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Experimental Neurology, ISSN 0014-4886, 06/2012, Volume 235, Issue 2, pp. 484 - 490
Micro RNAs (miRNAs), small and labile ~. 22 nucleotide-sized fragments of single stranded RNA, are important regulators of messenger (mRNA) complexity and in... 
Amyloidogenesis | Complement factor H (CFH) | Synapsin-2 (SYN-2) | Alzheimer's disease (AD) | Evolution | MiRNA-146a | Tetraspanin-12 (TSPAN12) | Micro RNA 125b (miRNA-125b) | 15-lipoxygenase (15-LOX)
Journal Article
by Ji, GH and Liang, HB and Wang, FL and Wang, N and Fu, SB and Cui, XB
MOLECULES AND CELLS, ISSN 1016-8478, 07/2019, Volume 42, Issue 7, pp. 557 - 567
TSPAN12, a member of the tetraspanin family, has been highly connected with the pathogenesis of cancer. Its biological function, however, especially in ovarian... 
proliferation | cell cycle | ovarian cancer | BIOCHEMISTRY & MOLECULAR BIOLOGY | GROWTH | TSPAN12 | CELL BIOLOGY
Journal Article
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, ISSN 0146-0404, 06/2019, Volume 60, Issue 7, pp. 2659 - 2666
PURPOSE. The purpose of this study was to investigate the genetic mutation spectrum in Chinese patients with familial exudative vitreoretinopathy-associated... 
next-generation sequencing | FZD4 | genetic mutation spectrum | SURGICAL OUTCOMES | CLINICAL-FEATURES | IDENTIFICATION | TSPAN12 | genotype-phenotype association | rhegmatogenous retinal detachment | ZNF408 | GENES | OPHTHALMOLOGY | LRP5 MUTATIONS | familial exudative vitreoretinopathy | NDP | CHINESE PATIENTS
Journal Article
OPHTHALMIC SURGERY LASERS & IMAGING RETINA, ISSN 2325-8160, 02/2019, Volume 50, Issue 2, pp. 120 - 124
Familial exudative vitreoretinopathy (FEVR) is a rare hereditary ocular disorder characterized by incomplete or abnormal development of peripheral retinal... 
SURGERY | NORRIE-DISEASE | ZNF408 | FZD4 | LRP5 | OPHTHALMOLOGY | RETINOPATHY | RETINA | MUTATIONS | TSPAN12 | IDENTIFICATION
Journal Article
Journal Article
Neuroscience Letters, ISSN 0304-3940, 07/2011, Volume 499, Issue 2, pp. 109 - 113
► miRNA-146a is a brain-enriched miRNA involved in inflammation in multiple human brain cell types. ► miRNA-146a is up-regulated in human brain cells stressed... 
Complement factor H (CFH) | Brain gene expression | microRNA (miRNA) | Neurodegeneration | Small RNA | Post-transcriptional control | Microglial cells | Human astroglial cells | Neuroinflammation | Tetraspanin 12 (TSPAN12) | Interleukin-1 receptor associated kinase 1 (IRAK-1) | MicroRNA (miRNA) | MOUSE TRIGEMINAL GANGLION | ALZHEIMERS-DISEASE | TRANSCRIPTION | DOWN-REGULATION | INDUCTION | NANOMOLAR ALUMINUM | NEUROSCIENCES | HIPPOCAMPUS | NF-KAPPA-B | UP-REGULATION | HUMAN BRAIN-CELLS | Complement Factor H - antagonists & inhibitors | Amyloid beta-Peptides - physiology | Neurons - pathology | Coculture Techniques | Humans | Astrocytes - pathology | Cells, Cultured | Gene Expression Regulation | MicroRNAs - biosynthesis | Peptide Fragments - physiology | Astrocytes - physiology | Microglia - physiology | Neurons - physiology | Tumor Necrosis Factor-alpha - physiology | Microglia - pathology | MicroRNAs - genetics | MicroRNAs - physiology | Complement Factor H - genetics | Inflammation Mediators - physiology | Peptides | RNA | Gene expression | Index Medicus | IRAK protein | Brain | Neurodegenerative diseases | Nervous system | beta -Amyloid | Inflammation | mRNA | Nucleotides | Macrophages | Stress | Interleukin 1 | Alzheimer's disease | Tumor necrosis factor- alpha | Interleukin-1 receptor associated kinase 1 | IRAK-1
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2018, Volume 115, Issue 50, pp. E11827 - E11836
beta-Catenin signaling controls the development and maintenance of the blood-brain barrier (BBB) and the blood-retina barrier (BRB), but the division of labor... 
Vascular endothelial cells | β-catenin signaling | Central nervous system | Mouse genetics | VASCULAR DEVELOPMENT | FZD4 | MULTIDISCIPLINARY SCIENCES | mouse genetics | TSPAN12 | beta-catenin signaling | central nervous system | PROTEIN-COUPLED RECEPTOR | vascular endothelial cells | MUTATIONS | LIGAND | FAMILIAL EXUDATIVE VITREORETINOPATHY | CNS ANGIOGENESIS | RECK | GPR124 | Blood-Brain Barrier - cytology | Blood-Retinal Barrier - cytology | Nerve Tissue Proteins - deficiency | Tetraspanins - physiology | Wnt Proteins - deficiency | Blood-Retinal Barrier - growth & development | Wnt Proteins - genetics | Tetraspanins - deficiency | Blood-Brain Barrier - physiology | Blood-Brain Barrier - growth & development | beta Catenin - physiology | Cell Culture Techniques | Eye Proteins - genetics | Tetraspanins - genetics | Frizzled Receptors - deficiency | Nerve Tissue Proteins - physiology | Blood-Retinal Barrier - physiology | Signal Transduction | Proto-Oncogene Proteins - genetics | Frizzled Receptors - physiology | Proto-Oncogene Proteins - deficiency | Nerve Tissue Proteins - genetics | Mice, Knockout | Animals | Frizzled Receptors - genetics | Models, Biological | Proto-Oncogene Proteins - physiology | Eye Proteins - physiology | Mice | Wnt Proteins - physiology | Models, Neurological | Physiological aspects | Retina | Blood-brain barrier | Wnt proteins | Cerebellum | Brain | Phenotypes | Redundancy | Nervous system | Maintenance | Signalling systems | Blood | Endothelial cells | β-catenin | Heterogeneity | Receptors | Rodents | Barriers | Genetic analysis | Ligands | Vascular endothelial growth factor | Division of labor | Index Medicus | Biological Sciences | PNAS Plus
Journal Article
American Journal of Translational Research, ISSN 1943-8141, 2017, Volume 9, Issue 2, pp. 812 - 822
Tetraspanin 12 (TSPAN12), as an earliest member of tetraspanin family, has been recently shown to be highly expressed in several malignant tumors, such as lung... 
Cell proliferation | ShRNA | TSPAN12 | Invasion | Colorectal cancer | MEDICINE, RESEARCH & EXPERIMENTAL | CELLS | cell proliferation | TUMOR-SUPPRESSOR GENE | CATENIN | E-CADHERIN | BREAST-CANCER | TETRASPANINS | MICRODOMAINS | EVOLUTION | invasion | ONCOLOGY | shRNA | WEB | REVEALS
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 04/2017, Volume 486, Issue 2, pp. 349 - 356
Journal Article