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11/2009
Ion channels are proteins that facilitate ion diffusion across cell membrane. Nevertheless, various groups of ion channels can act as surface receptors and... 
Protein Interactions | TRPM7 | 0307 | 0317
Dissertation
11/2011
Transient Receptor Potential ‘Melastatin’ 7 (TRPM7) is a ubiquitously expressed, non-selective divalent cation channel implicated in diverse cellular functions... 
biology | cofilin | cytoskeleton | neuron | TRPM7 | stroke | 0317
Dissertation
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 02/2016, Volume 470, Issue 2, pp. 362 - 367
Zinc toxicity is one of the key factors responsible for the neuronal injuries associated with various neurological conditions. Zinc accumulation in some cells... 
Neurotoxicity | Stress hormone | TRPM7 channel
Journal Article
11/2013
Transient Receptor Potential Melastatin 7 (TRPM7) is a ubiquitously expressed divalent cation channel implicated as a key regulator of neuronal cell death in... 
oxygen glucose deprivation | 0379 | anoxia | TRPM7 | slingshot phosphatase
Dissertation
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 08/2017, Volume 114, Issue 34, pp. E7092 - E7100
Ion channels are proteins that span the cell’s membrane and affect the rapid transfer of ions. Kinases are proteins that transfer a phosphate from ATP to... 
PRMT5 | TRPM7 | Ion channel | Kinase | TRPM6 | Biological Sciences | kinase | PNAS Plus | ion channel
Journal Article
Journal Article
CELLULAR SIGNALLING, ISSN 0898-6568, 11/2012, Volume 24, Issue 11, pp. 2070 - 2075
PLC-isozymes are central elements of cellular signaling downstream of numerous receptors. PLC gamma 2 is a pivotal component of B cell receptor (BCR)... 
Ser | KINASE-ACTIVITY | SECONDARY HYPOCALCEMIA | ACTIVATION | DOMAIN | PROTEIN | C-GAMMA-2 | Hypomagnesia | Thr phosphorylation TRPM7 | PLC gamma 2 | CELL BIOLOGY | MG2+ HOMEOSTASIS | B-CELL | B Cell Receptor signaling | TRPM7 CHANNEL | AUTOPHOSPHORYLATION
Journal Article
PLOS GENETICS, ISSN 1553-7404, 04/2014, Volume 10, Issue 4
Intellectual disability and seizures are frequently associated with hypomagnesemia and have an important genetic component. However, to find the genetic origin... 
EPITHELIAL CA2 | CHANNEL FUNCTIONS | ZEBRAFISH | TRANSPORTER | MEMBRANE | GENETICS & HEREDITY | TRPM7 | GENERATION | EXPRESSION | BEHAVIORS | HYPOMAGNESEMIA
Journal Article
Neurochemistry International, ISSN 0197-0186, 11/2015, Volume 90, pp. 107 - 113
Searching for effective pharmacological agents for traumatic brain injury (TBI) treatment has largely been unsuccessful. The transient receptor potential... 
TRPM7 | Traumatic brain injury | Calcium homeostasis | nNOS | BRAIN-INJURY | TRPC1 | BIOCHEMISTRY & MOLECULAR BIOLOGY | DOWN-REGULATION | ISCHEMIA | DEATH | MECHANISMS | NEUROSCIENCES | IN-VITRO MODEL | TRPM7 CHANNELS
Journal Article
Oncotarget, ISSN 1949-2553, 2017, Volume 8, Issue 66, pp. 109985 - 109999
Neuroblastoma (NB) is the most common extra-cranial pediatric solid tumor. High-risk NB is difficult to treat due to the lack of response to current therapies... 
TRPM7 | Neuroblastoma | Calcium | FTY720 | Channel | SURVIVAL | calcium | PROTEIN | KINASE | MITOCHONDRIA | neuroblastoma | channel | SCLEROSIS | CELL-DEATH | PERMEABILITY TRANSITION | CELL BIOLOGY | ION-CHANNEL | SPHINGOSINE | TRPM7 CHANNELS
Journal Article
BIOCHEMICAL JOURNAL, ISSN 0264-6021, 10/2011, Volume 439, Issue 1, pp. 129 - 139
SLC41A1 (solute carrier family 41, member A1) is a recently described vertebrate member of the MgtE family of Mg2+ transporters. Although MgtE transporters are... 
HOMEOSTASIS | membrane | transient receptor potential melastatin 7 (TRPM7) | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRAFFICKING | magnesium | member A1 (SLC41A1) | MgtE | INTERNALIZATION | CHANNEL | solute carrier 41 | transporter | TRPM7 | PROTEINS | EXPRESSION
Journal Article
MOLECULAR IMMUNOLOGY, ISSN 0161-5890, 11/2018, Volume 103, pp. 173 - 181
Background: TRPM7 in mast cells plays a key role in asthma. However, the effect of TRPM7 on TGF-beta 1-induced airway smooth muscle cell (ASMC) proliferation... 
ENTRY | TGF-beta 1 | BIOCHEMISTRY & MOLECULAR BIOLOGY | TGF beta R/SMAD3 | IMMUNOLOGY | Airway smooth muscle cells | Asthma | GROWTH-FACTOR-BETA | HEPATIC STELLATE CELLS | PATHWAY | TRPM7 | MICE | TRPM7 CHANNEL | TRIPTOLIDE
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2018, Volume 115, Issue 44, pp. E10370 - E10378
At fertilization, repetitive calcium signals are induced in mammalian eggs that are essential for activating embryo development. These signals are supported by... 
TRPM7 | Calcium | Fertilization | Oocyte | 3.2 | Biological Sciences | oocyte | calcium | PNAS Plus | fertilization | CaV3.2
Journal Article
Journal Article
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 2019, Volume 513, Issue 1, pp. 159 - 165
The magnesium transporters TRPM7 and MagT1 are overexpressed in osteoblastogenesis. We have shown that silencing either TRPM7 or MagT1 accelerates the... 
MagT1 | TRPM7 | Autophagy | Osteogenic differentiation | Mesenchymal stem cells | MAGNESIUM | BIOPHYSICS | BIOCHEMISTRY & MOLECULAR BIOLOGY | BIOLOGY | Growth | Stem cells
Journal Article
Molecular Immunology, ISSN 0161-5890, 11/2018, Volume 103, pp. 173 - 181
TRPM7 in mast cells plays a key role in asthma. However, the effect of TRPM7 on TGF-β1-induced airway smooth muscle cell (ASMC) proliferation remains unclear.... 
TGF-β1 | TRPM7 | TGFβR/SMAD3 | Airway smooth muscle cells | Asthma
Journal Article
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