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Short Communication - In vitro anti trypanosomal activity of some medicinal plants used in the treatment of trypanosomosis in Northern Nigeria, 12/2004
The in vitro trypanocidal activity of 13 medicinal plants used by local herdsmen in Northern Nigeria for the treatment of trypanosomosis was investigated.... 
Medicinal plants, trypanosomosis, Trypanosoma brucei brucei
Journal
05/2013
Acid phosphatase (ACP) activity was demonstrated in blood stream form of Trypanosoma brucei brucei harvested from infected Wister rats by Ion Exchange DEAE... 
enzyme secretion | acid phosphatase | Trypanosoma brucei
Web Resource
01/2013
Eighty healthy adult albino rats of both sexes were used in two experiments to study the effect of Manganese chloride supplementation on the severity of... 
Trypanosoma congolense | manganese chloride supplementation | Trypanosoma brucei
Web Resource
Serum total proteins and creatinine levels in experimental gambian trypanosomosis of vervet monkeys, 12/2005
Although Human African Trypanosomosis presently constitute a major socio-economic problem in several parts of sub-Saharan Africa, conflicting reports on... 
Serum, total proteins, vervet monkeys, creatinine, Trypanosoma brucei gambiense
Journal
Implicating roles of animal reservoir hosts in the resurgence of Gambian trypanosomosis (Sleeping Sickness), 12/2005
Gambian trypanosomosis   (Sleeping Sickness) is a complex and debilitating disease of man. For many years the disease has been ravaging in several parts of... 
Gambian trypanosomosis, Trypanosoma brucei gambiense, animal reservoir hosts, biotechnologies
Journal
Planta Medica, ISSN 0032-0943, 11/2015, Volume 81, Issue 16, p. PM_102
The sesquiterpene lactone 4,15-isoatriplicolide tiglate 1 was recently discovered as an extremely potent trypanocidal agent with an in vitro IC 50 of only 15... 
Trypanosoma brucei | Trypanosoma | Research
Conference Proceeding
Pharmacological Approaches to Antitrypanosomal Chemotherapy, 12/1999
There is an urgent need for new drugs for the chemotherapy of human African trypanosomiasis, Chagas disease and leishmaniasis. Progress has been made in the... 
Trypanosoma brucei - Trypanosoma cruzi - drug delivery systems - liposomes - blood brain barrier
Journal
The Evolution of Trypanosomes Infecting Humans and Primates, 12/1998
Based on phylogenetic analysis of 18S rRNA sequences and clade taxon composition, this paper adopts a biogeographical approach to understanding the... 
Trypanosoma brucei - Trypanosoma cruzi - evolution - phylogenetics - small subunit ribosomal RNA - biogeography
Journal
Full Length Research Paper - Characterization of Trypanosoma brucei gambiense stocks isolated from humans by RAPD fingerprinting in Côte d’Ivoire: another evidence for multiple infections, 01/2004
Trypanosoma brucei gambiense was isolated twice from each of 23 patients in Côte d'Ivoire. Genetic characterization using RAPD (Random Primed Amplified... 
Biotechnology | Human African Trypanosomiasis, Trypanosoma brucei gambiense, RAPD, multiple infections. jb04016
Journal
Mechanisms Mediating Antigenic Variation in Trypanosoma brucei, 12/1999
Antigenic variation in Trypanosoma brucei is a highly sophisticated survival strategy involving switching between the transcription of one of an estimated... 
antigenic variation - Trypanosoma brucei - variant surface glycoprotein (VSG) - VSG expression site
Journal
Programmed cell death in procyclic form Trypanosoma brucei rhodesiense - identification of differentially expressed genes during con a induced death, 12/1999
Trypanosoma brucei rhodesiense can be induced to undergo apoptosis after stimulation with Con A. As cell death in these parasites is associated with de... 
Trypanosoma brucei rhodesiense - programmed cell death - apoptosis - differential gene expression - proto-apoptosis
Journal
Journal of Ethnopharmacology, ISSN 0378-8741, 10/2019, Volume 243, p. 112085
The leaves of are used alone or with other plants by traditional healers in some Southern Nigerian and Ivorian rural villages to treat blood parasitic... 
Pterocarpus santalinoides | Rats | Antitrypanosomal activity | Trypanosoma brucei | Toxicity
Journal Article
05/2011
Organic extracts of the leaves of Azadirachta indica A. Juss. yielded ten antitrypanosomal terpenoids. Three of these (1 - 3), are novel and are derivatives of... 
limonoids | Trypanosoma brucei rhodesiense | antitrypanosomal activity | Meliaceae | Azadirachta indica
Web Resource
2007, ISBN 9781904933274, xi, 423
Book
PLoS Neglected Tropical Diseases, ISSN 1935-2727, 04/2017, Volume 11, Issue 4
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 12/2015, Volume 25, Issue 23, pp. 5504 - 5507
Cynaropicrin is a guaianolide sesquiterpene lactone, which has potent in vitro and in vivo inhibitory activity against , the protozoan parasite that causes... 
Deuterium | Cynaropicrin | Guaianolide | Pharmacokinetic study | Trypanosoma brucei
Journal Article
Planta Medica, ISSN 0032-0943, 11/2015, Volume 81, Issue 16, p. SL5A_03
In continuation of our screening [1] aimed at the identification of natural inhibitors of Glyceraldehyde-3-phosphate-dehydrogenase from Trypanosoma brucei... 
Enzymes | Milk thistle | Research | Trypanosoma brucei
Conference Proceeding
Planta Medica, ISSN 0032-0943, 11/2015, Volume 81, Issue 16, p. PM_99
Trypanosoma brucei is a parasitic flagellate, which currently endangers 70 million people in Africa by causing the deadly sleeping sickness [1]. Only four... 
Alkaloids | Research | Drug discovery | Trypanosoma brucei | Apoptosis
Conference Proceeding
Molecular & Biochemical Parasitology, ISSN 0166-6851, 04/2018, Volume 221, pp. 52 - 55
Aminoacyl-tRNA synthetases are essential for protein synthesis. The single-copy tyrosyl-tRNA synthetase ( TyrRS) of has an unusual structure and forms a... 
Mitochondria | tRNA | Trypanosoma brucei | Aminoacyl-tRNA synthetase | Index Medicus
Journal Article
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