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CURRENT OPINION IN NEUROLOGY, ISSN 1350-7540, 06/2019, Volume 32, Issue 3, pp. 405 - 412
Purpose of review Migraine is a common, highly disabling disorder. Its treatment involves acute and preventive therapy. Many of available preventive... 
NOCICEPTIVE PATHWAYS | pain | CANNABIDIOL | ANANDAMIDE | NEUROSCIENCES | CLINICAL NEUROLOGY | FEMALE | ALLOSTERIC MODULATOR | CB1 | endogenous and exogenous cannabinoids | HEADACHE | RECEPTOR ACTIVATION | trigeminovascular system | CANNABINOIDS | Care and treatment | Cellular signal transduction | Research | Migraine | Endocannabinoids
Journal Article
Neuron, ISSN 0896-6273, 03/2018, Volume 97, Issue 5, pp. 1004 - 1021
Journal Article
Journal of Cerebral Blood Flow & Metabolism, ISSN 0271-678X, 4/2019, Volume 39, Issue 4, pp. 704 - 717
Migraine abortives likely target both peripheral-dural and central trigeminovascular mechanisms in mediating their therapeutic effects. However, in preclinical... 
preventives | peripheral | central | trigeminovascular system | Migraine | PLASMA EXTRAVASATION | TRIGEMINAL NEURONS | GENE-RELATED PEPTIDE | CORTICAL SPREADING DEPRESSION | BRAIN-STEM | NEUROSCIENCES | RECEPTOR ANTAGONIST | SUPERIOR SAGITTAL SINUS | CERVICAL SPINAL-CORD | NOCICEPTIVE TRANSMISSION | ENDOCRINOLOGY & METABOLISM | DOUBLE-BLIND | HEMATOLOGY
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 12/2013, Volume 170, Issue 7, pp. 1293 - 1307
The neuropeptide calcitonin gene‐related peptide (CGRP) is reported to play an important role in migraine. It is expressed throughout the trigeminovascular... 
trigeminal ganglia | calcitonin gene‐related peptide | migraine | Amylin | G‐protein coupled receptor | GPCR | CGRP | trigeminovascular system | G-protein coupled receptor | calcitonin gene-related peptide | AMYLOID POLYPEPTIDE AMYLIN | SPINAL TRIGEMINAL NUCLEUS | GENE-RELATED-PEPTIDE | CYCLIC-AMP FORMATION | CALCITONIN-RECEPTOR | SK-N-MC | PHARMACOLOGY & PHARMACY | CENTRAL-NERVOUS-SYSTEM | SMOOTH-MUSCLE-CELLS | SUBSTANCE-P | ACTIVITY-MODIFYING PROTEIN-1 | Central Nervous System Agents - therapeutic use | Trigeminal Nerve - metabolism | Trigeminal Nucleus, Spinal - metabolism | Receptors, Calcitonin - metabolism | Humans | Vasodilation | Migraine Disorders - metabolism | Calcitonin Gene-Related Peptide - antagonists & inhibitors | Migraine Disorders - physiopathology | Trigeminal Nerve - physiopathology | Receptors, Islet Amyloid Polypeptide - metabolism | Calcitonin Gene-Related Peptide - metabolism | Trigeminal Nuclei - metabolism | Trigeminal Nuclei - physiopathology | Signal Transduction | Receptor Activity-Modifying Protein 1 - metabolism | Trigeminal Ganglion - metabolism | Adrenomedullin - metabolism | Migraine Disorders - drug therapy | Trigeminal Nerve - drug effects | Animals | Trigeminal Nuclei - drug effects | Cerebral Arteries - innervation | Trigeminal Ganglion - physiopathology | Trigeminal Nucleus, Spinal - physiopathology | Peptides | Physiological aspects | Migraine | Signal transduction | Themed Section | Neuropeptides
Journal Article
Journal Article
Molecular Pain, ISSN 1744-8069, 01/2019, Volume 15, p. 1744806918820452
Migraine is the seventh most disabling disorder globally, with prevalence of 11.7% worldwide. One of the prevailing mechanisms is the activation of the... 
electrical stimulation | calcitonin gene-related peptide | pituitary adenylate cyclase-activating peptide | Migraine | PAC1 receptor | CYCLASE-ACTIVATING POLYPEPTIDE | CUTANEOUS ALLODYNIA | VASOACTIVE-INTESTINAL-PEPTIDE | NEUROSCIENCES | MENINGEAL | PLASMA | INCREASE | VIP | EXPRESSION | BURDEN | BLOOD
Journal Article
Annual Review of Pharmacology and Toxicology, ISSN 0362-1642, 1/2015, Volume 55, Issue 1, pp. 533 - 552
Migraine is a neurological disorder that manifests as a debilitating headache associated with altered sensory perception. The neuropeptide calcitonin... 
neuromodulation | sensitization | trigeminovasculature | photophobia | neuropeptide | Sensitization | Trigeminovasculature | Neuromodulation | Neuropeptide | Photophobia | TRIGEMINAL GANGLION | TRIGEMINOVASCULAR SYSTEM | CORTICAL SPREADING DEPRESSION | MENINGEAL NOCICEPTORS | RANDOMIZED CONTROLLED-TRIAL | INTERNATIONAL UNION | RECEPTOR ANTAGONIST BIBN4096BS | DOUBLE-BLIND | PHARMACOLOGY & PHARMACY | TOXICOLOGY | SUBSTANCE-P | ACTIVITY-MODIFYING PROTEIN-1 | Neural Pathways - drug effects | Humans | Epistasis, Genetic - drug effects | Antibodies, Monoclonal - therapeutic use | Receptors, Calcitonin Gene-Related Peptide - metabolism | Migraine Disorders - metabolism | Pain Perception - drug effects | Calcitonin Gene-Related Peptide - antagonists & inhibitors | Drug Design | Migraine Disorders - physiopathology | Pain Threshold - drug effects | Epigenesis, Genetic - drug effects | Neural Pathways - physiopathology | Calcitonin Gene-Related Peptide - metabolism | Molecular Targeted Therapy - methods | Analgesics - therapeutic use | Receptors, Calcitonin Gene-Related Peptide - antagonists & inhibitors | Calcitonin Gene-Related Peptide - genetics | Migraine Disorders - drug therapy | Animals | Migraine Disorders - genetics | Signal Transduction - drug effects | Receptors, Calcitonin Gene-Related Peptide - immunology | Neural Pathways - metabolism | Calcitonin Gene-Related Peptide - immunology | Receptors, Calcitonin Gene-Related Peptide - genetics | Index Medicus
Journal Article