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Angewandte Chemie (International ed.), ISSN 1433-7851, 2018, Volume 57, Issue 45, pp. 14764 - 14768
... them. Herein we report a stereoselective biocatalytic synthesis of β‐branched tryptophan analogues using an engineered variant of Pyrococcus furiosus tryptophan synthase (PfTrpB), PfTrpB7E6... 
tryptophan analogues | biocatalysis | amino acids | directed evolution | lyases | SYNTHASE | METHYLTRYPTOPHAN | ESCHERICHIA-COLI | TRPB | ALPHA-AMINO-ACIDS | CHEMISTRY, MULTIDISCIPLINARY | Stereoselectivity | Spectroscopy | Natural products | Tryptophan synthase | Tryptophan | Amino acids | Biosynthesis | Catalysis | X ray spectra | Mutation | Crystallography | Substrates
Journal Article
PloS one, ISSN 1932-6203, 2010, Volume 5, Issue 9, pp. e12684 - 8
Journal Article
Angewandte Chemie, ISSN 0044-8249, 2018, Volume 130, Issue 45, pp. 14980 - 14984
... them. Herein we report a stereoselective biocatalytic synthesis of β‐branched tryptophan analogues using an engineered variant of Pyrococcus furiosus tryptophan synthase (PfTrpB), PfTrpB7E6... 
Gerichtete Weiterentwicklung | Aminosäuren | Biokatalyse | Tryptophan-Analoga | Lyasen | Stereoselectivity | Spectroscopy | Natural products | Tryptophan synthase | Tryptophan | Amino acids | Biosynthesis | Catalysis | X ray spectra | Mutation | Crystallography | Substrates
Journal Article
Amino acids, ISSN 0939-4451, 05/2016, Volume 48, Issue 5, pp. 1309 - 1318
Journal Article
Angewandte Chemie (International ed.), ISSN 1433-7851, 2016, Volume 55, Issue 39, pp. 11845 - 11848
.... This change was achieved by using a substrate analogue containing an olefin moiety. We also showed that two SAM analogues containing different nucleoside functionalities initiate the radical... 
radical addition | thiopeptides | SAM analogues | S-adenosylmethionine | biosynthesis | TRYPTOPHAN | CATALYSIS | METHIONINE ENZYME NOSL | MECHANISTIC INSIGHTS | CHEMISTRY, MULTIDISCIPLINARY | LYASE | Sulfur compounds | Enzymes | Hydrogen | Olefins | Physiological aspects | Nucleosides | Free radicals (Chemistry)
Journal Article