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Molecules (Basel, Switzerland), ISSN 1420-3049, 2017, Volume 22, Issue 9, p. 1470
Journal Article
Cancer Research, ISSN 0008-5472, 03/1998, Volume 58, Issue 6, pp. 1111 - 1115
Eleutherobin is a novel natural product isolated from a marine soft coral that is extremely potent for inducing tubulin polymerization in vitro and is cytotoxic for cancer cells with an IC50 similar... 
DRUG | STABILIZES MICROTUBULES | ONCOLOGY | CELL-LINES | INVITRO | Binding, Competitive | Alkaloids - pharmacology | Paclitaxel - pharmacology | Humans | Ovarian Neoplasms - pathology | Tubulin - metabolism | Animals | Cattle | Microtubules - drug effects | Colonic Neoplasms - pathology | Diterpenes | Female | Antineoplastic Agents - pharmacology | Tumor Cells, Cultured | Polymers | Binding Sites | Growth Inhibitors - pharmacology
Journal Article
International Journal of Molecular Sciences, ISSN 1661-6596, 09/2018, Volume 19, Issue 9, p. 2552
...) cell line and for its potential to induce apoptosis and also to inhibit tubulin polymerization and/or epidermal growth factor receptor-tyrosine kinase (EGFR-TK) phosphorylation... 
Benzofuran-chalcones | Cytotoxicity | Tubulin | EGFR | Molecular docking | Apoptosis | DOMAIN | ANALOGS | BENZOFURAN DERIVATIVES | BIOCHEMISTRY & MOLECULAR BIOLOGY | tubulin | apoptosis | benzofuran-chalcones | ANTITUMOR | CHEMISTRY, MULTIDISCIPLINARY | BREAST-CANCER | molecular docking | GROWTH | CHALCONE | ACTINOMYCIN-D | cytotoxicity | Chalcones - chemistry | Tubulin Modulators - chemistry | ErbB Receptors - metabolism | Cell Survival | Tubulin Modulators - pharmacology | Humans | Structure-Activity Relationship | Drug Discovery | Molecular Dynamics Simulation | Tubulin Modulators - chemical synthesis | Tubulin - metabolism | Chalcones - chemical synthesis | MCF-7 Cells | Furans - chemistry | Chalcones - pharmacology | Cell Proliferation - drug effects | Molecular Docking Simulation | Molecular Structure | Phosphorylation - drug effects | Tubulin - chemistry | Protein Multimerization - drug effects | Drug Screening Assays, Antitumor | Actinomycin | Phosphorylation | Hybrids | Toxicity | Hydrophobicity | Kinases | Caspase-3 | Proteins | Receptors | Epidermal growth factor | Protein-tyrosine kinase receptors | Chemical synthesis | Growth factors | Protein-tyrosine kinase | Tyrosine | Epidermal growth factor receptors | Polymerization | Caspase | Breast cancer | Benzofuran | Annexin V | Nuclear magnetic resonance--NMR | Binding sites
Journal Article
Arabian Journal of Chemistry, ISSN 1878-5352, 12/2019, Volume 12, Issue 8, pp. 4740 - 4755
.... Cytotoxicity effect of promising conjugates (6d and 6g) was confirmed by tubulin polymerization assay, cell cycle arrest... 
Cytotoxicity | Cinnamides | Tubulin polymerization inhibitors | Apoptosis | MICROTUBULE | AGENTS | CHEMISTRY, MULTIDISCIPLINARY
Journal Article
ACS Medicinal Chemistry Letters, ISSN 1948-5875, 10/2018, Volume 9, Issue 10, pp. 974 - 979
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 11/2014, Volume 87, pp. 89 - 124
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 2009, Volume 240, Issue 2, pp. 143 - 148
.... The goal of the present work was to measure the effect of the organophosphorus agent chlorpyrifos oxon on tubulin polymerization... 
Nanoimages | Chlorpyrifos oxon | Mass spectrometry | Tubulin polymerization | AGRICULTURAL HEALTH | MECHANISM | MICROTUBULE | LICENSED PESTICIDE APPLICATORS | COLCHICINE | FORCE MICROSCOPY | DISEASE | PHARMACOLOGY & PHARMACY | TOXICOLOGY | BINDING | EXPOSURE | Tyrosine | Cholinesterase Inhibitors - toxicity | Chlorpyrifos - analogs & derivatives | Protein Multimerization | Guanosine Triphosphate - metabolism | Tubulin - ultrastructure | Nanostructures | Tubulin - drug effects | Chlorpyrifos - metabolism | Dose-Response Relationship, Drug | Neurotoxicity Syndromes - etiology | Tandem Mass Spectrometry | Tubulin - metabolism | Animals | Spectrometry, Mass, Electrospray Ionization | Cholinesterase Inhibitors - metabolism | Neurotoxicity Syndromes - pathology | Cattle | Chlorpyrifos - toxicity | Microscopy, Atomic Force | Neurotoxicity Syndromes - metabolism | Tubulin Modulators - metabolism | Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | Tubulin Modulators - toxicity | Atomic force microscopy | Enzyme inhibitors | Ionization | Polymerization | Tubulins | Magnesium compounds | Index Medicus | NERVOUS SYSTEM DISEASES | MICROTUBULES | TYROSINE | MASS SPECTROSCOPY | POLYMERIZATION | TOXICITY | PROTEINS | 60 APPLIED LIFE SCIENCES | INSECTICIDES | NERVE CELLS | nanoimages | mass spectrometry | tubulin polymerization | chlorpyrifos oxon
Journal Article