY | IDENTIFICATION | DERIVATIVES | CYCLIZATION
Journal Article
Journal of Fluorine Chemistry, ISSN 0022-1139, 2009, Volume 130, Issue 10, pp. 886 - 893
Journal Article
Heterocycles, ISSN 0385-5414, 01/2004, Volume 63, Issue 1, pp. 145 - 173
Reaction of several heteroarylhydrazines with beta-diketones has been incorrectly reported to generate triazepines or diazepines. It has now been firmly... 
CONVENIENT SYNTHESIS | HANTZSCH THIAZOLE SYNTHESIS | DEHYDROACETIC ACID | pyrazole | CHEMISTRY, ORGANIC | HYDRAZINES | hydrazine | diazepine | ETHYL ACETOACETATE | PRODUCTS | SPECTROSCOPY H-1 | triazepine | TRIFLUOROMETHYL-BETA-DIKETONES | C-13 NMR | DERIVATIVES | 1,3-diketone
Journal Article
Journal of Fluorine Chemistry, ISSN 0022-1139, 1999, Volume 94, Issue 2, pp. 199 - 203
Journal Article
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