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JOURNAL OF BIOLOGICAL CHEMISTRY, ISSN 0021-9258, 06/2019, Volume 294, Issue 24, pp. 9489 - 9502
Iron-sulfur clusters are essential cofactors of proteins. In eukaryotes, iron-sulfur cluster biogenesis requires a mitochondrial iron-sulfur cluster machinery... 
CFD1-NBP35 COMPLEX | FRATAXIN | tRNA thiolation | PROTEIN | mitochondria | BIOCHEMISTRY & MOLECULAR BIOLOGY | MATURATION | yeast | cytoplasm | BIOGENESIS | metal cofactor | iron | sulfur | iron-sulfur protein | COMPONENT | FE4S4 CLUSTER | ABC transporter | export | REVEALS | SCAFFOLD
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2016, Volume 113, Issue 45, pp. 12703 - 12708
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 07/2017, Volume 114, Issue 28, p. 7355
Sulfur is present in several nucleosides within tRNAs. In particular, thiolation of the universally conserved methyl-uridine at position 54 stabilizes tRNAs... 
Sulfide | Temperature requirements | Oxygen | tRNA | AMP | Archaea | Hyperthermophilic archaea | Iron | High temperature | Ribonucleic acid--RNA | Thermophilic bacteria | Sulfides | Spectrum analysis | Clusters | Uridine | Bacteria | Catalysis | Sulfur | ATP | Binding sites | Crystal structure | Carbonyls
Journal Article
FEBS LETTERS, ISSN 0014-5793, 04/2015, Volume 589, Issue 8, pp. 904 - 909
The ubiquitin-like protein Urm1 from budding yeast and its E1-like activator Uba4 have dual roles in protein urmylation and tRNA thiolation pathways. To study... 
tRNA thiolation | URM1 | BIOCHEMISTRY & MOLECULAR BIOLOGY | WOBBLE URIDINE MODIFICATION | CARRIER | CELL BIOLOGY | PROTEIN CONJUGATION | SULFUR TRANSFER | NUCLEOSIDE MCMSU | THIO-MODIFICATION | BIOPHYSICS | Urm1 (hURM1) | PATHWAY | BIOSYNTHESIS | REQUIRES | Ubiquitin-like urmylation | Saccharomyces cerevisiae | Uba4 (hUBA4/MOCS3)
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2014, Volume 9, Issue 6, p. e99104
Journal Article
Journal Article
Cell Chemical Biology, ISSN 2451-9456, 06/2018, Volume 25, Issue 6, pp. 738 - 748.e3
In eukaryotes, mitochondria have been hypothesized to generate sulfur species required for tRNA thiolation in the cytosol, although no direct evidence thus far... 
cysteine desulfurase | tRNA thiolation | cytosol | mitochondria | sulfur intermediates | iron-sulfur protein | Isu1/2 scaffolds | ABC transporter | export | yeast | CLUSTER BIOGENESIS | ABC TRANSPORTER | YEAST | THIO-MODIFICATION | IRON HOMEOSTASIS | NFS1P | BIOCHEMISTRY & MOLECULAR BIOLOGY | INTACT MITOCHONDRIA | PROTEIN BIOGENESIS | MATURATION | TRANSLATION
Journal Article
Microbial cell (Graz, Austria), ISSN 2311-2638, 10/2016, Volume 3, Issue 11, pp. 554 - 564
Urm1 is a unique dual-function member of the ubiquitin protein family and conserved from yeast to man. It acts both as a protein modifier in ubiquitin-like... 
ubiquitin-like modifier Urm1 | tRNA thiolation | tRNase zymocin | sulfur transferase Tum1 | Saccharomyces cerevisiae | protein urmylation | E1-like enzyme Uba4
Journal Article