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trioxane dimers (87) 87
chemistry, medicinal (53) 53
humans (53) 53
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dimers (11) 11
peroxides (11) 11
trioxanes (11) 11
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Journal Article
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 04/2018, Volume 150, pp. 829 - 840
Artemisinin is a potential anticancer agent with an interesting trioxane sesquiterpene structure. In order to improve the biological activity and metabolic... 
Linker modification | Anti-proliferation | Ring-contracted artemisinin | Dimers | Anticancer activity | CHEMISTRY, MEDICINAL | DRUG DISCOVERY | ANTIMALARIAL | NATURAL-PRODUCT HYBRIDS | IN-VITRO | HIGH-STABILITY | PLASMODIUM-FALCIPARUM | LEUKEMIA-CELLS | TRIOXANE DIMERS | DERIVATIVES | CANCER CELL-LINES | Care and treatment | Nuclear nonproliferation | Liver | Cancer
Journal Article
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 02/2004, Volume 47, Issue 5, pp. 1290 - 1298
Four series of C-10 non-acetal dimers were prepared from key trioxane alcohol 10beta-(2-hydroxyethyl)deoxoartemisinin (9b). All of the dimers prepared... 
HL60 CELLS | APOPTOSIS | IN-VITRO | CHEMISTRY, MEDICINAL | TRANSFERRIN-RECEPTOR | ANTICANCER | ANALOGS | QINGHAOSU ARTEMISININ | TRIOXANE DIMERS | DERIVATIVES | CYTOTOXICITY
Journal Article
PLoS ONE, ISSN 1932-6203, 2010, Volume 5, Issue 4, p. e10370
Journal Article
Synthesis, ISSN 0039-7881, 10/2011, Volume 2011, Issue 19, pp. 3173 - 3179
Abstract A series of C-10 acetal triazolylartemisinin dimers were prepared via the Huisgen 1,3-dipolar cylcoaddition of artemisinin-derived terminal alkynes... 
paper | artemisinin | Artemisia annua | artemisinin dimer | antimalarial | 1,2,3-triazole | ASPERGILLUS-NIGER | TRANSFORMATION | ANGIOGENESIS | EFFICACY | CLICK CHEMISTRY | CHEMISTRY, ORGANIC | INHIBITION | ANTIMALARIAL ARTESUNATE | TRIOXANE DIMERS | DERIVATIVES | CYTOTOXICITY
Journal Article