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Journal of Nuclear Medicine, ISSN 0161-5505, 01/2019, Volume 60, Issue 1, pp. 122 - 128
Neuroinflammation plays a key role in neuronal injury after ischemic stroke. PET imaging of translocator protein 18 kDa (TSPO) permits longitudinal,... 
Neuroinflammation | TSPO | Ischemic stroke | PET
Journal Article
Journal Article
International Journal of Molecular Sciences, ISSN 1661-6596, 07/2016, Volume 17, Issue 7, p. 1085
  The 18-kDa translocator protein (TSPO) levels are associated with brain, breast, and prostate cancer progression and have emerged as viable targets for... 
Tc(CO) | TSPO | Tricarbonyltechnetium-99m | Translocator protein | SPECT | TSPO-rich tumors | Proteins | Chloroplasts | Chemical synthesis | Cancer | translocator protein | 99mTc(CO)3
Journal Article
JOURNAL OF NUCLEAR MEDICINE, ISSN 0161-5505, 06/2017, Volume 58, Issue 6, pp. 989 - 995
I-123-CLINDE is a radiotracer developed for SPECT and targets the 18-kDa translocator protein (TSPO). TSPO is upregulated in glial cells and used as a measure... 
CELLS | RADIOLIGAND | PET IMAGES | QUANTIFICATION | polymorphism | TSPO imaging | variability | second-generation TSPO tracer | STANDARDIZED UPTAKE | MULTIPLE-SCLEROSIS | 18 KDA TSPO | NEUROINFLAMMATION | BINDING | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Journal Article
Journal of Nuclear Medicine, ISSN 0161-5505, 08/2018, Volume 59, Issue 8, pp. 1260 - 1266
Journal Article
Journal of Neural Transmission, ISSN 0300-9564, 05/2018, Volume 125, Issue 5, pp. 847 - 867
Journal Article
Journal of Nuclear Medicine, ISSN 0161-5505, 01/2019, Volume 60, Issue 1, pp. 122 - 128
Neuroinflammation plays a key role in neuronal injury after ischemic stroke. PET imaging of translocator protein 18 kDa (TSPO) permits longitudinal,... 
Neurology | TSPO | neuroinflammation | ischemic stroke | PET
Journal Article
Experimental Eye Research, ISSN 0014-4835, 11/2019, Volume 188, p. 107816
Translocator protein (18 kDa) (TSPO) is a mitochondrial protein expressed by reactive microglia and astrocytes at the site of neuronal injury. Although TSPO... 
Retinal degeneration | Retina | TSPO | RPE | Microglia
Journal Article
Journal of Cerebral Blood Flow and Metabolism, ISSN 0271-678X, 09/2010, Volume 30, Issue 9, pp. 1608 - 1618
Journal Article
International Journal of Molecular Sciences, ISSN 1661-6596, 04/2017, Volume 18, Issue 4, pp. 786 - 786
It is known that knockdown of the mitochondrial 18 kDa translocator protein (TSPO) as well as TSPO ligands modulate various functions, including functions... 
Mitochondria | Modulation of nuclear gene expression | Microscopy | Cell nucleus | Retrograde mitochondrial-nuclear signaling pathway | TSPO ligand | Mitochondrial 18 kDa translocator protein (TSPO) | PK 11195 | 2-Cl-MGV-1 | TRANSLOCATOR-PROTEIN TSPO | APOPTOSIS | modulation of nuclear gene expression | mitochondria | BIOCHEMISTRY & MOLECULAR BIOLOGY | RAT-BRAIN MITOCHONDRIA | CA2+-INDUCED PERMEABILITY TRANSITION | OSTEOBLAST-LIKE CELLS | CHEMISTRY, MULTIDISCIPLINARY | NEURODEGENERATIVE DISEASES | retrograde mitochondrial-nuclear signaling pathway | cell nucleus | 18 KDA TSPO | mitochondrial 18 kDa translocator protein (TSPO) | HUMAN GLIOBLASTOMA CELLS | PERIPHERAL BENZODIAZEPINE-RECEPTOR | DRUG DEVELOPMENT | microscopy | Cell Survival - drug effects | Receptors, GABA - genetics | Oligonucleotide Array Sequence Analysis - methods | Humans | Gene Expression Profiling - methods | Cell Adhesion - drug effects | Cell Movement - drug effects | Isoquinolines - pharmacology | Cell Nucleus - genetics | Glioblastoma - genetics | Mitochondria - genetics | Signal Transduction - drug effects | Cell Differentiation - drug effects | Cell Line, Tumor | Ligands | Cell Proliferation - drug effects | Gene Expression Regulation, Neoplastic - drug effects | Cell proliferation | Transcription factors | RNA-directed DNA polymerase | Leukocyte migration | Glioblastoma | Gene expression | Retrograde transport | Polymerase chain reaction | Immediate-early proteins | Angiogenesis | Signal transduction | DNA microarrays | Cell death | Tumorigenesis | Glioblastoma cells | Cell migration | Cancer | Apoptosis
Journal Article
JOURNAL OF NUCLEAR MEDICINE, ISSN 0161-5505, 02/2017, Volume 58, Issue 2, pp. 320 - 325
For PET imaging of 18-kDa translocator protein (TSPO), a biomarker of neuroinflammation, most second-generation radioligands are sensitive to the single... 
GENETIC-POLYMORPHISM | BIOMARKER | C-11-ER176 | 18-kDa translocator protein (TSPO) | BENZODIAZEPINE-RECEPTOR | 18 KDA | NOMENCLATURE | rs6971 polymorphism | NEUROINFLAMMATION | INFLAMMATION | IN-VIVO | TSPO | positron emission tomography | BINDING | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | XBD173
Journal Article
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