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Journal Article
Nucleic Acids Research, ISSN 0305-1048, 07/2018, Volume 46, Issue W1, pp. W368 - W373
Abstract MOLEonline is an interactive, web-based application for the detection and characterization of channels (pores and tunnels) within biomacromolecular... 
ACID | DATABASE | STRUCTURAL BASIS | ENZYMES | BIOCHEMISTRY & MOLECULAR BIOLOGY | PROTEIN DATA-BANK | TRPML1 CHANNEL | Web Server Issue
Journal Article
Ecotoxicology and Environmental Safety, ISSN 0147-6513, 04/2020, Volume 192, p. 110255
Tetrabromobisphenol A (TBBPA) and its derivatives are the common flame-retardants that may increase the risk of development of many types of cancers, including... 
TRPML1 | Liver cancer | Lysosome exocytosis | Migration and invasion | TBBPA
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 04/2015, Volume 35, Issue 17, pp. 6801 - 6812
Journal Article
Autophagy, ISSN 1554-8627, 01/2020, Volume 16, Issue 1, pp. 169 - 170
Inhibition of host macroautophagy/autophagy is one of the strategies used by several intracellular pathogens, including H. pylori, to escape killing. Here we... 
TRPML1 | xenophagy | VacA | autophagosomes | H. pylori | lysosomes | Autophagy | pylori | CELL BIOLOGY
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 05/2017, Volume 292, Issue 20, pp. 8424 - 8435
Intracellular lysosomal membrane trafficking, including fusion and fission, is crucial for cellular homeostasis and normal cell function. Both fusion and... 
MEMBRANE-FUSION | MUCOLIPIDOSIS | NAADP | STORAGE DISEASES | PATHWAY | BIOCHEMISTRY & MOLECULAR BIOLOGY | CALCIUM-RELEASE | ION-CHANNEL | TRAFFICKING | 2-PORE CHANNELS | LUMINAL PH | calcium channel | calcium | lysosomal Ca2 | calmodulin (CaM) | lysosome | trpml1 | membrane trafficking | Cell Biology
Journal Article
Nature Cell Biology, ISSN 1465-7392, 03/2016, Volume 18, Issue 4, pp. 404 - 417
Journal Article
Journal of Alzheimer's disease : JAD, ISSN 1387-2877, 2019, Volume 67, Issue 1, pp. 393 - 410
Cholesterol dyshomeostasis has been linked to the pathogenesis of sporadic Alzheimer’s disease (AD). In furthering the understanding of mechanisms by which... 
BACE1 | TRPML1 | LDL | cholesterol | ML-SA1 | neurons | amyloid beta | endolysosome pH
Journal Article
Developmental Cell, ISSN 1534-5807, 05/2017, Volume 41, Issue 3, pp. 262 - 273.e6
Gastric acid secretion by parietal cells requires trafficking and exocytosis of H/K-ATPase-rich tubulovesicles (TVs) toward apical membranes in response to... 
TRPML1 | exocytosis | tubulovesicle | cAMP | Ca2+ release | membrane trafficking | LYSOSOMES | STIMULATION | EXOCYTOSIS | MUCOLIPIDOSIS TYPE-IV | ATPASE | MEMBRANES | DEVELOPMENTAL BIOLOGY | RELEASE | IDENTIFICATION | PROTEINS | INTRACELLULAR CA-2 | CELL BIOLOGY | Membrane trafficking | Tubulovesicle | Exocytosis
Journal Article
European Journal of Cell Biology, ISSN 0171-9335, 06/2019, Volume 98, Issue 2-4, pp. 116 - 123
Lysosomal Ca2+ release channel TRPML1 has been suggested to regulate lysosome size by activating calmodulin (CaM). To further understand how TRPML1 and CaM... 
TRPML1 | Lysosome fission | mTORC1 | Lysosomal Ca2 | Lysosomal membrane trafficking | Lysosomal Ca | STORAGE | REFORMATION | COMPLEX | EXOCYTOSIS | AUTOPHAGY | CELL BIOLOGY | MUCOLIPIDOSIS | PATHWAY | CALCIUM | VACUOLE SIZE | ATP RELEASE
Journal Article
Autophagy, ISSN 1554-8627, 10/2016, Volume 12, Issue 10, pp. 1954 - 1955
Lysosomes, the cell's recycling center, undergo nutrient-sensitive adaptive changes in function and biogenesis, i.e., lysosomal adaptation. We recently... 
TRPML1 | 2 | mitophagy | autophagy | ROS | TFEB | lysosomal Ca | lysosome biogenesis | lysosome | lysosomal Ca2 | CELL BIOLOGY | Animals | Lysosomes - metabolism | Reactive Oxygen Species - metabolism | Calcium - metabolism | Models, Biological | Humans | Transient Receptor Potential Channels - metabolism | Autophagy
Journal Article
BBA - Molecular Cell Research, ISSN 0167-4889, 07/2019, Volume 1866, Issue 7, pp. 1111 - 1123
The endolysosomal, non-selective cation channels, two-pore channels (TPCs) and mucolipins (TRPMLs), regulate intracellular membrane dynamics and autophagy.... 
TRPML1 | TRPML3 | TPC2 | TPC1 | TPC | TRPML | MOLECULAR-MECHANISM | CHAPERONE-MEDIATED AUTOPHAGY | BIOCHEMISTRY & MOLECULAR BIOLOGY | KINASE | CYTOSCAPE | GENE ONTOLOGY | MTOR | CELL BIOLOGY | NAADP | CA2 | PATHWAY | ENDOPLASMIC-RETICULUM | Proteins | Magneto-electric machines | Machinery | Analysis | Index Medicus
Journal Article